The Vast Majority of the Global Cord Blood Market is Now Controlled by the World’s 10 Largest Cord Blood Banking Operators
The first transplant using cord blood-derived hematopoietic stem cells (HSCs) occurred in October 1988. Since then, significant advancements have been made in researching umbilical cord blood-derived hematopoietic and progenitor cells. To date, over 40,000 umbilical cord blood transplants (UCBTs) have been performed worldwide, treating a variety of conditions, including hematologic, metabolic, immunologic, neoplastic, and neurologic disorders. Public cord blood banks now store more than 800,000 units, while private banks house over 8.1 million units globally.
Cord blood storage began as a commercial service in the early 1990s, but cord tissue storage only became available commercially in 2008, with HealthBanks Biotech Company Ltd. in Taiwan leading the way. Hong Kong's HealthBaby and Cryolife also introduced the service in 2009. In the U.S., Cord Blood Registry (CBR) was the first private company to offer cord tissue storage in July 2010. Today, nearly all U.S. cord blood banks and about one-third of global cord blood banks provide cord tissue storage.
LifebankUSA pioneered placental blood storage in the U.S. in 2006 and introduced placental tissue storage in 2011. Americord Registry followed with placental tissue banking in September 2017. Internationally, several cord blood banks now offer placental blood and tissue storage. Some have diversified into other stem cell sources, such as dental pulp stem cells. For example, DentCell, managed by Cryoholdco, Latin America's largest cord blood banking consolidator, focuses on dental pulp stem cells. Additionally, a few cord blood banks are expanding into adipose-derived stem cell storage.
Recent years have seen record levels of merger and acquisition (M&A) activity in the cord blood industry. The market is now predominantly controlled by a handful of large cord blood banking operators, including Global Cord Blood Corporation (GCBC), Cord Blood Registry (owned by CooperSurgical), ViaCord, Cryo-Cell International, Cordlife Group, VCANBIO Cell & Gene Engineering Corporation, Lifecell International, Cryoholdco, and Medipost. This consolidation is notable given the rapid growth of the industry in the early 2000s. Significant consolidation has occurred in the U.S., Europe, Asia, and Latin America:
- PBKM FamiCord has acquired most of the European market, including merging with it largest competitor Vita34 and acquiring assets from Cryo-Save AG's 2019 bankruptcy.
- CooperSurgical has consolidated reproductive, newborn stem cell, and genetic services within the U.S., managing at least 1.1 million units.
- Cryoholdco has amassed stem cell banking assets across Latin America, including four in Mexico, two in Colombia, two in Brazil, and one in Peru, totaling an estimated 300,000 units.
- Sanpower Group dominates the Asian market through its ownership of Global Cord Blood Corporation and other assets across Southeast Asia, controlling over 1.2 million units.
- India, with its burgeoning population of 1.4 billion, rivals China in size, making up approximately 36% of the world’s 7.8 billion people. LifeCell International is the leading stem cell bank in India, storing over 320,000 units.
The cord blood industry has also seen substantial advancements in perinatal tissue applications, including umbilical cord blood, umbilical cord tissue, placental blood and tissue, and amniotic fluid. This has led to a proliferation of storage services for these biomaterials.
Many cord blood banks have expanded their offerings to include:
- Reproductive and assisted fertility services
- Pre- and post-natal genetic testing
- Cell therapy product development
The Cord Blood and Tissue Market is composed of several segments, including:
- Storage (Cryopreservation): Revenue comes from cord blood collection, processing, and long-term storage contracts. Investment firms have recently entered this market, acquiring stakes in cord blood and tissue banks.
- Transplantation Medicine: There is a robust market for cord blood use in treating diseases such as leukemia and sickle cell disease. Over 40,000 UCB transplants have been performed, with more than 80 medical conditions approved for treatment with cord blood-derived stem cells.
- Regenerative Medicine: Research into the use of cord blood and tissue in regenerative medicine is expanding. Clinical trials are exploring treatments for neurological disorders like cerebral palsy, autism spectrum disorder, and hearing loss. RheinCell Therapeutics, now owned by Catalent, has achieved GMP certification for manufacturing cord blood-derived iPSCs. The FDA approved the world’s first expanded cord blood cell therapy, Omisirge, in April 2023.
- Research Supply Products: This segment includes cells, tissues, reagents, and kits. Major market leaders such as Lonza, STEMCELL Technologies, and AllCells are now offering cord blood products for research purposes.
This report provides a comprehensive analysis, including:
- The number of cord blood and tissue units cryopreserved in public and private banks worldwide.
- The number of hematopoietic stem cell transplants performed globally using cord blood cells.
- The use of cord blood cells in regenerative medicine clinical trials.
- The decline in cord blood utilization for HSCT since 2005.
- Emerging technologies influencing public cord blood banks' financial sustainability.
- Future prospects for companion products derived from cord blood.
- The evolving landscape of the cord blood and tissue banking market.
- Expansion and extension of services by cord blood banks.
- Economic models and cost analyses for public and private cord blood banks.
- Profit margins and pricing for processing and storage in private banks.
- Rates per cord blood unit in the U.S. and Europe.
- Indications for cord blood-derived HSCs in transplantation medicine.
- Diseases targeted by cord blood-derived MSCs in regenerative medicine.
- Cord blood processing technologies and the dominant market leaders offering them.
- Clinical trials, published scientific papers, and funding for cord blood research.
- Patents for cord blood, cord tissue, and placental products.
- Transplantation data from various cord blood registries.
Key questions addressed in this market report include:
- Strategies to improve the financial stability of private cord blood banks.
- Strategies to improve the financial stability of public cord blood banks.
- Companion products being developed from cord blood and tissue.
- Costs for processing and storing cord blood.
- Market value of cryopreserved cord blood units upon release.
- Financial losses commonly incurred by public cord blood banks.
- Net profit margins for private cord blood banks.
- Pricing for processing and storage services in private banks.
- Rates per cord blood unit in the U.S. and Europe.
- Revenues from cord blood sales for major banks.
- Accreditation systems for cord blood and tissue banks.
- Comparative merits of cord blood processing technologies.
- Strategies to increase cord blood utilization in transplantation.
- Preferred TNC counts for transplantation.
- Number of registered clinical trials using cord blood and cord tissue.
- Clinical trials studying ex vivo expansion of cord blood and a recent product approval.
- Annual number of matching and mismatching cord blood transplantations.
- Share of cord blood transplants compared to bone marrow and peripheral blood transplants.
- Likelihood of finding matching allogeneic cord blood units by ethnicity.
- Top countries for cord blood donations.
- Diseases targeted by cord blood and tissue-derived MSCs in clinical trials.
- Breakdown of clinical trials investigating cord blood-derived cells by geography, study type, phase, and funding.
- Breakdown of trials exploring cord tissue-derived cells.
- Current patent rates and leading jurisdictions for cord blood, cord tissue, and placental patents.
- Leading inventors, applicants, and owners of perinatal stem cell patents.
- Number of units stored by public and private banks worldwide.
- Leading cord blood banks by region and storage volume.
- Market sizes for cord blood and tissue banking and therapeutic applications.
This global strategic report offers a thorough analysis of the cord blood and tissue banking market, providing insights into current trends, future projections, and key players in the industry. It is an essential resource for those seeking a comprehensive understanding of the market without investing excessive time in research.
Table of Contents
Companies Mentioned
- AllCells
- AlphaCord
- Americord Registry, Inc.
- Angiocrine Bioscience
- Anja Health Personalized Cord Blood Banking
- Anthony Nolan
- Baylx, Inc.
- Be The Match
- Biocell Center
- BioEden
- BioIntegrate, LLC
- Bloodworks Northwest
- California Umbilical Cord Collection Program
- Carolinas Cord Blood Bank (CCBB)
- Celaid Therapeutics
- Celebration Stem Cell Centre (CSCC)
- Cell Care
- Cellenkos, Inc.
- Cells4Life Group LLP
- CellSave Arabia
- Celularity, Inc.
- Center for International Blood and Marrow Transplant Research (CIBMTR)
- CHOC Blood Bank
- Cleveland Cord Blood Center
- ClinImmune Cell and Gene Therapy
- Cord Blood Bank of Arkansas (CBBA)
- Cord Blood Center Group
- Cord Blood Registry (CBR)
- Cord for Life
- CordLife Group, Ltd.
- CordVida
- Crioestaminal
- Cryo-Cell International, Inc.
- CryoCyte, LLC
- CryoHoldco LATAM
- Cryopoint
- Cryoviva Biotech Pvt., Ltd.
- DKMS gGMBH
- Duke University School of Medicine
- European Society for Blood and Bone Marrow Transplantation (EBMT)
- Ever Supreme Bio Technology, Co., Ltd.
- ExCellThera
- FamiCord Group
- Fate Therapeutics, Inc.
- Future Health
- Gamida Cell
- GeneCell
- Global Cord Blood Corporation (GCBC)
- Glycostem Therapeutics
- Hawaii Cord Blood Bank
- HealthBaby
- HealthBanksUSA
- HEMAFUND
- Hemogenyx Pharmaceuticals
- IMMUNIQUE
- Insception LifeBank
- JP McCarthy Cord Stem Cell Bank
- Kangstem Biotech, Co., Ltd.
- LifebankUSA
- LifeCell International Pvt. Ltd.
- Life Line Stem Cell
- LifeSouth Cord Blood Bank
- Magenta Therapeutics
- Maze Cord Blood
- Medipost, Co., Ltd.
- Mesoblast, Ltd.
- MD Anderson Cord Blood Bank
- Mesoblast, Ltd.
- MiracleCord, Inc.
- Mononuclear Therapeutics, Ltd.
- New England Cord Blood Bank, Inc.
- New York Blood Center
- OrganaBio
- PacifiCord
- Plasticell Ltd.
- ReeLabs Pvt. Ltd.
- Restem, LLC
- San Diego Cord Blood Bank
- Saneron CCEL Therapeutics, Inc.
- SmartCells
- SSM Cardinal Glennon Children’s Medical Center
- Stembanc, Inc.
- Stem Cell Cryobank, Inc.
- StemCyte, Inc.
- Throne Biotechnologies, Inc.
- Transcell Biolife
- Upstate Cord Blood Bank
- ViaCord
- Versity, Inc.
- Vita 34 AG
- Vitalant Clinical Services
- World Marrow Donor Association (WMDA)
- Worldwide Network for Blood & Marrow Transplantation (WBMT)
Methodology
The content and statistics contained within the publisher's reports are compiled using a broad range of sources, as described below.
Input Sources
- Clinical Trial Databases (ClinicalTrials.gov, International Clinical Trials Registry Platform, European Union Clinical Trials Register, Chinese Clinical Trial Registry, Others)
- Scientific Publication Databases (PubMed, Highwire Press, Google Scholar)
- Patent Databases (United States Patent and Trade Office, World Intellectual Property Organization, Google Patent Search)
- Grant Funding Databases (RePORT Database, CIRM, MRC, Wellcome Trust - UK, Others)
- Product Launch Announcements (Trade Journals, Google News)
- Industry Events (Google News, Google Alerts, Press Releases)
- Company News (SEC Filings, Investor Publications, Historical Performance)
- Social Analytics (Google Adwords, Google Trends, Twitter, Topsy.com, Hashtagify.me, BuzzSumo.com)
- Interviews with Stem Cell Industry Leaders
Research & Analysis Methodologies
The publisher employs the following techniques for deriving its market research:
- Historical Databases: As the first and only market research firm to specialize in the stem cell industry, the publisher has 13+ years of historical data on each segment of the stem cell the industry. This provides an extremely rare and robust database for establishing market size determinations, as well as making future market predictions.
- Prolific Interviews with Industry Leaders: As the global leader in stem cell industry data, the publisher has interviewed hundreds of leaders from across the stem cell industry, including the CEO of FUJIFILM CDI, FUJIFILM Irvine Scientific, Pluristem Therapies, Celularity, and many others.
- Industry Relationships: The research team and its President/Founder, Cade Hildreth, Chair and present at a wide range of stem cell industry events, including Phacilitate's Advanced Therapies Week, World Stem Cell Summit (WSCS), Perinatal Stem Cell Society Congress, AABB's International Cord Blood Symposium (ICBS), and other events hosted within the U.S. and worldwide.
- Global Integrated Feedback: Because the publisher maintains the world's largest stem cell industry news site that is read by nearly a million unique readers per year and the company has large social media audiences (25.7K+ followers on Linked, 21.2K+ followers on Twitter, and 4.3K+ followers on Facebook), the publisher is able to publish content relevant to the industry and receive immediate feedback/input from a global community of readers. In short, the publisher's data is crowd-sourced from market participants worldwide, including those in diverse geographic regions.
- Preliminary Research: In addition to the interviews described above, the publisher conducts market surveys, executes social media polls, and aggregates market data from stem cell industry announcements, press releases, and corporate filings/presentations.
- Secondary Research: The publisher summarizes, collects and synthesizes existing market research that is relevant to the market area of interest.
- Future Projections: Using the resources described above, the publisher is uniquely positioned to make future projections about market size, market growth by segment, market trends, technology evolution, funding activities (financing rounds, M&A, and IPOs), and importantly, market leadership (market share by company).
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