Theory, Instrumentation and Applications of Infrared and Raman Spectroscopy provides the essential, theoretical and practical background material that is necessary for users to understand the fundamentals of vibrational spectroscopy. Both infrared and Raman spectroscopy are covered with a current perspective that is suitable for scientists in academia and industry. The book explains basic theory, computational-statistical methods and a broad coverage of instrumental aspects that are highlighted with a wealth of applications. Sections cover basic theory, infrared absorption and Raman scattering, highlight theoretical meaning and relevance, and discuss design features and sampling.
These foundational aspects culminate in a discussion of present methods used for qualitative and quantitative analysis. Lastly, targeted current topics with a guide to relevant literature and supporting applications are discussed, including IR and Raman microscopy and imaging, process analytical IR and Raman spectroscopy, portable handheld spectroscopy, and biological applications of IR and Raman spectroscopy.
Table of Contents
1. Introduction 2. IR and Raman theory 3. Components of spectroscopic instrumentation 4. Sampling (IR and Raman) 5. Qualitative and Quantitative analysis 6. Applications of molecular modeling. using ab initio and DFT calculations/simulations of IR and Raman spectra 7. IR and Raman microscopy and imaging 8. Portable-Handheld spectroscopy 9. Process analytical IR and Raman spectroscopy 10. Biophysical applications of IR and Raman spectroscopy
Authors
Peter Larkin Spectroscopy and Materials Characterization Group, Technology Solutions, Solvay, Stamford, CT, USA. Peter J. Larkin leads Solvay's Spectroscopy and Materials Characterization group based in Stamford, Connecticut. He has more than 25 years of experience using IR, Raman, and NIR spectroscopy in the chemical and pharmaceutical industry. This includes managing research groups in R&D environments as well as directing analytical method development, validation, and transfer teams. He specializes in IR and Raman spectral interpretation, spectroscopic chemometric analyses, early phase API and chemical development support, and process analytical techniques (PAT).Dr. Larkin received his PhD from the University of Pittsburgh in 1990 using resonance Raman and vibrational circular dichroism spectroscopy to study heme proteins. Since that time he has worked in analytical departments both in the specialty chemical and pharmaceutical industries. While at American Cyanamid/Cytec Industries in Stamford, CT, Larkin received comprehensive training in IR interpretation from Dr. Norman B. Colthup. He subsequently worked at Wyeth Pharmaceutical, had a brief stint with Pfizer, lead the solid state analysis group at Bristol-Myers Squibb, and now leads the spectroscopy and materials characterization group at Solvay.
