Covering all aspects of neuropathology, this updated volume in the Diagnostic Pathology series is an excellent point-of-care resource for pathologists at all levels of experience and training-both as a quick reference and as an efficient review to improve knowledge and skills. The third edition is an easy-to-use, one-stop reference for the most recent clinical, pathological, histological, and molecular knowledge in the field. It offers complete information on lesions of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, vascular, and cortical dysplastic lesions, enabling you to arrive at the correct diagnosis and prepare actionable, useful reports.
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Incorporates new WHO Classification of Tumors of the Central Nervous System, 5th Edition
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Offers information on neoplasms of the brain, sellar region, and peripheral nerves, as well as benign cysts and selected infectious, inflammatory, reactive, and vascular lesions, aiding you in arriving at the correct diagnosis
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Emphasizes surgical pathology but also provides significant content on nonneoplastic diseases that present with focal lesions, especially those that are potentially misinterpreted as neoplasms
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Features new and updated chapters detailing several types of tumors that have been reclassified due to recent molecular driver information, cIMPACT-NOW recommendations, and the WHO Classification, 5th Edition
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Features nearly 1,700 annotated images throughout, including neuroimaging studies, histology and immunohistochemical stains, and high-quality medical illustrations
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Incorporates time-saving features such as a templated, highly formatted design; concise, bulleted text; a variety of test data tables; key facts in each chapter; and an extensive index
- Includes the enhanced eBook version, which allows you to access all text, figures, and references on a variety of devices
Table of Contents
NeoplasticBrain and Spinal Cord
Diffuse Astrocytic and Oligodendroglial Tumors
Diffuse Astrocytoma, IDH-Mutant, WHO Grade II
Diffuse Astrocytoma, IDH-Wildtype, WHO Grade II (Provisional Entity)
Anaplastic Astrocytoma, IDH-Mutant, WHO Grade III
Anaplastic Astrocytoma, IDH-Wildtype, WHO Grade III
Glioblastoma, IDH-Wildtype
Granular Cell Astrocytoma of the Cerebrum
Gliosarcoma
Glioblastoma, IDH Mutant
Diffuse Midline Glioma, H3 K27M Mutant
H3 G34-Mutant Gliomas, IDH-Wildtype (Provisional Entity)
Oligodendroglioma
Anaplastic Oligodendroglioma
Mixed Oligoastrocytoma
Other Astrocytic Tumors
Pilocytic Astrocytoma
Pilomyxoid Astrocytoma
Subependymal Giant Cell Astrocytoma
Pleomorphic Xanthoastrocytoma
Anaplastic Pleomorphic Xanthoastrocytoma
Pediatric Low-Grade Glioma/Glioneuronal Tumors (Provisional Entities)
Ependymal Tumors
Subependymoma
Myxopapillary Ependymoma
Ependymoma
Ependymoma, *RELA* Fusion-Positive
Anaplastic Ependymoma
Other Gliomas
Chordoid Glioma of 3rd Ventricle
Angiocentric Glioma
Astroblastoma
Choroid Plexus Tumors
Choroid Plexus Papilloma and Atypical Papilloma
Choroid Plexus Carcinoma
Neuronal and Mixed Neuronal-Glial Tumors
Dysembryoplastic Neuroepithelial Tumor
Gangliocytoma and Ganglioglioma
Dysplastic Cerebellar Gangliocytoma (Lhermitte-Duclos Disease)
Desmoplastic Infantile Ganglioglioma
Papillary Glioneuronal Tumor
Rosette-Forming Glioneuronal Tumor of 4th Ventricle
Diffuse Leptomeningeal Glioneuronal Tumor
Malignant Glioneuronal Tumors
Central Neurocytoma
Extraventricular Neurocytoma
Cerebellar Liponeurocytoma
Paraganglioma of Filum Terminale
Tumors of the Pineal Region
Pineal Parenchymal Neoplasms
Papillary Tumor of the Pineal Region
Pineal Anlage Tumor
Embryonal Tumors
Medulloblastoma
CNS Embryonal Neoplasms
Embryonal Tumor With Multilayered Rosettes, C19MC Altered
Ewing Sarcoma
Atypical Teratoid/Rhabdoid Tumor
Germ Cell Tumors
Germinoma
Teratomas
Other Germ Cell Tumors
Lymphomas and Histiocytic Tumors
Primary Central Nervous System Lymphoma
Lymphomatosis Cerebri
Lymphomatoid Granulomatosis
Intravascular Lymphomatosis
Primary Amyloidoma
Langerhans Cell Histiocytosis
Erdheim-Chester Disease
Rosai-Dorfman Disease
Metastatic Tumors
Metastatic Neoplasms, Intraparenchymal, Brain and Spinal Cord
Sellar Region
Adenohypophyseal Neoplasia and Hyperplasia
Pituitary Adenoma
Prolactinoma
Somatotroph Adenoma
Corticotroph Adenoma
Gonadotroph Adenoma
Thyrotroph Adenoma
Plurihormonal Adenoma
Null Cell Adenoma
Pituitary Hyperplasia
Pituitary Carcinoma
TTF-Mediated Neurohypophyseal Neoplasms
Granular Cell Tumor of the Sellar Region
Pituicytoma
Spindle Cell Oncocytoma
Craniopharyngiomas
Adamantinomatous Craniopharyngioma
Papillary Craniopharyngioma
Miscellaneous Neoplasms
Pituitary Blastoma
Secondary Neoplasms of the Pituitary and Sellar Region
Hypothalamic Hamartoma
Meningiomas and Mesenchymal Nonmeningothelial Tumors
Meningioma
Solitary Fibrous Tumor/Hemangiopericytoma
Hemangioblastoma
Primary Melanocytic Neoplasms
Osteocartilaginous Neoplasms
Notochordal Tumors
Fibrosarcoma
Smooth Muscle Neoplasms
Adipocytic Neoplasms
Meningeal Glioma and Gliomatosis
Metastatic Neoplasms, Intracranial and Intraspinal Meninges
Tumors of Cranial and Paraspinal Nerves
Schwannoma Variants
Conventional Schwannoma
Cellular Schwannoma
Plexiform Schwannoma
Melanotic Schwannoma
Neurofibroma
Plexiform Neurofibroma
Localized Intraneural Neurofibroma
Extraneural Neurofibroma Variants
Perineurioma
Intraneural Perineurioma
Soft Tissue Perineurioma
Primary Malignant Neoplasms of Nerve
Malignant Peripheral Nerve Sheath Tumor
Lipoma of 8th Cranial Nerve
Lipoma of 8th Cranial Nerve
Familial Tumor Syndromes
Neurofibromatosis
Neurofibromatosis 1
Neurofibromatosis 2
Schwannomatosis
Other
von Hippel-Lindau Syndrome
Tuberous Sclerosis Complex
Turcot Syndrome
Nonneoplastic
Benign Cysts
Arachnoid Cyst
Epidermoid and Dermoid Cysts
Colloid Cyst
Rathke Cleft Cyst
Endodermal Cyst
Ependymal Cyst
Pineal Cyst
Facet Joint Synovial Cyst
Infectious, Inflammatory, and Reactive Lesions
Demyelinating Diseases
Demyelinating Disease (Multiple Sclerosis-Tumefactive Demyelination)
Bacterial Infections
Abscess and Cerebritis
Whipple Disease
Tuberculosis
Viral Infections
Herpes Simplex Encephalitis
Progressive Multifocal Leukoencephalopathy
HIV Encephalitis
Other Viral Infections
Fungal Infections
Fungal Infections
Protozoal and Parasitic Infections
Toxoplasmosis
Amebiasis
Cysticercosis
Miscellaneous Parasitic Infections
Other Inflammatory Diseases
Sarcoidosis
Rasmussen Encephalitis
Paraneoplastic Disease
Textiloma (Muslinoma, Gauzoma, Gossypiboma)
Inflammatory Pseudotumors
Lymphocytic Hypophysitis
Reactive Conditions and Noninflammatory Pseudoneoplasms
Meningioangiomatosis
Meningeal Response to Intracranial Hypotension
Radiation Necrosis
Calcifying Pseudoneoplasm of the Neuraxis
Vascular Diseases
Vascular Malformations and Neoplasms
Telangiectasis
Cavernous Angioma
Arteriovenous Malformation
Capillary Hemangioma
Vascular Lesions
Subdural Hematoma
Infarct
Vasculitis and Vasculopathy
Primary Angiitis of Central Nervous System
Amyloid (Congophilic) Angiopathy
Cortical Dysplasia
Cortical Dysplasia
