Ever since the association between cancer and thrombosis was reported by Jean-Baptiste Bouillaud in the early 19th century, cancer-associated thrombosis has remained a challenging domain of cancer management. Thrombosis can at times be a lead to cancer diagnosis, while it often complicates medical situations as a coexisting disorder. In this handbook, the contributors have compiled comprehensive information on the subject to provide the reader a comprehensive review of current medical literature and guidelines for cancer-associated thrombosis.
Key Features
Thrombosis in Cancer: A Medical Professional's Guide to Cancer Associated Thrombosis is an informative handbook for a broad range of readers in medicine, including generalists, residents, and graduate-level trainees.
Key Features
- Clinically oriented text for application in healthcare settings
- Current, evidence-based literature reviews and references
- Includes guidelines on VTE prophylaxis, heparin effects and more
- Includes information about special cases
Thrombosis in Cancer: A Medical Professional's Guide to Cancer Associated Thrombosis is an informative handbook for a broad range of readers in medicine, including generalists, residents, and graduate-level trainees.
Table of Contents
Chapter 1 Overview of Cancer-Associated Thrombosis- Introduction
- Epidemiology
- Prognosis and Impact of Vte in Cancer Patients
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 2 Pathophysiology and Risk Factors for Cancer-Associated
- Thrombosis
- Pathophysiology
- Risk Factors
- Tumor Related Factors
- Treatment-Related Factors
- Surgery
- Hospitalization
- Chemotherapy, Hormonal Therapy, and Radiotherapy
- Supportive Therapy
- Patient-Related Factors
- Biomarkers
- Risk Models
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 3 Impact of Venous Thromboembolism on Cancer Survival
- Background
- Incidence
- Mortality
- Vte Recurrence
- Effect of Anticoagulation in Cancer
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 4 Occult Cancer Workup in Idiopathic Venous
- Thromboembolism
- Introduction
- Prajwal Dhakal and Nishraj Basnet
- Fawzi Abu Rous, Layan a Elkhatib and Prajwal Dhakal
- Manoj Rai
- Manoj Rai
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 5 Chemotherapy Induced Thrombosis
- Introduction
- Pathophysiology
- Prophylaxis During Chemotherapy
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 6 Catheter-Related Thrombosis in Cancer
- Introduction
- Epidemiology and Risk Factors
- Pathophysiology and Types of Crt
- Pericatheter Sheath or Fibrin Sleeve
- Intraluminal Clot
- Mural Thrombus
- Other Causes
- Clinical Presentation
- Diagnosis
- Treatment
- Removal of Catheter
- Systemic Anticoagulation
- Other Options
- Prevention of Crt in Cancer Patients
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 7 Management of Cancer-Associated Thrombosis
- Introduction
- Initial Treatment
- Anticoagulants
- Low Molecular Weight Heparin
- Factor Xa Inhibitors
- Unfractionated Heparin
- Warfarin
- Long Term Management
- Role of Direct Oral Anticoagulants
- Financial Aspects of Choosing Anticoagulation
- Mechanical Devices
- Inferior Vena Cava Filters
- Impact on Survival with Anti-Thrombotic Therapy
- Manoj Rai and Nishraj Basnet
- Prajwal Dhakal
- Lilit Karapetyan, Calvin Abro, Seda Grigoryan and Prajwal Dhakal
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 8 Special Cases in Cancer-Associated Thrombosis
- Introduction
- Vte and Thrombocytopenia
- Recurrent Vte
- Vte in Renal Impairment
- Incidental Vte in Cancer
- Myeloproliferative Disorders and Vte
- Bone Marrow Transplantation and Vte
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 9 Antitumor Effects of Heparin
- Introduction
- Types of Heparin
- Unfractionated Heparin
- Low-Molecular-Weight Heparin
- Butanoylated Heparin
- Effects of Heparin on Tumor
- Anti-Angiogenesis Effects
- Antiproliferative Effects
- Effects on Immune System
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 10 Vte Prophylaxis
- Introduction
- Risk Stratification
- Inpatient Vte Prophylaxis
- Outpatient Vte Prophylaxis
- Perioperative Vte Prophylaxis
- Society Guidelines
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Omar Albanyan and Ikponmwosa Enofe
- Samanjit Kandola and Manoj Rai
- Fawzi Abu Rous, Manoj Rai, Osama Mosalem, Layan El-Khatib, Calvin Abro And
- Abdullah Al-Abcha
- Subject Index
Author
- Supratik Rayamajhi
- Prajwal Dhakal
- Shiva Shrotriya
- Nishraj Basnet
