Frontiers in Clinical Drug Research - Anti-Allergy Agents is a book series comprising of a selection of updated review articles relevant to the recent development of pharmacological agents used for the treatment of allergies. The scope of the reviews includes clinical trials of anti-inflammatory and anti-allergic drugs, drug delivery strategies used to treat specific allergies (such as inflammation, asthma and dermatological allergies), lifestyle dependent modes of therapies and the immunological or metabolic mechanisms that are of interest to researchers as targets for new drugs.
The fourth volume of this series brings 5 reviews which cover the following topics:
Anti-inflammatory and Immunomodulatory properties of medicinal plant products
Helminth therapy: a new tool for treatment of allergic diseases
An overview of anti-allergic medications in paediatric population
In-silico approaches in drug discovery and design of anti-allergic agents
Microbiota and allergy: possible Interventions
Frontiers in Clinical Drug Research - Anti-Allergy Agents will be of interest to immunologists and drug discovery researchers interested in anti-allergic drug therapy as the series provides relevant cutting edge reviews written by experts in this rapidly expanding field.
The fourth volume of this series brings 5 reviews which cover the following topics:
Anti-inflammatory and Immunomodulatory properties of medicinal plant products
Helminth therapy: a new tool for treatment of allergic diseases
An overview of anti-allergic medications in paediatric population
In-silico approaches in drug discovery and design of anti-allergic agents
Microbiota and allergy: possible Interventions
Frontiers in Clinical Drug Research - Anti-Allergy Agents will be of interest to immunologists and drug discovery researchers interested in anti-allergic drug therapy as the series provides relevant cutting edge reviews written by experts in this rapidly expanding field.
Table of Contents
Chapter 1 Anti-Inflammatory and Immunomodulatory Properties Of Medicinal Plant Products- Abdelhakim Bouyahya and Youssef Bakri
- Introduction
- Medicinal Plants Bioactive Molecules
- Terpenes
- Polyphenols
- Flavonoids
- Alkaloids
- Anti-Inflammatory Effects of Medicinal Plant Products
- Immunomodulatory Effects of Medicinal Plant Products
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 2 Helminth Therapy: a New Tool for Treatment of Allergic
- Diseases
- Dalia S. Ashour
- Introduction
- Hygiene Hypothesis
- Allergy
- Allergic Immune Response
- Host Immune Response to Helminth Infection
- Regulatory Mechanisms in Helminth Infection
- Immune Response for Combined Helminth Infections and Allergic Diseases
- Positive Association of Some Helminths with Allergic Diseases
- Factors Affecting the Effect of Helminth Infection on Allergic Diseases
- Different Helminths Species
- Type of the Host (Definitive Vs Accidental Host)
- Timing and Chronicity of Infection
- Intensity of Infection
- Host Genetics
- The Concept of Helminth Therapy
- Role of Helminth-Derived Products in Protection from Allergy
- General Hdp
- Cytokine Homologue
- Protease Inhibitors
- Es-62
- Species-Specific Hdp
- Ascaris Suum-Derived Antigens
- Current Status of Helminthic Therapy in Allergic Diseases
- Challenges of Helminth Therapy
- Ethical Considerations
- Practical Considerations
- Conclusions and Future Perspectives
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 3 an Overview of Anti-Allergic Medications in Paediatric
- Population
- Edwin Dias, and Anusha Leah Dias
- Introduction
- Drugs Used in Allergic Diseases
- H1 Antihistamines
- Leukotriene Inhibitors
- Th2 Cytokine Inhibitors
- Corticosteroids
- Types of Medications
- Corticosteroids
- Antihistamines
- Other Allergy Medications
- Immunotherapy
- Seasonal Allergy Treatments
- Allergic Diseases Treatment
- Allergic Rhinitis
- Allergic Conjunctivitis
- Atopic Dermatitis
- Food Allergy
- Anti-Allergic Medications
- Bronchial Asthma
- Antiallergic Medications
- Management of Steroid-Resistant Asthma
- Newer Drugs in Asthma Control
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 4 In-Silico Approaches in Drug Discovery and Design Of
- Anti-Allergic Agents
- Purusottam Banjare, Ajay Singh Sarthi, Jagadish Singh and Partha Pratim Roy
- Introduction
- Pathophysiology of Allergy Reaction
- Targets Associated with Allergy
- Histamine
- Leukotrienes and Lipoxygenases (Loxs):
- Thromboxane A2
- Interleukin
- Mast Cells
- Other Targets
- In Silico Methods Used in Drug Discovery Process
- Ligand Based Approaches
- Qsar
- Pharmacophore Mapping
- Comfa
- Structure Based Approaches
- Homology Modelling
- Molecular Docking
- In Silico Approaches to Different Targets of Allergy
- Histamine
- Leukotrienes and Lipoxygenases
- Thromboxane A2
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgement
- References
Chapter 5 Microbiota and Allergy: Possible Interventions
- Suparna Roy Sarkar, Dharmik Joshi and Sugato Banerjee
- Gut Microbiota as Immune Modulators in Allergy
- Gut Microbiota in Skin Allergy
- Lung Microbiome in Asthma
- Skin Microbiota in Skin Allergy
- Acne
- Psoriasis
- Atopic Dermatitis
- Probiotics
- Prebiotics
- Synbiotics
- Probiotics, Prebiotics and Synbiotics in Allergic Diseases
- Asthma
- Atopic Dermatitis
- Acne
- Allergic Rhinitis
- Food Allergy
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- In Silico Approaches of Different Non Target Anti-Allergic Agents
- Subject Index
Author
- Atta-ur-Rahman
