Reliable, precise and accurate detection and analysis of biomarkers remains a significant challenge for clinical?researchers. Methods for the detection of biomarkers are rather complex, requiring pre-treatment steps before analysis can take place. Moreover, comparing various biomarker assays and tracing research progress in this area systematically is a challenge for researchers. The Detection of Biomarkers presents developments in biomarker detection, including methods tools and strategies, biosensor design, materials, and applications. The book presents methods, materials and procedures that are simple, precise, sensitive, selective, fast and economical, and therefore highly practical for use in clinical research scenarios. This volume situates biomarker detection in its research context and sets out future prospects for the area. Its 20 chapters offer a comprehensive coverage of biomarkers, including progress on nanotechnology, biosensor types, synthesis, immobilization, and applications in various fields. The book also demonstrates, for students, how to synthesize and immobilize biosensors for biomarker assay. It offers researchers real alternative and innovative ways to think about the field of biomarker detection, increasing the reliability, precision and accuracy of biomarker detection.
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Table of Contents
1. Introduction to biomarkers
2. Low molecular weight biomarkers: Types and detection strategies
3. Circulating miRNAs as biomarkers for non-invasive cancer diagnosis
4. Cardiac biomarkers: Definition, detection, diagnostic use and efficiency
5. Proteomic-based identification of novel biomarkers
6. Metabolomics tools for biomarker discovery: Applications in Chronic Kidney Disease
7. Electronic devices for biomarker monitoring
8. Novel advances in nanomaterial-based electrochemical sensing of the biomarker
9. Carbon nanomaterials-based electrochemical cancer biomarkers biosensors
10. Optical nanosensors based on SERS substrate for biomedical and biomarker detection applications
11. Optical smartphone-based sensing: Diagnostic of Biomarkers
12. Design of immunosensors for rapid and sensitive detection of biomarkers
13. Recent Advances in immunosensors for Healthcare
14. Impedimetric immunosensors for detection of biomarkers
15. Conducting polymers
versatile tools in analytical systems for the determination of biomarkers and biologically active compounds
16. Molecularly imprinted polymers-based biosensors for sensitive detection of biomarkers
17. Microfluidics technology: past, present and future prospects for biomarker diagnostics
18. Wearable and tattoo biosensors for disease biomarker monitoring
19. Nanomachines and nanorobotics: Improving Cancer Diagnosis and Therapy
20. Analytical Perspective on biomarkers Research: From untargeted to targeted metabolomics
