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Advances and Challenges in Pharmaceutical Technology. Materials, Process Development and Drug Delivery Strategies

  • Book

  • February 2021
  • Elsevier Science and Technology
  • ID: 4991140

Advances and Challenges in Pharmaceutical Technology: Materials, Process Development and Drug Delivery Strategies examines recent advancements in pharmaceutical technology. The book discusses common formulation strategies, including the use of tools for statistical formulation optimization, Quality by design (QbD), process analytical technology, and the uses of various pharmaceutical biomaterials, including natural polymers, synthetic polymers, modified natural polymers, bioceramics, and other bioinorganics. In addition, the book covers rapid advancements in the field by providing a thorough understanding of pharmaceutical processes, formulation developments, explorations, and exploitation of various pharmaceutical biomaterials to formulate pharmaceutical dosage forms.

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Table of Contents

1. Natural polymers as useful pharmaceutical excipients2. Synthetic and semi-synthetic polymers for pharmaceutical applications 3. Engineered plant gums as improved pharmaceutical applications 4. Grafted polysaccharides as advanced pharmaceutical excipients5. Smart polymers in advanced drug delivery 6. Design and development of dosage forms: Influences of anatomy and administration routes 7. Effective formulation development strategies for poorly soluble drugs8. Formulation strategies to improve the bioavailability of poorly absorbed drugs9. Drug transport across the biological barriers present in human body10. Pharmaceutical coating processes11. Process analytical technology (PAT) tools: Uses in pharmaceutical manufacturing12. Pharmaceutical product development: A quality by design (QbD) approach13. Polymeric gels as drug delivery vehicles 14. Nanoparticles as effective drug delivery carriers 15. Iontophoretic drug permeation enhancement techniques 16. MEMS based drug delivery systems17. Ultrasonic drug delivery devices 18. Recent developments in siRNA delivery strategies

Authors

Amit Kumar Nayak Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.

Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.

Kunal Pal Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, Odisha, India.. Dr. Kunal Pal is a Professor in the Department of Biotechnology and Medical Engineering, National Institute of Technology Rourkela, India. His major research interests revolve around biomedical signal processing, biomedical equipment design, soft materials, and controlled drug delivery. He has published more than 100 publications in SCI-cited journals of high repute. Indranil Banerjee Assistant Professor, Department of Bioscience and Bioengineering, Indian Institute of Technology Jodhpur, Rajasthan, India. Prof. Indranil Banerjee did his Ph. D. in Biotechnology (Tissue Engineering) from Indian Institute of Technology Kharagpur, India in the year 2011. Presently, is holding the position of an Assistant Professor in the Department of Biotechnology and Medical Engineering at National Institute of Technology- Rourkela. He is the Professor-in-Charge of the Bioprocess Laboratory and Biomicrofludics Laboratory. His group is actively involved in understanding the cell physiology in response to biomaterials developed on a length scale (nano to macro). He was a visiting scientist in Maxplanck Institute of Intelligent System, Germany. Dr. Banerjee has authored 35 SCI cited publications in various journals of repute with a total citation of more than 450. He is also serving as industrial consultant. Samarendra Maji Assistant Professor, Department of Chemistry, Faculty of Engineering and Technology, SRM Institute of Science and Technology, SRM Nagar, Kattankulathur, Tamilnadu, India. Dr. Maji obtained his Ph. D. in Materials Science from Indian Institute of Technology Kharagpur, India in 2010. After 1.5 years of postdoctoral research with Professor Dr. Seema Agarwal and Professor Dr. Andreas Greiner at Philipps University Marburg (Germany), he moved to Ghent University (Belgium) for his second postdoctoral training with Professor Richard Hoogenboom. From July 2017, he was appointed as Assistant Professor at the Department of Chemistry, SRM Institute of Science and Technology (SRMIST), Chennai, India. He has authored more than 40 SCI cited publications in various journals of repute and book chapters. He is recipient of prestigious Alexander von Humboldt fellowship of Germany (2010) and FWO Pegasus Marie Curie Fellowship of Belgium (2012). Upendranath Nanda Department of Pharmaceutics, Seemanta Institute of Pharmaceutical Sciences, Mayurbhanj, Odisha, India. Dr. Nanda (M. Pharm, Ph.D) has over 30 years of teaching and research experience in the field of Pharmaceutics, especially in the development and characterization of novel drug delivery systems. He has earned his Ph. D. in Pharmacy from Utkal University, India in 2009. Currently, Dr. Nanda is working as Professor-cum-Principal of Seemanta Institute of Pharmaceutical Sciences, Odisha, India. Till date, he has authored over 21 publications in various journals of International repute. He has been a reviewer of several journals of high repute.