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Integrated Physiology and Pathophysiology

  • Book

  • December 2021
  • Elsevier Health Science
  • ID: 5275383
Edited by physiology instructors who are also active clinicians, Integrated Physiology and Pathophysiology is a one-stop guide to key information you need for early clinical and medical training and practice. This unique, integrated textbook unites these two essential disciplines and focuses on the most relevant aspects for clinical application. A concise, review-like format, tables and diagrams, spaced repetition for effective learning, and self-assessment features help you gain and retain a firm understanding of basic physiology and pathophysiology. Integrated Physiology and Pathophysiology works equally well as a great starting point in your studies and as a review for boards.

- Shares the knowledge and expertise of an outstanding editorial team consisting of two practicing clinicians who also teach physiology and pathophysiology at Harvard Medical School, plus a top Harvard medical student.

- Provides an integrated approach to physiology and pathophysiology in a concise, bulleted format. Chapters are short and focus on clinically relevant, foundational concepts in clear, simple language.

- Employs focused repetition of key points, helping you quickly recall core concepts such as pressure-flow-resistance relationships, ion gradients and action potentials, and mass balance. You'll revisit these concepts in a variety of meaningful clinical contexts in different chapters; this "spaced learning" method of reinforcement promotes deeper and more flexible understanding and application.

- Includes Fast Facts boxes that emphasize take-home messages or definitions.

- Contains Integration boxes that link physiology and pathophysiology to pharmacology, genetics, and other related sciences.

- Presents clinical cases and with signs and symptoms, history, and laboratory data that bring pathophysiology to life.

- Features end-of-chapter board-type questions, complete with clear explanations of the answers, to help prepare you for standardized exams. - Enhanced eBook version included with purchase. Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.

Table of Contents

Section 1: Foundations 1. General Principles of Physiology 1.1 Case Study #1 Section 2: Neurophysiology 2. An Overview of Nerve Cell Physiology and Electrophysiology 3. Central Nervous System 4. Peripheral Nervous System and the Autonomic Nervous System 5. The Neuromuscular Junction and Skeletal Muscle 6. Smooth Muscle 6.1 Case Study #2 Section 3: Circulatory Physiology 7. Blood and the Endothelium 8. The Lymphatic System and the Immune System 8.1 Case Study #3 Section 4: Cardiovascular Physiology 9. The Vasculature 10. The Heart As a Pump 11. Cardiac Electrophysiology 12. Exercise Physiology 12.1 Case Study #4 Section 5: Pulmonary Physiology 13. The Mechanics of Breathing 14. Gas Exchange in the Lung 15. Gas Transport 16. The Regulation of Breathing 16.1 Case Study #5 Section 6: Renal Physiology 17. Renal Structure and Function 18. Tubular Transport 19. The Regulation of Blood Pressure and Extracellular Fluid Volume 20. Osmoregulation 21. The Regulation of Potassium Balance 22. Acid-Base Balance 23. Micturition 23.1 Case Study #6 Section 7: Gastrointestinal Physiology 24. Nutrition, Digestion, and Absorption 25. Control of Gastrointestinal Motility and Secretion 26. Hepatic Physiology 27. The Gastrointestinal Immune System 27.1 Case Study #7 Section 8: Endocrine Physiology 28. The Endocrine Pancreas: Fed and Fasted Metabolic States 29. The Pituitary Gland 30. The Thyroid Gland 31. The Adrenal Gland 32. Calcium Regulation: Parathyroid Physiology 33. Calcium Regulation: Bone Physiology 34. The Female Reproductive System 35. Pregnancy and Partiution 36. The Male Reproductive System

Authors

Julian L Seifter Director, Renal Medical Student Education; Associate Professor, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts. Elisa Walsh David E Sloane Instructor in Medicine, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.