In this difficult period of the SARS-CoV-2 (and its variants) infection responsible for Covid-19 diseases, the importance of scientific works and reviews dealing with these viruses has never been more essential and vital.
Reports as of 20th April 2021 indicate over 141 million cases of SARS-CoV-2 infection worldwide (with over 3 million deaths recorded). This volume brings together essential data regarding prevention (vaccination), detection, and various approaches (chemotherapeutic drugs and antibodies) to the potential treatment of coronavirus infections. It presents six chapters concerning the following topics:
(1) the resistance to the spread of SARS-CoV-2 and related Covid-19 diseases within a population based on the pre-existing immunity of a high proportion of individuals as a result infection or previous vaccination
(2) the impact of the Covid-19 pandemic for the South Asian Association for Regional Cooperation (SAARC) region, comprising the Bangladesh, Bhutan, Maldives, Nepal, Pakistan, Sri Lanka, India, and Afghanistan
(3) the effect of candidate drugs chloroquine and hydroxychloroquine on QT interval in infected patients with Covid-19 diseases
(4) the antiviral potential of herbal-based immunomodulators
(5) the humoral immune response in humans based on anti-SARS-CoV-2 antibodies to treat Covid-19 diseases
(6) the various methods and strategies for diagnosing SARS-CoV-2 (and its variants) infection in hosts/humans.
This compilation should prove to be a tool of crucial importance for researchers around the world working on research revolving around coronaviruses, as well as for clinicians confronted by a growing number of patients with COVID-19.
Reports as of 20th April 2021 indicate over 141 million cases of SARS-CoV-2 infection worldwide (with over 3 million deaths recorded). This volume brings together essential data regarding prevention (vaccination), detection, and various approaches (chemotherapeutic drugs and antibodies) to the potential treatment of coronavirus infections. It presents six chapters concerning the following topics:
(1) the resistance to the spread of SARS-CoV-2 and related Covid-19 diseases within a population based on the pre-existing immunity of a high proportion of individuals as a result infection or previous vaccination
(2) the impact of the Covid-19 pandemic for the South Asian Association for Regional Cooperation (SAARC) region, comprising the Bangladesh, Bhutan, Maldives, Nepal, Pakistan, Sri Lanka, India, and Afghanistan
(3) the effect of candidate drugs chloroquine and hydroxychloroquine on QT interval in infected patients with Covid-19 diseases
(4) the antiviral potential of herbal-based immunomodulators
(5) the humoral immune response in humans based on anti-SARS-CoV-2 antibodies to treat Covid-19 diseases
(6) the various methods and strategies for diagnosing SARS-CoV-2 (and its variants) infection in hosts/humans.
This compilation should prove to be a tool of crucial importance for researchers around the world working on research revolving around coronaviruses, as well as for clinicians confronted by a growing number of patients with COVID-19.
Table of Contents
Chapter 1 Effect of Chloroquine and Hydroxychloroquine on the Qt- Interval in Patients with COVID-19: a Systematic Review
- Introduction
- Pharmacodynamics and Pharmacokinetics of Chloroquine and Hydroxychloroquine
- Effect of Chloroquine and Hydroxychloroquine Against Sars-Cov-2
- In Vitro Studies
- In Vivo Studies
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 2 COVID-19: Impact of Pandemic on Saarc Nations
- Introduction
- Statistical Analysis
- Saarc Response Against COVID-19
- Medications and Vaccines Development
- Sepsivac
- Ayush-64 and Other Ayurveda Medicines
- Mycobacterium W (Mw) Vaccine
- Convalescent Plasma Therapy
- COVID-19: Effect on Saarc Economy
- COVID-19: Impact on Saarc Environment
- COVID-19: Effect on Education Sector
- Future Course of Action
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 3 Neutralizing Antibody-Based Therapies Against COVID-19
- Introduction
- Convalescent Plasma Therapy
- Monoclonal Antibody Treatment for COVID-19
- Egg Yolk Antibodies (Igy) Against Sars-Cov-2
- Camelid Antibodies Against Sars-Cov-2
- Concluding Remarks
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Abdul Aleem, Guruprasad Mahadevaiah, Sathish Chikkabyrappa, Erik Kellison And
- Nasir Shariff
- Rohini Kanwar, Jyoti Rathee, Amit Kumar, Neena Mehta and S. K. Mehta
- Hilal Çalık, Rabia Yılmaz, Hatice Feyzan Ay, Betül Mutlu and Rabia Çakır-Koç
Chapter 4 Antiviral Potential of Immunomodulators Based Medicinal
- Plants Against Novel Coronavirus-19: Against the Pandemic
- Introduction
- Material and Methods
- A General Overview on the Novel Corona Virus-2019 and Its
- Structure
- Immunsystem and Immonomodulators
- Concept of Rasayana and Relationship Between Herbal
- Immunomodulators with Ayurveda for COVID19 Treatment, A
- Possible Route
- Alkaloids
- Glycosides
- Flavonoids
- Sapogenins
- Curcumin
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- Authors Contribution
- References
Chapter 5 Diagnostic Measures for COVID-19: Current Status And
- Advances
- Introduction
- Need for Reliable Diagnostic Tools
- Diagnostic Methods for COVID-19
- Molecular Assays for Diagnosis of COVID-19
- Cdc Influenza Sars-Cov-2 Multiplex Assay
- Cdc 2019-Ncov Rt-Pcr Diagnostic Panel
- Enzyme-Linked Immunosorbent Assay (Elisa)
- Antigen Testing
- Dna Sequencing
- National and International Policies on COVID-19 Testing
- Issues and Challenges in Diagnosis of COVID-19
- Advancements in Diagnostic Tools for COVID-19
- Patent Scenario of COVID-19 Diagnostics
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- List of Abbreviations
- References
Chapter 6 Herd Immunity: An Indirect Protection Against COVID-19
- Introduction
- Herd Immunity
- Rinki Kumari, Bhargawi Mishra, Anita Venaik and Snehalata Rai
- Aditya Narvekar, Darsh Vithlani, Ameya Chaudhari, Ratnesh Jain and Prajakta
- Dandekar
- Prashant Tiwari and Pratap Kumar Sahu
- Principle of Herd Immunity
- Developing Herd Immunity
- COVID-19
- COVID 19 and Herd Immunity
- Conclusion
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Subject Index
Author
- Jean-Marc Sabatier
