The Global Exosome Market: Size, Forecast, Trials, and Trends, 2024

1.1 Statement of the Report
1.2 Target Demographic
1.3 Report Sources
1.4 Purpose of the Report
1.5 Executive Summary
1.6 Introduction

2.1 Structure of an Exosome
2.1.1 Molecular Contents of Exosomes
2.1.1.1 Proteins in Exosomes
2.1.1.2 Lipid Contents of Exosomes
2.1.1.3 Nucleic Acids in Exosomes
2.1.2 Membrane and Lumen Components of Exosomes
2.1.3 Classification of Exosomes by Origin
2.1.3.1 Natural Exosomes
2.1.3.1.1 Isolation of Natural Exosomes
2.1.3.2 Modified Exosomes
2.1.3.2.1 Types of Therapeutic Cargos Loaded into Exosomes
2.1.3.2.2 Biomedical Applications of Engineered Exosomes
2.1.4 Synthetic Exosomes
2.2 Differences between Cell Therapy and Gene Therapy
2.3 The Shift from Cell Therapy to Exosome Therapy
2.4 Exosomes in the Next Ten Years

3.1 Interior Modification
3.1.1 Pre-Isolation Interior Modification Methods
3.1.2 Incubation
3.1.3 Gene Editing
3.1.4 Post-Isolation Interior Modification Methods
3.2 Surface Modifications
3.2.1 Surface Modification through Parent Cell
3.2.2 Direct Surface Modification
3.2.3 Displayed Molecules in Exosomes
3.3 Interior Modification
3.3.1 Pre-Isolation Interior Modification
3.3.2 Post-Isolation Modification Methods
3.4 An Exosome Showing Modified Surface and Modified Interior
3.4.1 Examples of Hydrophilic Cargo Loaded into Exosome Lumen

4.1 Publication Trends of Exosome Diagnostics and Therapeutics
4.2 PubMed Publications on Therapeutic Exosomes by Loading Technology
4.3 PubMed Papers on Exosome Isolation & Purification by Technology
4.4 PubMed Papers on Lipid Nanoparticles and Exosomes as Drug Carriers
FIGURE 4.5: PubMed Papers on Lipid Nanoparticles and Exosomes as Drug Carriers
4.5 Distribution of Exosome Publications by Disease Type
4.6 Exosome Publications by Cancer Type

5.1 Exosome Patent Publications over Time
5.2 Exosome Patents: Therapeutic vs. Diagnostics
5.3 Exosome Patent Applications by Exosome Source
5.4 Patents/Patent Applications by Isolation/Purification Technologies
5.5 Patents/Patent Applications by Type of Cargo
5.6 Patents/Patent Applications by Cargo Loading Methods
5.7 Patents/Patent Applications by Therapy Area
5.8 Leading Assignees of Exosome Patents
5.8.1 Types of Patented Isolation/Preparations Technologies by Assignees
5.8.2 Types of Cargos Employed by Assignees
5.8.3 Cargo Loading Methods by Assignees
5.8.4 Therapy Areas by Assignees
5.8.5 Assignee Categories
5.9 Exosome Patent Applications by Jurisdiction
5.10 Exosome Patent Applicants
5.11 Exosome Patent Inventors
5.12 Exosome Patent Owners
5.13 Legal Status of Exosome Patents

6.1 Exosome Clinical Trials by Phase of Study
6.2 Exosome Clinical Trials by Funder Type
6.3 Exosome Clinical Trials by Technology
6.4 Current Status of Clinical Trials using Exosomes in Treating Diseases
6.5 Clinical Trials using Exosomes for Diagnostic Studies
6.6 Major Exosome R&D Companies
6.7 Exosome Therapeutics in Preclinical Development

7.1 Ultracentrifugation (UC)
7.1.1 Differential Ultracentrifugation
7.1.2 Density Gradient Ultracentrifugation (DGU)
7.2 Ultrafiltration (UF)
7.2.1 Tandem-Configured Ultrafiltration
7.2.2 Sequential Ultrafiltration
7.3 Size Exclusion Chromatography (SEC)
7.4 Polymer Precipitation Method
7.5 Immunoaffinity Capture Method
7.6 Aptamer-Based Method
7.7 Microfluidic Technique

8.1 Description of Select Exosome Technology Platforms
8.1.1 AGLE-102
8.1.2 Hybridosome
8.1.3 AB126
8.1.4 CAP-1002 (Deramiocel)
8.1.5 REGENT
8.1.6 ExoFlo
8.1.7 DeliverEX
8.1.8 EXOVEX
8.1.9 ExoSCRT
8.1.10 LEAP
8.1.11 ExoDx
8.1.12 EXPLOR
8.1.13 Exo-Target

9.1 Incubation Method
9.2 Transfection Method
9.3 Sonication Method
9.4 Electroporation Method
9.5 Extrusion Method
9.6 Freeze/Thaw Method
9.7 Genetic Engineering Method

10.1 Key Players in the Exosome Therapeutic Space
10.1.1 EXO-CD24 from Nano24 (OBCTCD24)
10.1.2 The Hemopurifier
10.1.2.1 Hemopurifier in Cancer
10.1.2.2 Hemopurifier in Infectious Diseases
10.1.3 REGENT from Carmine Therapeutics
10.1.4 Exosome Customization Technology from Ciola
10.1.5 CAP-1002 (Deramioce) from Capricor Therapeutics
10.1.6 EXPLOR from ILIAS Biologics
10.1.7 AB126 from Aruna Bio
10.1.8 AGLE-102 from Aegle Therapeutics
10.1.9 OmniSomes from OmniSpirant Therapeutics
10.1.10 EXO-101 from Exogenus Therapeutics
10.1.11 Purified Exosome Product (PEP) from RION

11.1 Advantages in Diagnostic Applications
11.2 Major Indications Focused for Diagnosis
11.3 Most Common Targeted Exosome Biomarkers
11.3.1 Exosomal Proteins for Diagnostic Applications
11.3.2 Exosomal miRNAs as Cancer Diagnostic Agents
11.4 Diagnostic Exosome Research
11.5 Key Players in the Development of Exosome Diagnostics
11.5.1 LiquidScan from BioFluidica
11.5.2 ExoEnrich from ExoCan
11.5.3 ExoDx Prostate Test from Exosome Diagnostics, Inc.
11.5.4 TauSome Test from Exosome Sciences
11.5.5 Cancer Diagnosis from Exosomics S.p.A
11.5.6 Guardant360 CDx from Guardant Health
11.5.7 Liver Cancer Detection study by Mursla Bio
11.5.8 BDE Biomarker Assay from NanoSomiX
11.5.9 ExoScreen Assay from Theoria Science

12.1 Aesthetic Exosome Treatments
12.1.1 Exosomes in Facial Rejuvenation
12.1.2 Exosomes in Hair Restoration
12.1.3 Exosomes in Scar Reduction
12.1.4 Exosomes in Breast Augmentation
12.2 Sources of Exosomes for Aesthetic Use
12.3 Science behind Dermatologically Relevant Exosomes
12.4 Key Players & Products
12.5 Popular Exosome-Based Aesthetics
12.5.1 AnteAGE Pro System
12.5.2 ExoCR from Cartessa
12.5.3 ELEVAI enfinity from ELEVAI Labs
12.5.4 EXO PLUS from Exoceuticals
12.5.5 Vive from Kimera Labs
12.5.6 CALM Serum from RION Aesthetics
12.5.7 ASCE Exosomes from ExoCoBio

13.1 Venture Capital Funding for Exosome companies
13.1.1 EXO Biologics
13.1.2 Exogenus Therapeutics
13.1.3 INEXOPLAT
13.1.4 Mantra Bio
13.1.5 Anjarium Biosciences
13.1.6 Evox Therapeutics, Ltd.
13.1.7 ILIAS Biologics
13.1.8 ExoCoBio, Inc.
13.1.9 Aegle Therapeutics
13.1.10 Evox Therapeutics
13.1.11 Evox Therapeutics
13.1.12 Codiak BioSciences
13.1.13 Codiak BioSciences
13.1.14 Exosome Diagnostics
13.1.15 Exosome Diagnostics, Inc
13.2 Partnership Deals in Exosome Space
13.2.1 Cytiva & Rooster Bio
13.2.2 SomesTech & ConvEyXO
13.2.3 RoosterBio, Inc. & FUJIFILM Diosynth Biotechnologies
13.2.4 Evox Therapeutics & Eli Lilly
13.2.5 Exopharm & Astellas
13.2.6 Univercells Technologies & RoosterBio
13.2.7 AgeX Therapeutics & UCI
13.2.8 VivaZome & La Trobe University
13.2.9 Evotec SE & Curexsys GmbH
13.2.10 Bio-Techne & QIAGEN
13.2.11 InnoCan Pharma & Recipharms
13.2.12 Codiak BioSciences & Sarepta
13.2.13 Evox Therapeutics & Takeda
13.2.14 PureTech & Roche
13.2.15 Evox Therapeutics & Boehringer Ingelheim
13.2.16 Sarpeta Therapeutics & Codiak Biosciences
13.2.17 Navigo Proteins & MDimune
13.2.18 Jazz Pharmaceuticals & Codiak BioSciences
13.2.19 Exosome Diagnostics & Intezyne
13.2.20 Evox Therapeutics & Boehringer Ingelheim
13.3 Acquisition Deals
13.3.1 ExoCoBio & BENEV
13.3.2 Evox Therapeutics & Codiak Biosciences’ Technology
13.3.3 Lonza & Exosomics
13.3.4 Lonza & Codiak Biosciences
13.3.5 Bio-Techne Corporation & Exosome Diagnostics
13.3.6 Lonza & HansaBioMed
13.4 Licensing Deals
13.4.1 EVerZom & Erganeo
13.4.2 Elevai Labs & Yuva Biosciences
13.4.3 TOPPAN & Dai Nippon Toryo
13.4.4 Carnegie Mellon University (CMU) & Coya Therapeutics
13.4.5 INOVIQ, Ltd. & ResearchDx, Inc.
13.4.6 ATUM & Codiak BioSciences
13.4.7 Johns Hopkins University & Capricor Therapeutics
13.4.8 Evox Therapeutics & Eli Lily
13.4.9 Codiak BioSciences & Sarepta
13.4.10 VivaZome Therapeutics & University of Adelaide
13.4.11 Evox Therapeutics & Takeda
13.4.12 CEVEC & Evox Therapeutics
13.4.13 Orgenesis & Excella Bio
13.4.14 System Biosciences & QIAGEN
13.4.15 PureTech Health & 3D Biotechnologies
13.5 IPO
13.5.1 Elevai Labs
13.5.2 Codiak Biosciences
13.5.3 Codiak Biosciences
13.5.4 Codiak BioSciences

14.1 Market for Exosome Therapeutics
14.2 The Global Market for Ready-to-Use Purified Exosomes by Type
14.2.1 Market Size of Exosomes by Parent Cell Type
14.3 Market for Exosome Diagnostics
14.4 Global Exosome Technologies Market by Product Type
14.5 Global Exosome-Based Aesthetics (Cosmeceuticals) Market
14.6 The Overall Market for Exosomes
14.7 The Market Driver of Exosome Therapies

15.1 101 Bio
15.1.1 PureExo Exosome Isolation Kit
15.2 Abbexa, Ltd.
15.3 AcouSort AB
15.3.1 Technology: Acoustic Separation
15.3.2 EIC Award
15.4 Aegle Therapeutics
15.4.1 Research & Development
15.5 Aethlon Medical, Inc.
15.5.1 Hemopurifier
15.6 Akrivis Health Care Pvt., Ltd.
15.7 AM BioTech
15.7.1 Bio-Pulsed Technology
15.7.2 ExoGiov
15.7.3 LA EXO Exosome Cosmetics
15.8 AMS Biotechnology, Ltd. (AMSBIO)
15.9 AnteAGE
15.9.1 At-Home Skincare Products
15.9.2 At-Home Brow & Lash Products
15.9.3 VRS Box (6 Pack) [$150]
15.9.4 Professional Skincare Products
15.9.5 Growth Factor Microneedling Products
15.9.6 Stem Cell Facial Microchanneling Products
15.9.7 Medical Skin Care Products
15.9.8 Growth Factor Skin Treatment Products
15.9.9 Growth Factor Hair Regeneration Products
15.10 Aposcience AG
15.10.1 Wound Healing
15.10.2 Myocardial Infarction
15.11 Aruna Bio
15.11.1 AB126 (Neural Exosome)
15.12 BENEV Company, Inc. (ExoCoBio)
15.12.1 Exosome Regenerative Complex
15.12.2 Exosome Regenerative Complex +
15.12.3 EXO-XOM Facial
15.13 BioCat GmbH
15.13.1 ExoQuick Exosome Precipitation
15.13.2 Exosome RNA & DNA Purification
15.13.3 Exosome RNA Amplification & Profiling
15.13.4 Exosome Quantification
15.13.5 Exosome Antibody Array
15.13.6 ExoGlow EV Labeling Kits
15.13.7 Exosome Engineering
15.14 BioFluidica
15.14.1 LiquidScan
15.14.2 Exosome Isolation
15.15 Biological Dynamics, Inc.
15.15.1 Verita Technology
15.15.2 ExoVerita Pro Exosome Enrichment Platform
15.15.3 Exosome Isolation & Analysis Services
15.16 Biorbyt, Ltd.
15.17 Bioscience Institute
15.17.1 Bioscience Clinic Middle East
15.17.2 Bioscience Genomics
15.17.3 Services
15.17.3.1 ExoSkin Therapy
15.17.3.2 ExoHair Therapy
15.17.3.3 ExoJoints Therapy
15.17.3.4 ExoMale Therapy
15.17.3.5 ExoFemale Therapy
15.17.3.6 XOLINE Exosome Cosmetics
15.18 Biosynth International, Inc.
15.18.1 ME Kit (Microvesicle Extraction Kit)
15.19 BreStem Therapeutics, Inc.
15.20 Capricor Therapeutics
15.20.1 Portfolio
15.20.2 StealthX Technology
15.21 Carmine Therapeutics
15.21.1 REGENT Platform
15.22 Cellarcus Biosciences, Inc.
15.22.1 vFC Vesicle Analysis Assays
15.22.2 vTAG Antibodies
15.22.3 Vesicles and Vesicle Assay Standards
15.23 Cell Care Therapeutics
15.23.1 CCT-101
15.24 Cells for Cells
15.24.1 Current Clinical Trial using Exosomes
15.25 Cell Guidance Systems, Ltd.
15.25.1 Exosome Products
15.25.2 Exo-spin Purification
15.25.3 ExoLISA Technology: Exosome Detection
15.25.4 Exosome Validated Antibodies
15.25.5 Instant Exosomes
15.25.6 NTA Size Profiling Service
15.26 Ciloa
15.26.1 Antibodies against Undruggable Targets
15.26.2 Adjuvant & Virus-Free Vaccines
15.26.3 Virus-Free Therapeutic Vectors
15.26.4 Technology
15.27 ConvEyXO
15.27.1 Exo-Harvest Technology
15.27.2 XomeXBio Technology
15.28 Craif, Inc.
15.28.1 NANO IP (Nano Intelligence Platform)
15.29 Creative Bioarray
15.29.1 Exosome Antibodies
15.29.2 Exosome DNA-RNA Extraction Kits
15.29.3 Exosome Isolation Tools
15.29.4 Exosome Standards
15.29.5 Fluorescent Exosome Standards
15.29.6 Liquid Biopsy
15.29.7 Exosome Research Services
15.30 Creative Biostructure
15.30.1 Exosome Products
15.30.2 Exosome Services
15.30.2.1 Exosome Isolation Services
15.30.2.2 Exosome Analysis Services
15.30.2.3 Exosome Characterization Services
15.30.2.4 Exosome Engineering Services
15.30.2.5 Exosome In Vitro Functional Assay
15.30.2.6 Exosome In Vitro Functional Assay
15.31 Creative Biolabs
15.31.1 Exosome Products
15.31.2 Exosome Isolation Tools
15.31.3 Exosome Capture & Quantification Kits
15.31.4 Exosome Antibody Products
15.31.5 Exosome Standards
15.31.6 Exosome Labeling Kits
15.31.7 Exosomes Surface Modification Kits
15.31.8 Exosome Identification Kits
15.31.9 Exosome Marker cDNA Plasmid Products
15.31.10 Exosome Release Modulation Reagents
15.31.11 LipidSync Exosomes
15.31.12 Exosome Services
15.32 Creative Medical Technology Holdings, Inc.
15.32.1 AmnioStem Stroke Therapy
15.33 Creative Proteomics
15.33.1 Exosome Services
15.34 CUSABIO Technology LLC
15.34.1 Exosome Isolation Kits
15.35 Diadem Biotherapeutics
15.35.1 Technology
15.36 Direct Biologics
15.36.1 ExoFlo
15.36.2 AmnioWrap
15.37 Elevai Labs, Inc.
15.37.1 ELEVAI enfinity
15.37.2 ELEVAI empower
15.37.3 ELEVAI Root Renewal System
15.38 Entelexo Biotherapeutics
15.39 EriVan Bio
15.39.1 Services
15.39.2 Research Products
15.40 EVerZom
15.40.1 EVerZom Platform
15.41 Evolutionary Biologics, Inc.
15.41.1 EXO ELIXIR
15.41.2 EVO GROW
15.41.3 EVO JEL
15.41.4 EXO RNA
15.41.5 EVO HYBRID
15.41.6 EXO PERIO
15.42 Evomic Science LLC
15.42.1 ExoEZ Exosome Isolation Kit
15.43 Evox Therapeutics, Ltd.
15.43.1 Gene Therapy
15.43.2 Gene Editing
15.43.3 RNA Therapeutics
15.43.4 Precision Therapeutic Targeting
15.43.5 Protein Therapeutics
15.43.6 Manufacturing Exosomes
15.43.7 Focus on Rare Diseases
15.44 EXO Biologics
15.44.1 Lead Product Candidate
15.45 ExoCan Healthcare Technologies Pvt., Ltd.
15.45.1 ExoEnrich
15.45.2 ExoEngineering
15.45.3 SAC-3D
15.45.4 Services
15.45.4.1 Multiphenotype Screen
15.45.4.2 Small Molecule Screening
15.45.4.3 Exo-BiDD
15.46 Exocel Bio
15.46.1 Services
15.46.1.1 Exosome Isolation via Ultracentrifugation
15.46.1.2 Nanoparticle Analysis for Size Distribution and Concentration
15.46.1.3 Custom Experiments with NTA
15.46.1.4 Custom Growth Factors Production
15.46.2 Products
15.46.2.1 Exovex REVIVE
15.46.2.2 Exovex RENEW
15.46.2.3 Exovex REVEAL
15.46.2.4 Exovex REFINE
15.46.2.5 Exovex RESTORE
15.46.2.6 Exovex EQUUSOME
15.46.2.7 Exovex CANISOME
15.46.2.8 Exovex FELISOM
15.47 Exogenus Therapeutics
15.47.1 Exo-101
15.47.2 ExoWound
15.48 Exokeryx, Inc.
15.48.1 Demeter EVPrep
15.48.2 ExoScan
15.49 ExoProTher Medical
15.50 ExoQure
15.50.1 Technology
15.50.2 Products
15.51 EXORPHIA, Inc.
15.51.1 Activation Technology to produce Prime-EV
15.51.2 Modification Technology to Produce Smart-EV
15.51.3 INPACT-EV Technology
15.51.4 EV Analysis Technology: EV-QUEST
15.51.5 EXORPHIA’s Product Pipeline
15.52 ExosomeDx (biotechne)
15.52.1 ExoDx Prostate Test
15.52.2 Pharma Services
15.52.3 Biomarker Discovery Services
15.53 ExosomePlus
15.53.1 MSC-Derived Exosomes
15.53.2 ExoCope Technology
15.54 Exosome Sciences
15.54.1 TauSome (Exosomal Tau) Biomarker
15.55 ExoStemTech Co., Ltd.
15.55.1 Cartisome
15.55.2 EST-T-EXO
15.55.3 Hepatosome
15.55.4 Hypoxisome
15.55.5 Exosome Manufacturing Platform
15.55.6 Protein Loading & Delivery Platform
15.56 ExoVectory
15.56.1 Technology
15.56.2 Therapeutic Areas Focused
15.56.3 Exosome Immunotherapy for Cancer
15.56.4 Exosome Gene Therapy
15.57 ExSURE Pvt. Ltd.
15.58 Florica Therapeutics
15.59 HansaBioMed Life Sciences, Ltd.
15.59.1 Products
15.59.2 Services
15.60 ILIAS Biologics, Inc.
15.60.2 Cargo Loading Process
15.60.3 Exo-Target: Platform Technology
15.61 INEXOPLAT, Inc.
15.62 Innocan Pharma
15.62.1 Cannabidiol (CBD)-Loaded Exosomes
15.63 Innovex Therapeutics, SL
15.63.1 Research & Development
15.63.2 Vaccine against Plasmodium vivax malaria (PvRexVac)
15.63.3 Vaccine against COVID-19 (ExoCoVac)
15.63.4 Vaccine against PRRSV (PrrsvExoVac)
15.64 INOVIQ, Ltd.
15.64.1 NETs Technology
15.64.2 EXO-NET Pan Exosome
15.65 Irazu Oncology
15.66 Izon Science, Ltd.
15.66.1 qEV Isolation
15.66.2 qEV Automation
15.66.3 qEV Zenco
15.66.4 Robotic System for Diagnostic Development
15.66.5 qEV Magnetic Concentration Kit
15.66.6 Tunable Resistive Pulse Sensing (TRPS)
15.67 Kimera Labs, Inc.
15.67.1 Vive
15.67.2 Luxir & Luxir+
15.68 Leading Biology, Inc.
15.69 LifeSpan Biosciences, Inc.
15.70 Lonza Group, Ltd.
15.70.1 Exosome Service
15.71 Mantra Bio
15.71.1 REVEAL
15.71.2 Partnering
15.72 Mercury Bio
15.72.1 The Chimeric yEV System
15.73 Mercy Bioanalytics
15.73.1 The Mercy Halo Test
15.74 Micregen, Ltd.
15.74.1 Secretomix
15.75 Microgentas
15.75.1 Products
15.75.1.1 Exo TFF
15.75.1.2 ExoFilter
15.75.1.3 ExoCAS-2 (Exosome Clustering and Scattering)
15.75.1.4 ExoPAS Advanced (Exosome Precipitation and Scattering)
15.75.1.5 miRQuick (Exosomal miRNA)
15.75.1.6 PIBEX System
15.75.1.7 Plant Exosomes for Cosmetics
15.75.1.8 Centella Asiatica Extracellular Vesicles (CICA EVs)
15.75.2 Services
15.76 miR Scientific
15.76.1 miR Sentinel
15.77 Mursla Bio
15.77.1 Liver EV Liquid Biopsy Platform
15.78 MyBioSource, Inc.
15.79 Nano 24 (OBCDCT24)
15.80 NanoSomiX, Inc.
15.80.1 Technology
15.81 Nanovex Biotechnologies
15.81.1 Technology
15.81.2 Synthetic Exosomes
15.82 NeurExo Sciences
15.82.1 Research & Development Programs
15.83 NeuroDex, Inc.
15.83.1 ExoSORT
15.83.2 Lumin-EV
15.83.3 Alpha-synuclein Assay
15.83.4 TDP43 Assay
15.83.5 Synaptic Protein Assay
15.83.6 Autophagy Assay
15.83.7 Biomarker Discovery Services
15.83.8 LuminEV Kit
15.84 Norgen Biotek Corporation
15.84.1 Exosome Kits
15.84.1.1 Intact Exosome Purification
15.84.1.2 RNA Isolation from Intact Exosomes
15.84.1.3 Exosome Purification, Exosome RNA and Free-Circulating RNA Isolation
15.84.1.4 RNA Isolation from Purified Intact Exosomes
15.84.1.5 Exosome Depletion
15.84.1.6 Exosome Labeling and Cleaning Kit
15.84.1.7 Isolation Services
15.84.1.8 Contract Manufacturing Services
15.85 Novaxomx GmbH
15.85.1 Technology
15.86 Novus Biologicals
15.86.1 Exosome Research Tools
15.87 NurExone Biologic, Inc.
15.87.1 ExoTherapy
15.88 Oasis Diagnostics Corporation
15.88.1 Pure.SAL
15.89 NX Prenatal, Inc.
15.89.1 Technology
15.90 OmniSpirant Therapeutics
15.90.1 OmniSome Therapeutic Platform
15.91 OncoXome, Inc.
15.91.1 OncoXome’s Exosomes
15.92 Paracrine Therapeutics Pte, Ltd.
15.92.1 Science
15.93 QIAGEN
15.93.1 exoEasy Maxi Kit
15.93.2 exoRNeasy Midi Kit
15.93.3 mercury LNA miRNA Focus PCR Panels
15.93.4 miRCURY Exosome Serum/Plasma Kit
15.94 Reactive Medical Labs
15.95 ReNeuron
15.95.1 CustomEX - A Customizable Exosome Platform
15.96 RION Aesthetics, Inc.
15.96.1 Products
15.96.1.1 INTENSE Serum
15.96.1.2 DAILY Serum
15.96.1.3 CALM Serum
15.96.1.4 HAIR Serum
15.97 Rivela Diagnostics
15.97.1 Technology
15.98 RoosterBio, Inc.
15.98.1 MSC-derived Exosomes
15.98.2 QuickShip Exosomes
15.98.3 QuickShip MSC and Exosome Media
15.98.4 XF Bioreactor MSC & EV Development Kits
15.98.5 XF Bioreactor MSC & EV Scale-Up Kits
15.98.6 XF Bioreactor MSC & EV Starter Kits
15.98.7 RoosterCollect-EV-CC
15.99 ShiftBIO
15.99.1 NSM Platform Technology
15.100 SOL Bio Corporation
15.100.1 Business Model
15.100.2 NeutraRelease Technology
15.100.3 ExoMain
15.100.4 ExoBead
15.101 SomesTech
15.101.1 Products & Solutions
15.101.1.1 ExoNP
15.101.1.2 ExoLoad
15.101.1.3 AI + DDS
15.102 Stem Cell Medicine, Ltd.
15.102.1 SCM’s Pipeline
15.103 System Biosciences
15.103.1 Products
15.103.1.1 Exosome Isolation Products
15.103.1.2 Exosome Detection Products
15.103.1.3 Exosome Quantitation Products
15.103.1.4 Exosome Labeling Kit Products
15.103.1.5 Exosome Biomarker Discovery Products
15.103.1.6 Exosome Engineering & Design Products
15.103.2 Services
15.104 Theoria Science, Inc.
15.104.1 ExoScreen Technology
15.105 TheraXyte
15.105.1 TAXY - A Programmable Drug Delivery System
15.106 Thermo Fisher Scientific
15.106.1 Exosome Products for Testing & Research
15.107 TheraXyte Bioscience
15.107.1 TAXY
15.108 The Tiny Cargo Company
15.109 TransGen Biotech, Co., Ltd.
15.109.1 Products
15.109.1.1 TransExo Cell Media Exosome Kit
15.109.1.2 TransExo Urine Exosome Kit
15.109.1.3 TransExo Serum/Plasma Exosome Kit
15.109.1.4 TransExo Serum/Plasma Exosome Total RNA Extraction Kit
15.109.1.5 TransExo Serum/Plasma Exosome Total miRNA Extraction Kit
15.110 Tymora Analytical
15.110.1 Services
15.110.1.1 Plasma Proteomics (PTMs)
15.110.1.2 Urine Proteomics
15.110.1.3 Saliva Proteomics
15.110.1.4 Tissue Proteomics
15.111 Unicyte AG
15.111.1 Technology
15.112 Urvogelbio Pvt, Ltd.
15.113 Versatope Therapeutics
15.113.1 Technology
15.113.2 Universal Influenza Vaccine
15.114 VesiCURE Therapeutics
15.114.1 modEXO Platform
15.114.2 dilEVery Delivery System
15.115 Vesigen Therapeutics, Inc.
15.115.1 ARMMs
15.115.2 Disease Areas of Focus
15.115.2.1 Ocular
15.115.2.2 Immunology
15.115.2.3 Neurology
15.115.2.4 Hematology
15.116 VivaZome Therapeutics
15.116.1 VivaZome’s Clinical Targets
15.117 ZEO ScientifiX, Inc.
15.117.1 Aesthetic Exosomes
15.117.2 PPX
15.118 Xosomix

FIGURE 2.1: Classification of Extracellular Vesicles
FIGURE 2.2: Exosome Formation
FIGURE 2.3: Exosome Uptake by Target Cells
FIGURE 2.4: Structure of an Exosome
FIGURE 2.5: Membrane Lumen Components of Exosomes
FIGURE 2.6: Classification of Exosomes by Origin
FIGURE 2.7: Exosome Isolation Methods
FIGURE 2.8: Exosomes with Loaded Therapeutics in the Lumen and Surface Display
FIGURE 3.1: Pre-Isolation Interior Modification Methods
FIGURE 3.2: Post-Isolation Interior Modification Methods
FIGURE 3.3: Surface Modification through Parent Cell
FIGURE 3.4: Direct Surface Modification
FIGURE 3.5: Pre-Isolation Interior Modification Methods
FIGURE 3.6: Post-Isolation Interior Modification Methods
FIGURE 3.7: An Engineered Exosome showing Surface and Interior Modifications
FIGURE 4.1: Number of PubMed.gov Publications, 2000-2024
FIGURE 4.2: Publication Trends of Exosome Diagnostics and Therapeutics
FIGURE 4.3: Number of PubMed Papers on Exosome Cargo-Loading by Technology
FIGURE 4.4: PubMed Papers on Exosome Isolation & Purification by Technology
FIGURE 4.6: Distribution of Exosome Publications by Disease Type
FIGURE 4.7: Exosome Publications by Cancer Type
FIGURE 5.1: Exosome Patent Publications over Time, 2000-June 2024
FIGURE 5.2: Exosome Patents: Therapeutic vs. Diagnostics
FIGURE 5.3: Exosome Patents/Patent Applications by Exosome Sources
FIGURE 5.4: Patents/Patent Applications by Isolation-Preparation Technologies
FIGURE 5.5: Patents/Patent Applications by Type of Cargo
FIGURE 5.6: Patents/Patent Applications by Cargo Loading Methods
FIGURE 5.7: Patents/Patent Applications by Therapy Area
FIGURE 5.8: Leading Assignees of Exosome Patents
FIGURE 5.9: Top Five Countries with Exosome Patents
FIGURE 6.1: Percent Share of Clinical Trials by Application
FIGURE 7.1: Schematic of Differential Ultracentrifugation
FIGURE 7.2: Schematic of Density Gradient Ultracentrifugation
FIGURE 7.3: Schematic of Tandem Configured Ultrafiltration
FIGURE 7.4: Sequential Ultrafiltration
FIGURE 7.5: Schematic of Size Exclusion Chromatography
FIGURE 7.6: Schematic of Polymer Precipitation Method
FIGURE 7.7: Schematic of Immunoaffinity Capture Method
FIGURE 7.8: Diagram of Working Principle of Microfluidic Device
FIGURE 9.1: Schematic of Incubation Method of Drug Loading
FIGURE 9.2: Schematic of Transfection Method
FIGURE 9.3: Schematic Illustration of Sonication Method
FIGURE 9.4: Schematic Illustration of the Principle of Electroporation
FIGURE 9.5: Schematic Illustration of Drug Loading by Extrusion Method
FIGURE 9.6: Schematic Illustration of Genetic Modification of Exosome
FIGURE 10.1: Schematic Illustration of the Structure of EXO-CD24
FIGURE 10.2: Aethlon’s Hemopurifier
FIGURE 10.3: Ciola’s Unique in vivo Technology
FIGURE 10.4: Schematic of EXPLOR
FIGURE 10.5: CNS Specificity of AB126
FIGURE 10.6: OmniSomes from OmniSpirant
FIGURE 10.7: EXO-101 from Exogenus
FIGURE 11.1: Great Things in Tiny Packages
FIGURE 11.2: Major Indications Focused for Diagnosis
FIGURE 11.3: LiquidScan from BioFluidica
FIGURE 11.4: Exosome Isolation by ExoEnrich
FIGURE 11.5: Features of ExoDx Prostate Test
FIGURE 11.6: ExoScreen Assay from Theoria Science
FIGURE 12.1: Exosomes in Facial Rejuvenation using DermaPen
FIGURE 12.2: Exosome Therapy for Hair Restoration
FIGURE 12.3: Exosomes in Scar Reuction
FIGURE 12.4: AnteAGE Pro System
FIGURE 12.5: ExoCR from Cartessa
FIGURE 12.6: ELEVAI enfinity
FIGURE 12.7: EXO PLUS from Exoceuticals
FIGURE 12.8: Vive from Kimera Labs
FIGURE 12.9: CALM Serum from RION Aesthetics
FIGURE 12.10: ASCE Exosomes from ExoCoBio
FIGURE 14.1: Market for the Likely-to-be Approved Exosome Therapeutics, 2029-2035
FIGURE 14.2: Global Market for Ready-to-Use Exosomes by Type, 2023
FIGURE 14.3: Global Exosome Therapy Market by Parent Cell Type, 2023
FIGURE 14.4: Global Market for Exosome Diagnostics by Geography, 2023-2031
FIGURE 14.5: Global Exosome Technologies Market by Products, 2023-2031
FIGURE 14.6: Global Market for Exosome-based Aesthetic Products by Segment
FIGURE 14.7: The Overall Exosome Market by Segment, 2031
FIGURE 15.1: Aethlon’s Hemopurifier
FIGURE 15.2: qEV Zenco for Therapeutic Development
FIGURE 15.3: Robotic System for Diagnostic Development

TABLE 2.1: Number of Molecular Contents identified in Exosomes
TABLE 2.2: Proteins Identified in Exosomes
TABLE 2.3: Common Lipid Contents of Exosomes
TABLE 2.4: Nucleic Acids Present in Cancer-Derived Exosomes
TABLE 2.5: Types of Therapeutic Cargos Loaded into Exosomes
TABLE 2.6: Differences between Cell Therapy and Exosome Therapy
TABLE 3.1: Hydrophobic Cargo Incorporated in Exosome Mmbrane
TABLE 3.2: Examples of Hydrophilic Cargo Loaded into Exosome Lumen
TABLE 5.1: Exosome Patent Applications by Jurisdiction as of June 23, 2024
TABLE 5.2: Exosome Patent Applicants
TABLE 5.2: (CONTINUED)
TABLE 5.2: (CONTINUED)
TABLE 5.3: Exosome Patent Inventors
TABLE 5.3: (CONTINUED)
TABLE 5.3: (CONTINUED)
TABLE 5.4: Exosome Patent Owners
TABLE 5.4: (CONTINUED)
TABLE 5.4: (CONTINUED)
TABLE 5.5: Legal Status of Exosome Patents as of June 22, 2024
TABLE 6.1: Exosome Clinical Trials by Phase of Study
TABLE 6.2: Exosome Clinical Trials by Funder Type
TABLE 6.3: Exosome Clinical Trials by Technology
TABLE 6.4: Current Status of Clinical Trials using Exosomes in Treating Diseases
TABLE 6.5: Clinical Trials using Exosomes for Diagnostic Studies
TABLE 6.6: Major Exosome R&D Companies
TABLE 6.7: Exosome Therapeutics in Preclinical Development
TABLE 8.1: Exosome Technology Platforms Developed by Commercial Companies
TABLE 8.1: (CONTINUED)
TABLE 10.1: Key Players in Therapeutic Exosome Research
TABLE 11.1: Most Common Targeted Exosome Biomarkers
TABLE 11.2: Exosomal Proteins for Diagnostic Applications
TABLE 11.3: Exosomal miRNAs as Cancer Diagnostic Agents
TABLE 11.4: A Sample of Exosome Diagnostic Clinical Trials
TABLE 11.5: Key Players in the Development of Exosome Diagnostics
TABLE 12.1: Key Players in Exosome-based Aesthetics
TABLE 13.1: Venture Capital Funding raised by Exosome Companies
TABLE 13.2: Partnership/Collaboration Deals in Exosome Space
TABLE 13.3: Acquisition Deals in Exosome Space
TABLE 13.4: Licensing Deals in Exosome Space
TABLE 13.5: Exosome Companies raising IPO Funds
TABLE 14.1: Likely-to-be Approved Exosome Therapeutics between 2026 and 2029
TABLE 14.2: Market for the Likely-to-be Approved Exosome Therapeutics, 2029-2035
TABLE 14.3: Global Market for Ready-to-Use Exosomes by Type, 2023-2031
TABLE 14.4: Global Exosome Therapy Market by Parent Cell Type, 2023-2031
TABLE 14.5: Global Market for Exosome Diagnostics by Geography, 2023-2031
TABLE 14.6: Global Exosome Technologies Market by Products, 2023-2031
TABLE 14.7: Global Market for Exosome-based Aesthetic Products by Segment
TABLE 14.8: The Overall Market for Exosomes
TABLE 15.1: Aegle’s Product Pipeline
TABLE 15.2: Aruna Bio’s Product Pipeline
TABLE 15.3: BreStem Therapeutics’ Product Pipeline
TABLE 15.4: Capricor’s Multi-Stage Pipeline
TABLE 15.5: Entelexo’s Pipeline
TABLE 15.6: Evox Therapeutics’ Product Pipeline
TABLE 15.7: EXO Biologic’s Product Pipeline
TABLE 15.8: EXORPHIA’s Product Pipeline
TABLE 15.9: ExoStemTech’s Pipeline Products
TABLE 15.10: ILIAS’ Product Pipeline
TABLE 15.11: INOVIQ’s Development Pipeline
TABLE 15.12: NeurExo’s Research & Development Programs
TABLE 15.13: NeuroDex’s Pipeline
TABLE 15.14: ShiftBIO’s Natural Drug Delivery Platform-based Programs
TABLE 15.15: Unicyte’s Pipeline