This volume focuses on pancreas and beta cell replacement and illustrates how progress in biomaterial sciences, stem cell biology, gene editing, cell, tissue and organ bioengineering and regeneration, along with advances in xenotransplantation are revolutionizing the field. Written by the world's experts in the fields of pancreas, islet and xenotransplantation, as well as regenerative medicine, it represents a valuable educational tool for those in the fields of clinical transplantation, researchers in the field of regenerative medicine, transplant medicine, diabetes and immunology, as well as for medical and health science students, those in academia, the biotech industry and regulatory agencies working to advance the field. At the end of the book, it will become clear to the reader that beta cell replacement offers a vast array of platforms for the application of regenerative medicine technologies to transplant medicine. ?
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Table of Contents
1. Whole Pancreas Transplantation
2. Pancreas Resuscitation for Whole Pancreas Transplantation
3. DCD Normothermic Perfusion for Whole Pancreas and Islet Transplantation
4. Allo Islet Isolation
5. Auto Islet Isolation
6. Oxygenation of the Pancreas
7. Encapsulation Devices to Enhance Graft Survival
8. TG Pigs for Xenotransplantation
9. Xenoslet Cell Transplantation
10. Stem Cell Therapy for Treatment of Diabetes