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Traumatic Brain Injury - Epidemiology Forecast - 2034

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    Report

  • 60 Pages
  • December 2024
  • Region: Global
  • DelveInsight
  • ID: 5292776
UP TO OFF until Dec 31st 2024

Key Highlights

  • The analyst projects that the total number of Traumatic Brain Injury cases in 7MM were approximately 4.19 million in 2022 and these cases are further expected to increase during the forecasted period (2023-2034).
  • According to analysis, the total number of incident cases in the US was found to be 2.96 million in 2022 and is estimated to increase with a significant CAGR throughout the forecast period.
  • In 2022, the total number of incident cases of TBI was 906 thousand in EU4 and the UK, which is anticipated to increase during the study period [2020-2034].
  • According to estimates, Japan accounted for 8% of the total Incident Cases of TBI in the 7MM in 2022.
The “Traumatic Brain Injury (TBI)- Epidemiology - 2034” report delivers an in-depth understanding of Traumatic Brain Injury, historical and forecasted epidemiology of Traumatic Brain Injury in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

Geography Covered

  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan

Study Period: 2020-2034

Traumatic Brain Injury Disease Understanding

Traumatic Brain Injury Overview

Traumatic Brain Injury (TBI) is sudden damage to the brain caused by a blow or jolt to the head. Common causes include car or motorcycle crashes, falls, sports injuries, and assaults. Injuries can range from mild concussions to severe permanent brain damage. The injury that occurs at the moment of impact is known as the primary injury. Primary injuries can involve a specific lobe of the brain or can involve the entire brain. Sometimes, the skull may be fractured, but not always. During the impact of an accident, the brain crashes back and forth inside the skull, causing bruising, bleeding, and tearing of nerve fibers.

Symptoms of a TBI can be mild, moderate, or severe, depending on the extent of the damage to the brain. A person with a mild TBI may remain conscious or experience a loss of consciousness for a few seconds or minutes. Other symptoms of mild TBI include headache, confusion, lightheadedness, dizziness, blurred vision or tired eyes, ringing in the ears, bad taste in the mouth, fatigue or lethargy, a change in sleep patterns, behavioral or mood changes, and trouble with memory, concentration, attention, or thinking. A person with a moderate or severe TBI may show these same symptoms but may also have a headache that gets worse or does not go away, repeated vomiting or nausea, convulsions or seizures, an inability to awaken from sleep, dilation of one or both pupils of the eyes, slurred speech, weakness or numbness in the extremities, loss of coordination, and increased confusion, restlessness, or agitation.

Traumatic Brain Injury Diagnosis

No single test is able to confirm the diagnosis of TBI definitively. Doctors assess the history of the injury, the patient’s symptoms, the physical examination, and additional tests, including neuroradiology, to confirm a diagnosis of TBI. Many TBI patients experience a loss of consciousness (blacking out) at the time of their injury. Loss of consciousness most commonly lasts from seconds to minutes, but severe TBI may last for days (coma) and may persist indefinitely in the most severe cases. Patients with mild TBI (concussion) may not experience any loss of consciousness. Most TBI patients have some degree of amnesia (loss of memory) for the minutes to hours or longer surrounding their injury.

Traumatic Brain Injury Epidemiology

As the market is derived using the patient-based model, the Traumatic Brain Injury epidemiology chapter in the report provides historical as well as forecasted epidemiology segmented by Total Incident Cases of TBI, Severity-specific Incident Cases of TBI, Gender-specific Incident Cases of TBI, and Age-specific Incident Cases of TBI in the 7MM covering the United States, EU4 countries (Germany, France, Italy, and Spain) and the United Kingdom, and Japan, from 2020 to 2034.

According to estimations, 4.19 million Incident Cases of Traumatic Brain Injury were found in 2022 in the 7MM.

As per estimations, the total number of cases with Traumatic Brain Injury in the United States were 2.96 million in 2022 and are projected to increase during the forecast period.

According to estimates, the Total Incident Cases of Traumatic Brain Injury in EU4 and the UK were found to be 906 thousand in 2022. The highest proportion of Traumatic Brain Injury cases was reported in Germany among the EU4 countries, while the least number of cases was found in Spain.

The estimates show the number of Traumatic Brain Injury cases in Japan was found to be 326 thousand in 2022, which is estimated to decrease by 2034.

The gender-specific incident cases of TBI in the 7MM were 1.42 million for females and 2.76 million for males in 2022 and are expected to increase within the forecast period (2023-2034).

As per the analysis, the incident cases of TBI based on age were categorized into children and adults. The higher number of cases (2,982 thousand) was accounted for by adults in 2022 in the 7MM.

The severity-specific cases of TBI were categorized as mild, moderate, and severe. As per estimations, analysts show that the overall severity-specific cases of TBI are subjected to an increase by 2034 from 3.41 million, 400 thousand, and 382 thousand cases, respectively, in 2022.

KOL Views

To gaze into the epidemiology insights of the real world, we take KOLs and SMEs’ opinions working in the domain through primary research to fill the data gaps and validate our secondary research on disease prevalence.

The analysts connected with 20+ KOLs to gather insights; however, interviews were conducted with 10+ KOLs in the 7MM. Centers such as the University of Maryland School of Medicine, USA, Department of Neurological Surgery, University of Miami Miller School of Medicine, USA, National Academies of Sciences, Engineering, and Medicine, USA, BG University Hospital Bergmannsheil, Germany, Institut Guttmann Neurorehabilitation Hospital, Spain, Keio University School of Medicine, Japan and others were contacted. Their opinion helps understand and validate current disease prevalence, gender involved with the disease, diagnosis rate, and diagnostic criteria.

Scope of the Report

  • The report covers a segment of key events, an executive summary, descriptive overview of Traumatic Brain Injury, explaining its causes, signs and symptoms, and currently available therapies.
  • Comprehensive insight has been provided into the epidemiology segments and forecasts, the future growth potential of diagnosis rate, disease progression, and treatment guidelines.
  • The report provides an edge for understanding trends, expert insights/KOL views, and patient journeys in the 7MM.
  • A detailed review of current challenges in establishing the diagnosis.

Traumatic Brain Injury Report Insights

  • Patient Population
  • Country-wise Epidemiology Distribution
  • Incident Cases of TBI
  • Severity-specific Incident Cases of TBI
  • Gender-specific Incident Cases of TBI
  • Age-specific Incident Cases of TBI

Traumatic Brain Injury Report Key Strengths

  • 12 years Forecast
  • The 7MM Coverage
  • Traumatic Brain Injury Epidemiology Segmentation

Traumatic Brain Injury Report Assessment

  • Current Diagnostic Practices Patient Segmentation

Epidemiology Insights

  • What are the disease risk, burdens, and unmet needs of Traumatic Brain Injury? What will be the growth opportunities across the 7MM concerning the patient population of Traumatic Brain Injury?
  • What is the historical and forecasted Traumatic Brain Injury patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?
  • Why is the incident cases of TBI in Japan lower than the US?
  • Which country has a high patient share for TBI?

Reasons to Buy

  • Insights on patient burden/disease, evolution in diagnosis, and factors contributing to the change in the epidemiology of the disease during the forecast years.
  • To understand the Traumatic Brain Injury prevalence cases in varying geographies over the coming years.
  • A detailed overview of Severity, Gender, and Age-specific incidence of TBI.
  • To understand the perspective of key opinion leaders around the current challenges with establishing the diagnosis options.
  • Detailed insights on various factors hampering disease diagnosis and other existing diagnostic challenges.

Frequently Asked Questions

1. What is the forecast period covered in the report?

The Traumatic Brain Injury Epidemiology report for the 7MM covers the forecast period from 2023 to 2034, providing a projection of epidemiology dynamics and trends during this timeframe.

2. Out of all EU4 countries and the UK, which country had the highest population of Traumatic Brain Injury (TBI) cases in 2022?

The highest cases of Traumatic Brain Injury was found in the Germany among EU4 and the UK in 2022.

3. How is epidemiological data collected and analyzed for forecasting purposes?

Epidemiological data is collected through surveys, clinical studies, health records, and other sources. It is then analyzed to calculate disease rates, identify trends, and project future disease burdens using mathematical models.

4. Out of all 7MM countries, which country had the highest population of Traumatic Brain Injury (TBI) cases in 2022?

The highest cases of Traumatic Brain Injury were found in the US among the 7MM in 2022.

Table of Contents

1. Key Insights2. Report Introduction
3. Traumatic Brain Injury (TBI) Epidemiology Overview
3.1. Patient Share (%) Distribution of TBI in 2020
3.2. Patient Share (%) Distribution of TBI in 2034
4. Epidemiology Methodology of TBI5. Executive Summary of TBI6. Key Events
7. Disease Background and Overview
7.1. Introduction
7.2. Symptoms
7.3. Etiology
7.4. Pathophysiology
7.5. Neurodegenerative Conditions Associated With TBI
7.6. Biomarkers
7.7. Diagnosis
7.7.1. Diagnostic Algorithm
7.7.2. Diagnostic Guidelines
7.7.2.1. The American Congress of Rehabilitation Medicine Diagnostic Criteria for Mild TBI
7.7.2.2. Guidelines for Adult Patients with Mild TBI (A part of CDC’s “Heads Up” Series)
7.7.2.3. Centers for Disease Control and Prevention Guideline on the Diagnosis and Management of Mild TBI among Children
8. Epidemiology and Patient Population
8.1. Key Findings
8.2. Assumptions and Rationale: The 7MM
8.2.1. Incidence of TBI
8.2.2. Severity-specific Incidence of TBI
8.2.3. Gender-specific Incidence of TBI
8.2.4. Age-specific Incidence of TBI
8.3. Total Incident Cases of TBI in the 7MM
8.4. The United States
8.4.1. Total Incident Cases of TBI in the US
8.4.2. Severity-specific Incident Cases of TBI in the US
8.4.3. Gender-specific Incident Cases of TBI in the US
8.4.4. Age-specific Incident Cases of TBI in the US
8.5. EU4 and the UK
8.5.1. Total Incident Cases of TBI in EU4 and the UK
8.5.2. Severity-specific Incident Cases of TBI in EU4 and the UK
8.5.3. Gender-specific Incident Cases of TBI in EU4 and the UK
8.5.4. Age-specific Incident Cases of TBI in EU4 and the UK
8.6. Japan
8.6.1. Total Incident Cases of TBI in Japan
8.6.2. Severity-specific Incident Cases of TBI in Japan
8.6.3. Gender-specific Incident Cases of TBI in Japan
8.6.4. Age-specific Incident Cases of TBI in Japan
9. Patient Journey10. Key Opinion Leaders’ Views
11. Appendix
11.1. Bibliography
11.2. Acronyms and Abbreviations
12. Report Methodology13. Publisher Capabilities14. Disclaimer
List of Tables
Table 1: Summary of TBI Epidemiology (2020-2034)
Table 2: Key Events
Table 3: Classification of TBI
Table 4: Indication for Immediate CT Scan
Table 5: Criteria for Inclusion and Exclusion
Table 6: Total Incident Cases of TBI in the 7MM, in ‘000’ (2020-2034)
Table 7: Total Incident Cases of TBI in the US, in ‘000’ (2020-2034)
Table 8: Severity-specific Incident Cases of TBI in the US, in ‘000’ (2020-2034)
Table 9: Gender-specific Incident Cases of TBI in the US, in ’000’ (2020-2034)
Table 10: Age-specific Incident Cases of TBI in the US, ‘000’ (2020-2034)
Table 11: Total Incident Cases of TBI in EU4 and the UK, ‘000’ (2020-2034)
Table 12: Severity-specific Incident Cases of TBI in Germany, ‘000’ (2020-2034)
Table 13: Severity-specific Incident Cases of TBI in France, ‘000’ (2020-2034)
Table 14: Severity-specific Incident Cases of TBI in Italy, in ‘000’ (2020-2034)
Table 15: Severity-specific Incident Cases of TBI in Spain,’000’ (2020-2034)
Table 16: Severity-specific Incident Cases of TBI in the UK, ‘000’ (2020-2034)
Table 17: Severity-specific Incident Cases of TBI in EU4 and the UK, ‘000’ (2020-2034)
Table 18: Gender-specific Incident Cases of TBI in Germany, in ‘000’ (2020-2034)
Table 19: Gender-specific Incident Cases of TBI in France, in ’000’ (2020-2034)
Table 20: Gender-specific Incident Cases of TBI in Italy, in ‘000’ (2020-2034)
Table 21: Gender-specific Incident Cases of TBI in Spain, in ‘000’ (2020-2034)
Table 22: Gender-specific Incident Cases of TBI in the UK, in ‘000’ (2020-2034)
Table 23: Gender-specific Incident Cases of TBI in EU4 and the UK, in ‘000’ (2020-2034)
Table 24: Age-specific Incident Cases of TBI in Germany, in ‘000’ (2020-2034)
Table 25: Age-specific Incident Cases of TBI in France, in ‘000’ (2020-2034)
Table 26: Age-specific Incident Cases of TBI in Italy, in ‘000’ (2020-2034)
Table 27: Age-specific Incident Cases of TBI in Spain, in ‘000’ (2020-2034)
Table 28: Age-specific Incident Cases of TBI in the UK, in ‘000’ (2020-2034)
Table 29: Age-specific Incident Cases of TBI in EU4 and the UK, in ‘000’ (2020-2034)
Table 30: Total Incident Cases of TBI in Japan, in ‘000’ (2020-2034)
Table 31: Severity-specific Incident Cases of TBI in Japan, in ‘000’ (2020-2034)
Table 32: Gender-specific Incident Cases of TBI in Japan, in ‘000’ (2020-2034)
Table 33: Age-specific Incident Cases of TBI in Japan, in ‘000’ (2020-2034)
List of Figures
Figure 1: Traumatic Brain Injury
Figure 2: Symptoms of TBI
Figure 3: Pathophysiology of TBI
Figure 4: Different Phases of TBI Pathophysiology and Relative Immune Response
Figure 5: Schematic Representation of Pathophysiology of TBI
Figure 6: Diagnostic Criteria for Mild TBI
Figure 7: Total Incident Cases of TBI in the 7MM (2020-2034)
Figure 8: Total Incident Cases of TBI in the US (2020-2034)
Figure 9: Severity-specific Incident Cases of TBI in the US (2020-2034)
Figure 10: Gender-specific Incident Cases of TBI in the US (2020-2034)
Figure 11: Age-specific Incident Cases of TBI in the US (2020-2034)
Figure 12: Total Incident Cases of TBI in EU4 and the UK (2020-2034)
Figure 13: Severity-specific Incident Cases of TBI in EU4 and the UK (2020-2034)
Figure 14: Gender-specific Incident Cases of TBI in EU4 and the UK (2020-2034)
Figure 15: Age-specific Incident Cases of TBI in EU4 and the UK (2020-2034)
Figure 16: Total Incident Cases of TBI in Japan (2020-2034)
Figure 17: Severity-specific Incident Cases of TBI in Japan (2020-2034)
Figure 18: Gender-specific Incident Cases of TBI in Japan (2020-2034)
Figure 19: Age-specific Incident Cases of TBI in Japan (2020-2034)
Figure 20: Patient Journey of TBI