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Gastritis - Pipeline Review, H2 2020

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    Drug Pipelines

  • 93 Pages
  • November 2020
  • Region: Global
  • Global Markets Direct
  • ID: 5229462
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Summary

The publisher's latest Pharmaceutical and Healthcare disease pipeline guide Gastritis - Pipeline Review, H2 2020, provides an overview of the Gastritis (Gastrointestinal) pipeline landscape.

Gastritis is characterized by inflammation or swelling of the lining of the stomach. Acute gastritis lasts for a short period of time while chronic gastritis lasts for a long period of time (months to years). Gastritis can be caused by medications such as ibuprofen, aspirin, naproxen on long periods of consumption, excess intake of alcohol, Helicobacter pylori infection, certain autoimmune disorders, bile reflux, substance abuse (cocaine), consumption of corrosive or caustic substances such as poisons, extreme stress, viral infections and trauma. The symptoms of gastritis may include loss of appetite, nausea and vomiting, abdominal pain and black stools. Treatment includes use of antacids, Histamine 2 (H2) antagonists and proton pump inhibitors.

Report Highlights

The publisher's Pharmaceutical and Healthcare latest pipeline guide Gastritis - Pipeline Review, H2 2020, provides comprehensive information on the therapeutics under development for Gastritis (Gastrointestinal), complete with analysis by stage of development, drug target, mechanism of action (MoA), route of administration (RoA) and molecule type. The guide covers the descriptive pharmacological action of the therapeutics, its complete research and development history and latest news and press releases.

The Gastritis (Gastrointestinal) pipeline guide also reviews of key players involved in therapeutic development for Gastritis and features dormant and discontinued projects. The guide covers therapeutics under Development by Companies /Universities /Institutes, the molecules developed by Companies in Phase III, Phase II, Phase I, Preclinical and Discovery stages are 3, 2, 3, 4 and 1 respectively.

Gastritis (Gastrointestinal) pipeline guide helps in identifying and tracking emerging players in the market and their portfolios, enhances decision making capabilities and helps to create effective counter strategies to gain competitive advantage. The guide is built using data and information sourced from the publisher’s proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations and featured press releases from company/university sites and industry-specific third party sources. Additionally, various dynamic tracking processes ensure that the most recent developments are captured on a real time basis.

Note: Certain content/sections in the pipeline guide may be removed or altered based on the availability and relevance of data.

Scope
  • The pipeline guide provides a snapshot of the global therapeutic landscape of Gastritis (Gastrointestinal).
  • The pipeline guide reviews pipeline therapeutics for Gastritis (Gastrointestinal) by companies and universities/research institutes based on information derived from company and industry-specific sources.
  • The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
  • The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
  • The pipeline guide reviews key companies involved in Gastritis (Gastrointestinal) therapeutics and enlists all their major and minor projects.
  • The pipeline guide evaluates Gastritis (Gastrointestinal) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
  • The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
  • The pipeline guide reviews latest news related to pipeline therapeutics for Gastritis (Gastrointestinal)

Reasons to Buy
  • Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
  • Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
  • Find and recognize significant and varied types of therapeutics under development for Gastritis (Gastrointestinal).
  • Classify potential new clients or partners in the target demographic.
  • Develop tactical initiatives by understanding the focus areas of leading companies.
  • Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
  • Formulate corrective measures for pipeline projects by understanding Gastritis (Gastrointestinal) pipeline depth and focus of Indication therapeutics.
  • Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
  • Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.

Table of Contents

IntroductionGastritis - Overview
Gastritis - Therapeutics Development
  • Pipeline Overview
  • Pipeline by Companies
  • Products under Development by Companies

Gastritis - Therapeutics Assessment
  • Assessment by Target
  • Assessment by Mechanism of Action
  • Assessment by Route of Administration
  • Assessment by Molecule Type

Gastritis - Companies Involved in Therapeutics Development
  • Addpharma Inc
  • Allakos Inc
  • CalyGene Biotechnology Inc
  • GNT Pharma Co Ltd
  • Kukje Pharmaceutical Industry Co Ltd
  • Kyowa Kirin Co Ltd
  • Otsuka Holdings Co Ltd
  • Recce Pharmaceuticals Ltd
  • RedHill Biopharma Ltd
  • Trio Medicines Ltd

Gastritis - Drug Profiles
AAD-2004 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

AD-203 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

AD-206 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

benralizumab - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

CG-20043 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

INT-2150 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

lirentelimab - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ND-07 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

netazepide - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

ondansetron hydrochloride CR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

rebamipide SR - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

RECCE-327 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

RECCE-435 - Drug Profile
  • Product Description
  • Mechanism Of Action
  • R&D Progress

Gastritis - Dormant Projects
Gastritis - Product Development Milestones
  • Featured News & Press Releases
  • Oct 26, 2020: Results from prospective prevalence study indicate that eosinophilic gastritis and eosinophilic duodenitis may be significantly underdiagnosed
  • Oct 26, 2020: Allakos announces results from a phase 1 study of subcutaneously administered lirentelimab (AK002)
  • Oct 21, 2020: Anti-Siglec-8 Antibody trial shows promise for treating Eosinophilic gastritis and duodenitis
  • Oct 21, 2020: Allakos announces publication of results from the phase 2 study of lirentelimab (AK002) in patients with Eosinophilic Gastritis and/or Eosinophilic Duodenitis (ENIGMA) in the New England Journal of Medicine
  • Jun 03, 2020: Allakos initiates patient recruitment for AK002 registrational studies
  • May 04, 2020: Allakos announces positive interim results from an open-label extension study of Antolimab (AK002) in patients with eosinophilic gastritis and/or eosinophilic duodenitis
  • Apr 21, 2020: Allakos announces multiple presentations related to eosinophil and mast cell-driven diseases at the 2020 DDW Annual Meeting
  • Mar 24, 2020: Allakos announces positive phase 1 results with Antolimab (AK002) in Mast Cell Gastrointestinal Disease
  • Oct 28, 2019: Allakos Announces Multiple Presentations from Its Eosinophilic Gastrointestinal Diseases Program at the American College of Gastroenterology (ACG) 2019 Annual Scientific Meeting
  • Aug 05, 2019: Allakos announces AK002 met all prespecified primary and secondary endpoints in phase 2 randomized, double-blind, placebo-controlled study in patients with eosinophilic gastritis (EG) and/or eosinophilic gastroenteritis (EGE)
  • Oct 08, 2018: Allakos presents data from its eosinophilic gastrointestinal diseases program at the American College of Gastroenterology (ACG) 2018 Annual Scientific Meeting
  • Jun 19, 2017: RedHill Biopharma to Host Conference Call on Successful Phase III Top-Line Results with BEKINDA for Acute Gastroenteritis
  • Feb 13, 2017: RedHill Biopharma Announces Enrollment of Last Patient in BEKINDA Phase III Study for Acute Gastroenteritis
  • Nov 03, 2016: RedHill Biopharma Provides Update on Ongoing Phase III and Phase II studies with BEKINDA and Expected Timing of Top-Line Results
  • Mar 02, 2015: Positive Bioavailability Studies of RedHill's BEKINDA to be Presented at the 2015 American Society for Clinical Pharmacology and Therapeutics Meeting

Appendix
  • Methodology
  • Coverage
  • Secondary Research
  • Primary Research
  • Expert Panel Validation
  • Contact
  • Disclaimer

List of Tables
  • Number of Products under Development for Gastritis, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Products under Development by Companies, H2 2020
  • Number of Products by Stage and Target, H2 2020
  • Number of Products by Stage and Mechanism of Action, H2 2020
  • Number of Products by Stage and Route of Administration, H2 2020
  • Number of Products by Stage and Molecule Type, H2 2020
  • Gastritis - Pipeline by Addpharma Inc, H2 2020
  • Gastritis - Pipeline by Allakos Inc, H2 2020
  • Gastritis - Pipeline by CalyGene Biotechnology Inc, H2 2020
  • Gastritis - Pipeline by GNT Pharma Co Ltd, H2 2020
  • Gastritis - Pipeline by Kukje Pharmaceutical Industry Co Ltd, H2 2020
  • Gastritis - Pipeline by Kyowa Kirin Co Ltd, H2 2020
  • Gastritis - Pipeline by Otsuka Holdings Co Ltd, H2 2020
  • Gastritis - Pipeline by Recce Pharmaceuticals Ltd, H2 2020
  • Gastritis - Pipeline by RedHill Biopharma Ltd, H2 2020
  • Gastritis - Pipeline by Trio Medicines Ltd, H2 2020
  • Gastritis - Dormant Projects, H2 2020

List of Figures
  • Number of Products under Development for Gastritis, H2 2020
  • Number of Products under Development by Companies, H2 2020
  • Number of Products by Top 10 Targets, H2 2020
  • Number of Products by Stage and Top 10 Targets, H2 2020
  • Number of Products by Top 10 Mechanism of Actions, H2 2020
  • Number of Products by Stage and Top 10 Mechanism of Actions, H2 2020
  • Number of Products by Top 10 Routes of Administration, H2 2020
  • Number of Products by Stage and Top 10 Routes of Administration, H2 2020
  • Number of Products by Top 10 Molecule Types, H2 2020
  • Number of Products by Stage and Top 10 Molecule Types, H2 2020

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Addpharma Inc
  • Allakos Inc
  • CalyGene Biotechnology Inc
  • GNT Pharma Co Ltd
  • Kukje Pharmaceutical Industry Co Ltd
  • Kyowa Kirin Co Ltd
  • Otsuka Holdings Co Ltd
  • Recce Pharmaceuticals Ltd
  • RedHill Biopharma Ltd
  • Trio Medicines Ltd