Millions of people worldwide are affected by various eye diseases, and given the anatomic and physiologic barriers of the eye, effective delivery of ocular therapeutics can be challenging. The majority of ocular pharmaceutical treatments are delivered as topical formulations which tend to be highly inefficient and difficult to administer properly. Injectable formulations are available to a lesser extent and can be associated with serious side effects and require administration by a medical professional.
Fortunately there are more than 50 companies developing improved ocular delivery systems which provide benefits such as sustained release, enhanced penetration into ocular tissue, accurate dosing, and ease of administration. These companies range from emerging start-ups with preclinical projects to established specialty and multinational companies with late-stage pipeline products. There are also numerous University research groups innovating in the ocular space. Collectively, they have more than 80 novel ocular formulations and products in various stages of development for indications such as glaucoma, uveitis, macular degeneration, and dry eye disease.
This report provides an overview of the ocular drug delivery market and in-depth profiles of innovative formulation and device technologies currently in development. Additionally, the report highlights the various company and University technologies which are available for partnering. Examples of novel technologies presented: “smart” eye drop devices, punctal plugs, drug-eluting lenses, mucoadhesive nanoparticles and micelles, episcleral implants, micro-injectors, antibody biopolymer conjugates, and sustained release implants and depots.
Report Contents:
Eye Diseases
- Overview and prevalence data
- Age-related macular degeneration
- Macular edema and diabetic retinopathy
- Glaucoma
- Inflammatory conditions
Market Overview
- US Ophthalmic Market by Product Type
- Top-selling prescription ophthalmic products, 2019
- Key players
- Ophthalmic revenues and drug delivery products
Ophthalmic Drug Delivery Landscape
- Non-invasive delivery technologies
- Eye drops/solutions, ocular inserts, punctal plugs, drug-loaded lenses
- Invasive delivery technologies
- Intravitreal injections, implants, suprachoroidal injectors
- Approved ocular drug delivery products (US)
- Ocular drug delivery pipeline
- Glaucoma
- Uveitis and macular edema
- Ocular inflammation
- Age-related macular degeneration
- Dry eye disease
- Novel therapeutics and indications
- Development opportunities
- Future perspectives
Technology Profiles – 50+ Companies
- Examples of companies included:
- Aerie Pharmaceuticals
- AesculaTech
- Amorphex Therapeutics
- Clearside Biomedical
- Congruence Medical
- Eximore Ltd.
- EyeGate Pharma
- Eyenovia
- EyePoint Pharmaceuticals
- Glaukos
- Graybug Vision
- iVeena Delivery Systems
- iView Therapeutics
- Kala Pharmaceuticals
- Kedalion Therapeutics
- Kodiak Biosciences
- Leo Lens Pharma
- Mati Therapeutics
- MuPharma
- Nemera
- Novaliq
- Ocular Therapeutix
- Oculis
- PolyActiva
- Re-Vana Therapeutics
- Santen Pharmaceuticals
- Sun Ophthalmics
- TALLC
- TearClear
- VisusNano
For each company profiled, the following information is provided:
- Technology description
- Development stage
- Competitive advantage
- Patents
- Company description
- Partnerships
- Contact information for partnering
Reasons to buy:
- Identify enabling delivery systems or devices for pipeline drugs
- Scout enhancing technologies for LCM of marketed ophthalmic drugs
- Understand the key players and therapeutic segments
- Obtain product and technology information for launched ophthalmics
- View pipeline details for novel ocular formulations in development
- Discover product and technology licensing opportunities
Table of Contents
Introduction
Companies Mentioned
- 20/20 OptimEyes
- 3T Ophthalmics
- Abbvie
- Aciont
- Aerie Pharmaceuticals
- AesculaTech
- Amorphex Therapeutics
- BioLight Life Sciences
- CIS Pharma
- Clearside Biomedical
- Congruence Medical
- DelSiTech
- Eximore
- EyeCRO
- EyeGate Pharma
- EyePoint Pharmaceuticals
- Eyenovia
- Eyevensys
- Glaukos
- Glint Pharmaceuticals
- Graybug Vision
- Integral Ophthalmics
- Kala Pharmaceuticals
- Kedalion Therapeutics
- Kodiak Biosciences
- LayerBio
- Leo Lens Pharma
- MC2 Therapeutics
- Mati Therapeutics
- MuPharma
- Nemera
- Neurotech Pharmaceuticals
- Novaliq
- Novel Aerosol & Eye Drop Devices
- OcuJect
- OcuMedic
- Ocular Therapeutix
- Oculis
- PolyActiva
- Re-Vana Therapeutics
- Roche
- Santen Pharmaceuticals
- Sun Ophthalmics
- TALLC
- TLC Bio
- TearClear
- VisusNano
- Zeteo Biomedical
- iVeena Delivery Systems
- iView Therapeutics