Biological Macromolecules: Bioactivity and Biomedical Applications presents a comprehensive study of biomacromolecules and their potential use in various biomedical applications. Consisting of four sections, the book begins with an overview of the key sources, properties and functions of biomacromolecules, covering the foundational knowledge required for study on the topic. It then progresses to a discussion of the various bioactive components of biomacromolecules. Individual chapters explore a range of potential bioactivities, considering the use of biomacromolecules as nutraceuticals, antioxidants, antimicrobials, anticancer agents, and antidiabetics, among others. The third section of the book focuses on specific applications of biomacromolecules, ranging from drug delivery and wound management to tissue engineering and enzyme immobilization. This focus on the various practical uses of biological macromolecules provide an interdisciplinary assessment of their function in practice. The final section explores the key challenges and future perspectives on biological macromolecules in biomedicine.
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Table of Contents
Part I: Background 1. Biological macromolecules: Sources, properties and functions 2. Structure-activity relationship of biological macromolecules 3. The importance of biological macromolecules in biomedicine 4. Modification techniques for carbohydrate Macromolecules
Part II: Bioactivity 5. Biological macromolecules as nutraceuticals 6. Biological macromolecules as antioxidants 7. Biological macromolecules as antimicrobial agents 8. Biological macromolecules from algae and their antimicrobial applications 9. Biological macromolecules acting on central nervous system 10. Biological macromolecules as antidiabetic agents 11. Biological macromolecules as anticancer agents 12. Biological macromolecules as immunomodulators 13. Biological macromolecules acting on gastrointestinal systems 14. Synthetic macromolecules with biological activity
Part III: Functional Applications 15. Biological macromolecules in drug delivery 16. Biological macromolecules in tissue engineering 17. Biological macromolecules for drug delivery in tissue engineering 18. Biological macromolecules for growth factor delivery 19. Biological macromolecules for growth factor delivery in bone regeneration 20. Biological macromolecules for nutrients delivery 21. Biological macromolecules for nucleic acid delivery 22. Biological macromolecules in cell encapsulation 23. Biological macromolecules in enzyme immobilization 24. Carbohydrates mimetics: enzyme inhibitors and target molecules in several diseases
Part IV: Others 25. Current challenging issues of biological macromolecules in biomedicine 26. Future perspectives of biological macromolecules in biomedicine
Authors
Amit Kumar Nayak Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Bhubaneswar, Odisha, India.Dr. Amit Kumar Nayak (MPharm, PhD) is working as a professor, at the Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha 'O' Anusandhan (Deemed to be University), Odisha, India. He has earned his PhD from IFTM University, Moradabad, Uttar Pradesh, India. He has over 14 years of research experiences in the field of pharmaceutics, especially in the development and characterization of novel biopolymeric and nanostructured drug delivery systems. Till date, he has authored more than 138 research and review publications in various high-impact peer-reviewed journals and 135 book chapters. He has edited/authored 23 international books to his credit. Dr. Nayak has presented his research work at several conferences. He has received University Foundation Day Research Award, 2019 and 2022 by Biju Patnaik University of Technology, Odisha. Dr. Nayak is a life member of the Association of Pharmaceutical Teachers of India (APTI) and a registered pharmacist.
Amal Kumar Dhara Department of Pharmacy, Contai Polytechnic, Government of West Bengal, Contai, Purba Medinipur, West Bengal, India. Dr. Amal Kumar Dhara (MPharm, PhD) has over 20 years of teaching and research experience in the fields of Pharmacology and Toxicology, especially in the areas of neuropharmacology and anti-inflammatory, antiulcer, and free radical scavenging activities of indigenous Indian plants. He earned his PhD in Pharmaceutical Sciences from Jadavpur University, Kolkata, West Bengal, India. Currently, Dr. Dhara works as a Lecturer in Pharmacy (Associate Professor) at Contai Polytechnic, Purba Medinipur, West Bengal, India. Dilipkumar Pal Guru Ghasidash Vishwavidyalaya. Dr. Dilipkumar Pal is an Associate Professor at the Department of Pharmaceutical Sciences, Guru Ghasidash Vishwavidyalaya, Bilaspur, India. He received his master and PhD degree from Jadavpur Universty, Kolkata, and performed post-doctoral research as Endeavour research fellow in University of Sydney, Australia. His research interests include phytochemical pharmacological evaluation of indigenous plants and natural biopolymers. He has published 177 full research papers in peer-reviewed national and international scientific journals, and contributed 115 abstracts in different national and international conferences. He has written one book and 68 book chapters and edited seven books published by reputed international publishers. Dr. Pal had received 13 national and international professional awards and has guided seven PhD and 39 master students for their dissertation thesis. He is the reviewer and Editorial Board member of 27 and 29 scientific journals, respectively. Dr Pal is the Editor-in-Chief of the research journal SPER Journal of Pharmaceutical and Biological Research.