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Pregnancy and Anti-Infective Agents

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    Book

  • November 2020
  • Bentham Science Publishers Ltd
  • ID: 5215261
This concise clinical reference facilitates health consultants and professionals for determining treatment options for some common prenatal and postpartum infections during pregnancy and the puerperium in patients.

Key Features
  • Presents 9 organized, easy to read chapters on anti-infective agents for pregnant patients
  • Covers pharmacokinetics and pharmacodynamics of relevant anti-infective agents
  • Includes information on classification and safety of anti-infective agents
  • Includes treatment of urinary tract infections
  • Covers medications for sexually transmitted diseases, including a complete section dedicated to HIV medication
  • Provides information about vulvovaginal infections
  • Covers the treatment of toxoplasmosis in pregnancy
  • Innovates with information about herbal remedies for infection for patients during pregnancy and breastfeeding.

Pregnancy and Anti-Infective Agents is therefore, a valuable handbook that enables quick consultation on safe antibiotics for the treatment of a variety of infections in pregnancy.

Table of Contents

Preface

List of Contributors

Chapter 1 Infections in Pregnancy: Maternal and Fetal Risks
  • Background
  • Viral Infections
  • Rubella
  • Cytomegalovirus
  • Herpes Simplex Virus
  • Varicella Zoster Virus
  • Parvovirus B19
  • Influenza
  • Zika
  • Human Immunodeficiency Virus
  • Bacterial Infections
  • Syphilis
  • Group B Streptococcus
  • Other Infections
  • Toxoplasmosis
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 2 Pharmacodynamics and Pharmacokinetics of Anti-Infective
  • Agents in Pregnant Women
  • Background
  • Pharmacological Considerations and Physiological Changes
  • During Pregnancy
  • Pharmacokinetics and Pharmacodynamics
  • Drug Absorption
  • Drug Distribution
  • Drug Metabolism
  • Elimination of Drugs
  • Changes in the Urinary Tract During Pregnancy
  • Classification of Used Drugs in Pregnancy
  • Classification According to the Categories of Risk of Drugs in Pregnancy
  • Antibiotics and Other Anti-Infectious Agents in Pregnancy
  • Betalactam and Related Antibiotics
  • Penicillins
  • Cephalosporins
  • Macrolides
  • Nitrofurans
  • Aminoglycosides
  • Lincosamides
  • Janaína Crispim Freitas, Diana Gonçalves Dantas, Jaline Pessoa Cavalcante, Júlia Alencar
  • De Medeiros, Juliana Davim Ferreira Gomes and Ricardo Ney Cobucci
  • Neidmar Da Mata, Letícia Jales, Ada Isa Custódio, Mayara Maria Sales Monteiro
  • Wenddy De Lima Cavalcanti Lacerda and Raniere Da Mata Moura
  • Clindamycin
  • Quinolones
  • Antifungals with Application in Pregnancy
  • Metronidazole
  • Clotrimazole
  • Miconazole
  • Antivirals
  • Acyclovir
  • Penciclovir
  • Trichloroacetic Acid (Tca)
  • Zidovudine/Lamivudine/Nevirapine
  • Conclusions
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 3 Classification and Safety of Anti-Infective Agents During
  • Pregnancy
  • Background
  • Antimicrobials
  • Penicillins
  • Cephalosporins
  • Imipenem
  • Vancomycin
  • Tetracyclines
  • Chloramphenicol
  • Aminoglycosides
  • Macrolide
  • Sulphonamides
  • Quinolones
  • Lincosamides
  • Rifampicin
  • Others
  • Metronidazole
  • Nitrofurantoin
  • Phosphomycin
  • Antifungals
  • Antiviral Agents
  • Herpesviridae
  • Antiretrovirals
  • Anti-Influenza
  • Antimalarial Agents
  • Anthelmintic Agents
  • Ivermectin
  • Benzimidazole (Bzs)
  • Praziquantel (Fda Category B)
  • Conclusion
  • Consent for Publication
  • Jaline De Melo Pessoa Cavalcante, Fernanda Coêlho Paiva, Janaína Crispim Freitas
  • Diana Gonçalves Dantas, Luana Paiva Souza and Ricardo Ney Cobucci
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 4 Treatment of Urinary Tract Infections in Pregnancy
  • Background
  • Pathogenesis
  • Risk Factors
  • Microbiology
  • Classification of Utis
  • Asymptomatic Bacteriuria
  • Acute Cystitis
  • Acute Pyelonephritis
  • Antibiotic Safety in Pregnancy
  • Antibiotics in Breastfeeding
  • Non Antibiotic Measures
  • Recurrent Utis
  • Prevention of Recurrent Utis
  • Conclusions
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 5 Anti-Infective Agents for Sexually Transmitted Infections
  • In Pregnancy
  • Background
  • Viral Genital Infections
  • Human Papillomavirus (Hpv)
  • Herpes Simplex Vírus (Hsv)
  • Human Immunodeficiency Virus (Hiv)
  • Protease Inhibitor
  • Integrase Inhibitor Regimen
  • Human T-Lymphotropic Virus (Htlv)
  • Hepatitis B Virus (Hbv)
  • Hepatitis C Virus (Hcv)
  • Zika Virus (Zikv)
  • Bacterial Genital Infections
  • Neisseria Gonorrhoeae
  • Chlamydia Trachomatis (Ct)
  • Syphilis
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References
  • Ayane Cristine Alves Sarmento, Antônio Carlos Queiroz De Aquino, Michelly Nóbrega
  • Monteiro and Iaponira Da Silva Figueiredo Vidal
  • Ana Paula Costa, Ayane Cristina Sarmento, Maria Da Conceição Cornetta and Ana
  • Katherine Gonçalves
  • Background
  • Antiretrovirals for Hiv Infected Pregnant Woman
  • Nucleos(T)Ide Analog Reverse-Transcriptase Inhibitors (Nrti)
  • Class Representatives
  • Zidovudine or Azidotimidine (Zdv or Azt)
  • Tenofovir Disoproxil Fumarate (Tdf)
  • Abacavir (Abc)
  • Lamivudine (3Tc)
  • Emtricitabine (Ftc)
  • Non-Nucleoside Analog Reverse-Transcriptase Inhibitors (Nnrti) 117
  • Class Representatives
  • Efavirenz (Efv)
  • Nevirapine (Nvp)
  • Etravirine (Etv)
  • Rilpivirine (Rpv)
  • Doravirine (Dor)
  • Protease Inhibitors (Pi)
  • Class Representatives
  • Atazanavir (Atv)
  • Darunavir (Drv)
  • Ritonavir (Rtv)
  • Integrase Inhibitors (Ini)
  • Class Representatives
  • Dolutegravir (Dtg)
  • Raltegravir (Ral)
  • Entry and Fusion Inhibitors
  • Class Representatives
  • Maraviroc (Mrv)
  • Enfuvirtide (T20)
  • Considerations About Use of Antiretrovirals Intrapartum And
  • After Delivery
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 7 Anti-Infective Agents for Vulvovaginal Infections in Pregnancy
  • Background
  • Genital Changes During Pregnancy
  • Bacterial Vaginosis
  • Trichomonas Vaginalis
  • Candidiasis
  • Conclusion
  • Consent for Publication
  • Conflict of Interest

Chapter 6 Anti-Infective Agents for Hiv in Pregnancy
  • Igor Thiago Queiroz, Themis Rocha Souza, Juliana Mendonça Freire, Alexandre Estevam
  • Montenegro Diniz and Matheus De Araújo Duda
  • Iaponira Da Silva Figueiredo Vidal, Ana Paula Costa, Ana Katherine Gonçalves and Maria
  • Da Conceição De Mesquita Cornetta
  • Acknowledgements
  • References

Chapter 8 Anti-Infective Agents for Toxoplasmosis in Pregnancy
  • Introduction
  • Screening and Diagnosis
  • Maternal (Prenatal) Treatment
  • Spiramycin
  • Pyrimethamine, Sulfadiazine, and Folinic Acid (Psf)
  • Other Potential Treatment Options
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 9 Natural Anti-Infective Remedies in Pregnancy
  • Silvana Maria Zucolotto*
  • Background
  • Pregnancy and Natural Remedies
  • Natural Anti-Infective Remedies in Pregnancy
  • Cranberry (Vaccinium Macrocarpon, Vaccinium Oxycoccos)
  • Echinacea
  • Barberry (Berbery Vulgaris)
  • Hydrastis Canadenses
  • Red Raspberry (Rubus Idaeus)
  • Garlic (Allium Sativum L. )
  • Conclusion
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References
  • Igor Thiago Queiroz and Carolina A. D. Santos
  • Subject Index

Author

  • Ricardo Ney Cobucci