Allergic and Immunologic Diseases. A Practical Guide to the Evaluation, Diagnosis and Management of Allergic and Immunologic Diseases

Table of Contents

Section A: Background 1. A history of allergy and immunology 2. The development of clinical laboratory methods in the diagnosis of human disease 3. Discoveries with significant impact in how we diagnosis and treat diseases 4. Taking an allergy and immunology history and physical 5. Basic genetics and epigenetics for the immunologist and allergist 6. Immunological studies utility and limitations 7. Future developments and how they will impact the practice of medicine

Section B: Diagnosis of allergic diseases 8. Epicutaneous and intradermal skin testing 9. The interpretation of epicutaneous and intradermal skin testing for foods 10. The use of in vitro methods to evaluate allergy 11. Food challenges 12. Testing for the physical urticarias 13. Techniques to evaluate asthma 14. Drug allergy testing 15. Sinus diseases and rhinolaryngoscopy 16. Approach to the rash from an allergy/immunology perspective 17. Patch testing and the evaluation of contact allergy 18. Skin biopsies and their utility 19. The evaluation of mast cell related disorders 20. The evaluation of a patient with urticaria and angioedema 21. Evaluating the patient with eosinophilia or eosinophilic disease 22. Unproven and controversial testing methods in allergy and immunology

Section C: Evaluation of immune function 23. Testing for primary immunodeficiency 24. Testing the innate immune system 25. Testing the adaptive immune system 26. Periodic fever syndromes and autoinflammatory diseases 27. Immunological dysfunction disorders 28. The AIDS workup 29. Basic workup for autoimmune diseases 30. Neuroimmunology 31. Genetic testing

Section D: Treatment of allergic and immunologic diseases 32. Immunotherapy to environmental allergens 33. Drug allergy desensitization methods 34. Oral, sublingual and dermatologic immunotherapy to food allergens 35. Conventional medications for the treatment of allergic diseases 36. The new biologicals in allergy 37. Action plans and quality of life evaluations 38. The treatment of atopic dermatitis 39. The recognition and treatment of anaphylaxis 40. Treatment of venom and other insect allergies 41. Drugs and treatment modalities for itch and hives 42. Integrative medicine in allergy and immunology

Section E: Treatment of immunological disorders 43. Treatment of the patient with PIDD 44. Management of autoinflammatory syndromes and periodic fevers 45. Immunomodulatory pharmaceuticals for the treatment of immune dysfunction 46. Bone marrow transplant for the patient with monogenic PIDD 47. The immunological management of the solid-organ transplant patient 48. Apheresis 49. Pharmaceuticals for AIDS 50. Gene therapy

Authors

Christopher Chang Professor of Medicine and Associate Director, Allergy and Immunology Fellowship Program, Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, California, USA. Dr Chang is the current Medical Director for Pediatric Immunology, Allergy and Rheumatology at Joe DiMaggio Children's Hospital in Florida. At the same time, he serves as Associate Program Director for the Allergy Immunology Fellowship program at the University of California at Davis. Dr. Chang has previously been Chief of the Division of Allergy and Immunology at Thomas Jefferson University and Nemours Children's Hospital in Philadelphia, PA and Wilmington, DE, respectively. He is a fellow of the American Academy of Allergy, Asthma and Immunology (AAAAI) and the American College of Allergy, Asthma and Immunology (ACAAI), and a member of the Clinical Immunology Society (CIS) and the American Association of Immunologists (AAI). He is Chair of the Core Curriculum, Education and Residency Review Committee of the AAAAI and Vice-chair of the Training Program Directors Committee of the ACAAI. He has over 100 original publications and has authored over 20 chapters in immunology, rheumatology and allergy books, and has also edited 2 books with a third on the way. He has over 30 years' experience in the practice of Immunology and Allergy and has been involved in the education of future allergists and immunologists at the levels of the medical student, resident and fellow.