Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions.
This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry.
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Table of Contents
1. Green synthetic approaches for biologically relevant heterocycles: Advanced synthetic techniques an overview 2. Use of Ball Milling for the Synthesis of Biologically Active Heterocycles 3. High pressure cycloaddition reactions in the synthesis of biologically relevant heterocycles 4. Microwave-induced synthesis of heterocycles of medicinal interests 5. Multicomponent reactions under microwave irradiation: a green path to biologically important heterocycles 6. Application of microwave irradiation in the synthesis of P-heterocycles 7. Green approaches for synthesis and functionalization of indole-based heterocycles of biological relevance 8. Sustainable one-pot domino reactions to access significant heterocycles employing dithioesters and their derivatives 9. Solvent-free synthesis of biologically relevant heterocyclic skeletons 10. Photocatalytic Minisci reaction: A promising and eco-friendly route to functionalize heteroaromatics of biological interest 11. Porous catalytic systems in the synthesis of bioactive heterocycles and related compounds 12. Advances on greener processes for triazole synthesis via azide-alkyne cycloaddition reactions 13. Green Chemistry of Imines in Heterocyclic Synthesis 14. Transition-metal-free synthesis of benzo-fused five- and six-membered heterocycles employing arynes 15. Multicomponent approach for the sustainable synthesis of lawsone based heterocycles 16. Sustainable synthesis of Meldrum's acid derived heterocycles via multicomponent reactions
Authors
Goutam Brahmachari Goutam Brahmachari, PhDFull Professor, Organic Chemistry, Department of Chemistry, Visva-Bharati (a Central University), Santiniketan, West Bengal, India.Born on April 14, 1969 in Barala, a village in the district of Murshidabad (West Bengal, India), Goutam Brahmachari had his early education in his native place. He received his high school degree in scientific studies in 1986 at Barala R. D. Sen High School under the West Bengal Council of Higher Secondary Education (WBCHSE). Then, he moved to Visva-Bharati (a Central University founded by Rabindranath Tagore at Santiniketan, West Bengal, India) to study chemistry at the undergraduate level. After graduating from this university in 1990, he completed his master's in 1992, specializing in organic chemistry. After receiving his Ph.D. 1997 in chemistry from the same university, he joined his alma mater the next year and has been a full professor of chemistry since 2011. The research interests of Prof. Brahmachari's group include synthetic organic chemistry, green chemistry, natural products chemistry, and the medicinal chemistry of natural and natural product-inspired synthetic molecules. With more than 25 years of experience in teaching and research, he has produced over 260 scientific publications, including original research papers, review articles, books, and invited book chapters in the field of natural products and green chemistry. He has already authored/edited 27 books published by internationally reputed major publishing houses, namely, Elsevier Science (The Netherlands), Academic Press (Oxford), Wiley-VCH (Germany), Alpha Science International (Oxford), De Gruyter (Germany), World Scientific (Singapore), CRC Press (Taylor & Francis Group, USA), Royal Society of Chemistry (Cambridge), etc. Prof. Brahmachari serves several scientific bodies in India and abroad, and also many international journals as an editorial member. He has also been serving as co-editor-in-chief for Current Green Chemistry. Prof. Brahmachari is the founder series editor of the Elsevier Book Series 'Natural Product Drug Discovery'. Prof. Brahmachari is an elected fellow of the Royal Society of Chemistry and a recipient of the CRSI (Chemical Research Society of India) Bronze Medal-2021 (for his contribution to research in chemistry), Dr Basudev Banerjee Memorial Award-2021 (for his contribution to the field of chemical sciences) from the Indian Chemical Society, INSA (Indian National Science Academy) Teachers Award-2019, Dr Kalam Best Teaching Faculty Award-2017, and Academic Brilliance Award, 2015 (Excellence in Research). Prof. Brahmachari was featured in the World Ranking of the Top 2% Scientists (Organic Chemistry Category) in 2020-23, the AD Scientific World Ranking of Scientists in 2022-2024, and as the Scholar GPS Highly Ranked Scholar-2024 (Lifetime, securing a position in the top 0.05% of all scholars worldwide).
