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Lymphatic Malformations- - Pipeline Insight, 2024

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    Clinical Trials

  • 40 Pages
  • April 2024
  • Region: Global
  • DelveInsight
  • ID: 5262030
UP TO OFF until Dec 31st 2024
This “Lymphatic Malformations- Pipeline Insight, 2024,” report provides comprehensive insights about 4+ companies and 4+ pipeline drugs in Lymphatic Malformations Pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage
Lymphatic MalformationsUnderstanding

Lymphatic Malformations: Overview

Lymphatic malformations are rare, non-malignant masses consisting of fluid-filled channels or spaces thought to be caused by the abnormal development of the lymphatic system. In lymphatic malformations, movement of lymphatic fluid into veins is slow or decreased. This causes extra fluid to collect and to enlarge the lymphatic channels. This results in swelling of the affected area. These malformations are usually apparent at birth or by two years of age. Lymphatic malformations can affect any area of the body (except the brain), but most commonly affect the head and neck. e. Lymphatic malformations, regardless of size, can potentially cause functional impairment of nearby structures or organs and disfigurement of affected areas. Lymphatic malformations have variable appearances. Depending on the size of the abnormal lymphatic channels, they are considered macrocystic, microcystic or a combination of both.

Lymphatic Malformations- Pipeline Insight, 2024 report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Lymphatic Malformations pipeline landscape is provided which includes the disease overview and Lymphatic Malformations treatment guidelines. The assessment part of the report embraces, in depth Lymphatic Malformations commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Lymphatic Malformations collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Lymphatic MalformationsR&D. The therapies under development are focused on novel approaches to treat/improve Lymphatic Malformations.

Lymphatic Malformations Emerging DrugsChapters

This segment of the Lymphatic Malformations Report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Lymphatic Malformations EmergingDrugs
TARA-002: Protara Therapeutics TARA-002 is an investigational cell therapy in development for the treatment of lymphatic malformations (LMs) and non-muscle invasive bladder cancer (NMIBC). When TARA-002 is administered, it is hypothesized that innate and adaptive immune cells within the cyst or tumor are activated and produce a strong immune cascade.TARA-002 has been Granted Orphan Drug and Fast Track Designations by the U.S. FDA. It is currently in phase II stage of development for Lymphatic malformations.

VT30: Vanthera Venthera is developing VT30 topical gel intended to treat Venous and lymphatic malformations . In the third quarter of 2020, Venthera has initiated a first in human phase 1/2 trial of topical VT30 in patients with Venous and lymphaticmalformations.

Lymphatic Malformations: Therapeutic Assessment

This segment of the report provides insights about the different Lymphatic Malformations drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Lymphatic Malformations

There are approx. 4+ key companies which are developing the therapies for Lymphatic Malformations. The companies which have their Lymphatic Malformations drug candidates in the most advanced stage, i.e. phase II include, Protara Therapeutics.

Phases

This report covers around 4+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates

Route of Administration

Lymphatic Malformations pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Oral
  • Intravenous
  • Subcutaneous
  • Topical.
  • Molecule Type

Products have been categorized under various Molecule types such as

  • Peptides
  • Small molecule
  • Gene therapy
  • Product Type
Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Lymphatic Malformations: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Lymphatic Malformations therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Lymphatic Malformations drugs.

Lymphatic Malformations ReportInsights
  • Lymphatic Malformations PipelineAnalysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs
Lymphatic Malformations ReportAssessment
  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Lymphatic Malformations drugs?
  • How many Lymphatic Malformations drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Lymphatic Malformations?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Lymphatic Malformations therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Lymphatic Malformations and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Protara therapeutics
  • Vanthera
  • Cerecor, Inc.

Key Products

  • VT30
  • CERC-006
  • TARA-002


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Table of Contents

IntroductionExecutive Summary
Lymphatic Malformations: Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Lymphatic Malformations- Analytical Perspective
In-depth Commercial Assessment
  • Lymphatic Malformations companies’ collaborations, Licensing, Acquisition -Deal Value Trends
Lymphatic MalformationsCollaboration Deals
  • Company-Company Collaborations (Licensing / Partnering) Analysis
  • Company-University Collaborations (Licensing / Partnering) Analysis
Late Stage Products (Phase III)
  • Comparative Analysis
Drug Name: Company Name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  • Comparative Analysis
TARA-002: Protara Therapeutics
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I/II)
  • Comparative Analysis
VT30: Vanthera
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  • Comparative Analysis
Lymphatic MalformationsKey CompaniesLymphatic MalformationsKey ProductsLymphatic Malformations- Unmet NeedsLymphatic Malformations- Market Drivers and BarriersLymphatic Malformations- Future Perspectives and ConclusionLymphatic MalformationsAnalyst ViewsLymphatic MalformationsKey CompaniesAppendix
List of Tables
Table 1 Total Products for Lymphatic Malformations
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
List of Figures
Figure 1 Total Products for Lymphatic Malformations
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

•Protara therapeutics
•Vanthera
•Cerecor, Inc.