New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Secondary Metabolites Biochemistry and Applications examines the areas of biotechnology and chemical engineering, covering aspects of plants, bacteria and machines, and using microbes as factories. The book is aimed at undergraduates, post-graduates and researchers studying microbial secondary metabolites, and is an invaluable reference source for biochemical engineers working in biotechnology, manipulating microbes, and developing new uses for bacteria and fungi. The applications of secondary metabolites in biotechnology, pharmaceuticals, diagnostics and medical device development are also extensively covered.
The book integrates the aforementioned frontline branches into an interdisciplinary research work to satisfy those working in biotechnology, chemical engineering, alternative fuel development, diagnostics and pharmaceuticals. Chapters related to important research work on applications of microbial secondary metabolites are written by specialists in the various disciplines from the international community.
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Table of Contents
Section A. Chemistry and biosynthesis 1. Peptide and peptide-derivative antibiotics 2. Polyketide derivatives 3. Other groups of bioactive products
Section B. Genetics and bioengineering 1. Preparation of high production microorganisms 2. Genetic manipulation of secondary metabolites producers 3. Bioengineering of secondary metabolites 4. Secondary metabolites: from metabolic engineering to synthetic biology/Metabolomics for secondary metabolites
Section C. Obtaining new bioactive secondary metabolites 1. Isolation from natural resources 2. Producers of bioactive compounds 3. Semi-synthetic and synthetic bioactive products 4. Hybrid bioactive products and combinatorion biosynthesis
Section D. Regulation of secondary metabolites production 1. Growth phases of microbial culture 2. Control of fermentation by basal nutrients 3. How signals from the medium are received 4. Regulation by low molecular compounds 5. Autoregulators 6. Regulation by metal ions
Section E. Resistance to secondary metabolites 1. Resistance of bioactive secondary metabolites producers 2. Resistance in pathogenic microorganisms
Authors
Vijai G. Gupta Department of Chemistry and Biotechnology, Tallinn University of Technology, Estonia. Dr Vijai G. Gupta is an Assistant Professor of Biotechnology at MITS University of India. Currently he is working as Research Scientist at National University of Ireland in Galway. Dr. Gupta's present work is focused on the development and optimization of novel Enzyme-based bioconversion systems for biorefining and bioenergy. He has been honored with several awards, including the prestigious Indian ICAR Senior Research Fellowship and Indian Young Scientist Award. He has submitted 33 new fungal nucleotide sequences and deposited 147 fungal strains in International databases. His work with Fusarium spp., Colletotrichum gloeosporioides, Penicillium spp. and Trichoderma spp. is augmented by contributions to biotechnological development, molecular diversity, secondary metabolites and industrial applicationsDr. Gupta is the editor-in-chief of the International Journal of Plant Pathology and a regional editorial board member of 8 other respected journals. He is the author of 40 journal articles and 27 book chapters. Gupta has also written and edited books and series from reputed publishers, including CRC Press, Taylor and Francis, USA; Springer, USA; Elsevier, USA; Nova Science Publisher, USA and LAP Lambert Academic Publishing, Germany. Anita Pandey G.B. Pant National Institute of Himalayan Environment and Sustainable Development, Almora, Uttarakhand, India. Dr. Anita Pandey is a Microbiologist at the G.B. Pant National Institute of Himalayan Environment and Sustainable Development in Almora, Uttarakhand, India. Her research focuses on the bioprospection of microbial diversity in the Indian Himalayan region (IHR). Specifically, her research areas of interest have included extremophiles, rhizosphere, biodegradation, fermented foods, water microbes, and plant-based antimicrobials. She has also developed microbial formulations for conservation of medicinal plant species and established a microbial culture collection in her laboratory. MSc, PhD and Postdoc scholars work in her research group.
Dr. Pandey has several recognitions to her credit, such as the National Young Woman Bioscientist Award by DBT, Govt. of India, New Delhi and Vishisht Mahila Vaigyanik Sammaan (Eminent Woman Scientist Recognition) by USERC, Govt. of Uttarakhand, India.
