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Pseudomonas aeruginosa infection - Pipeline Insight, 2024

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    Clinical Trials

  • 50 Pages
  • April 2024
  • Region: Global
  • DelveInsight
  • ID: 5240436
This “Pseudomonas aeruginosa infection - Pipeline Insight, 2024,” report provides comprehensive insights about 10+ companies and 10+ pipeline drugs in Pseudomonas aeruginosa infection pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage

Pseudomonas aeruginosa infection Understanding

Pseudomonas aeruginosa infection: Overview

Pseudomonas aeruginosa infection is caused by bacterium Pseudomonas, a gram-negative bacterium commonly found in the environment e.g., in soil, water, and other moist places. Pseudomonas are opportunistic bacteria which infect individuals who have weak immune system. These bacteria are predominantly responsible for nosocomial infections. Pseudomonas aeruginosa causes urinary tract infections, respiratory system infections, dermatitis, soft tissue infections, bacteremia, bone and joint infections, gastrointestinal infections and a variety of systemic infections, particularly in patients with severe burns and in cancer and AIDS patients who are immunosuppressed. Diagnosing Pseudomonas aeruginosa infection requires laboratory assessments of body fluids such as blood, pus, and urine. Pseudomonas aeruginosa infection can be treated by administration of commonly used antibiotics for instance, gentamicin, tobramycin, and others. However, emergence of multi-drug resistance bacterial strain has made the treatment difficult.

Pseudomonas aeruginosa infection - Pipeline Insight, 2024 report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Pseudomonas aeruginosa infection pipeline landscape is provided which includes the disease overview and Pseudomonas aeruginosa infection treatment guidelines. The assessment part of the report embraces, in depth Pseudomonas aeruginosa infection commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Pseudomonas aeruginosa infection collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Pseudomonas aeruginosa infection R&D. The therapies under development are focused on novel approaches to treat/improve Pseudomonas aeruginosa infection.

Pseudomonas aeruginosa infection Emerging Drugs Chapters

This segment of the Pseudomonas aeruginosa infection report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Pseudomonas aeruginosa infection Emerging Drugs

AP PA02: Armata Pharmaceuticals Armata’s lead drug candidate, AP PA02, is a therapeutic phage cocktail that targets the pathogen P. aeruginosa, to treat serious respiratory infections, with an initial emphasis on cystic fibrosis (CF) patients. Currently, the drug is in phase I b/II trial and is being tested for its tolerability, and safety among humans.

AB 569: Archs Biopharma Arch’s “novel” drug AB 569 is currently being evaluated for the treatment of antibiotic resistant bacterial infection primarily in the lungs caused by P. aeruginosa. The drug has been designated with orphan drug status and follows a different mechanism of action to treat mucoid and non-mucoid pulmonary P. aeruginosainfections.

Pseudomonas aeruginosa infection: Therapeutic Assessment

This segment of the report provides insights about the different Pseudomonas aeruginosa infection drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Pseudomonas aeruginosa infection

There are approx. 10+ key companies which are developing the therapies for Pseudomonas aeruginosa infection. The companies which have their Pseudomonas aeruginosa infection drug candidates in the most advanced stage, i.e. phase I/ II include, Amrata Pharmaceuticals.

Phases

This report covers around 10+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates

Route of Administration

Pseudomonas aeruginosa infection pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Parenteral
  • intravitreal
  • Subretinal
  • Topical.
  • Molecule Type

Products have been categorized under various Molecule types such as

  • Monoclonal Antibody
  • Peptides
  • Polymer
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Pseudomonas aeruginosa infection: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Pseudomonas aeruginosa infection therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Pseudomonas aeruginosa infection drugs.

Pseudomonas aeruginosa infection Report Insights

  • Pseudomonas aeruginosa infection Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Pseudomonas aeruginosa infection Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Pseudomonas aeruginosa infection drugs?
  • How many Pseudomonas aeruginosa infection drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Pseudomonas aeruginosa infection?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Pseudomonas aeruginosa infection therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Pseudomonas aeruginosa infection and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Amrata Pharmaceuticals
  • Archs Biopharma
  • Qpex Biopharma
  • Polyphor
  • Nosopharm
  • Pfizer

Key Products

  • AP PA02
  • AB 569
  • QPX7728
  • Murepavadin
  • NOSO A4
  • PF-06482077


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Table of Contents

IntroductionExecutive Summary
Pseudomonas aeruginosa infection: Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Pseudomonas aeruginosa infection - Analytical Perspective
In-depth Commercial Assessment
  • Pseudomonas aeruginosa infection companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Pseudomonas aeruginosa infection Collaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  • Comparative Analysis
Drug Name: Company Name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  • Comparative Analysis
Drug Name: Company Name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
  • Comparative Analysis
AP PA02: Amrata Pharmaceuticals
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
  • Comparative Analysis
AB 569: Arch Biopharma
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  • Comparative Analysis
Pseudomonas aeruginosa infection Key CompaniesPseudomonas aeruginosa infection Key ProductsPseudomonas aeruginosa infection- Unmet NeedsPseudomonas aeruginosa infection- Market Drivers and BarriersPseudomonas aeruginosa infection- Future Perspectives and ConclusionPseudomonas aeruginosa infection Analyst ViewsPseudomonas aeruginosa infection Key CompaniesAppendix
List of Tables
Table 1 Total Products for Pseudomonas aeruginosa infection
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
List of Figures
Figure 1 Total Products for Pseudomonas aeruginosa infection
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Amrata Pharmaceuticals
  • Archs Biopharma
  • Qpex Biopharma
  • Polyphor
  • Nosopharm
  • Pfizer