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A Comprehensive Guide to Hidradenitis Suppurativa

  • Book

  • January 2022
  • Elsevier Health Science
  • ID: 5349918
Despite being a relatively straightforward clinical diagnosis, recognition of hidradenitis suppurativa (HS) is highly variable, and clinical management is challenging and complex.�Written by the world's leading experts in HS,�A Comprehensive Guide to Hidradenitis Suppurativa�brings together�up-to-date scientific evidence�on the diagnosis,�patho-mechanisms, comorbidities, and multi-faceted medical and surgical interventions for this debilitating condition-in one convenient reference.
  • Covers�every aspect of this complex skin disorder: etiology, pathophysiology, epidemiology, medical, alternative therapies, a range of surgical options, laser treatments, and comorbidities.�

  • Discusses�specific patient populations�such as children, women of childbearing potential, and pregnant and breastfeeding women. Because HS has higher prevalence in people of�skin of color, this patient population is well-documented in the text.��

  • Offers insights into�multi-disciplinary care, patient support and education, patients at risk for rapid disease progression, and clinical and translational research.�

  • Features�procedural videos�covering laser therapies, de-roofing procedures, excision techniques,�cryoinsufflation�techniques, and special wound care material selection and techniques.�

  • Includes promising future drugs and therapies that are under investigation.

  • Identifies�evidence gaps�that provide a springboard to the future innovations in HS care to come.�

  • Edited and authored by�global experts�who have helped�co-author U.S.,�Canadian, and European guidelines on HS.��

  • Enhanced eBook version included with purchase.�Your enhanced eBook allows you to access all of the text, figures, and references from the book on a variety of devices.�

Table of Contents

Chapter # Chapter Title

Front Matter and Preface

Section 1: Introduction to HS

1 Historic Perspectives

2 Epidemiology

3 Clinical Manifestations and Phenotypes

4 Differential Diagnosis

5 Histopathology

6 Imaging Modalities

7 Clinical Evaluation

8 Comorbidities and Systemic Associations

9 Disease Complications

Section 2: Pathogenesis

10 Follicular Occlusion and Inflammation

11 Microbiome

12 Genetics and Epigenetics

Section 3: Clinician's Corner

13 Management and Outcome Measure Guidelines

14 Topical Therapeutics

15 Systemic Antibiotics

16 Non-Antibiotic Systemic Therapeutics for HS

17 Targeted Therapeutics: Biologics, Small Molecules

18 Pain and Itch Control

19 Wound Care

20 Quality of Life

21 Office-Based Non-Excision Procedures

22 Office-Based Surgical Excision

23 OR-Based Surgical Procedures

24 Laser and Light-Based Treatments

25 Other Procedural Treatments

26 Lifestyle Modifications

27 Complementary and Alternative Medicine (CAM)

Section 4: Special Populations

28 Pediatrics

29 Skin of Color

30 Women of Childbearing Age

Section 5: Combined Approach

31 HS Action Plan

32 HS Multi-Disciplinary Approach

33 HS Support Groups

Section 6: On the Horizon

34 Pipeline Therapeutics

35 The Future

Index

Authors

Vivian Y. Shi Associate Professor, Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, U.S.A.. Dr. Vivian Shi is the Director of Clinical Trials and the Eczema Specialty Clinic at the University of Arkansas for Medical Sciences. Her research and clinical interests are in complex inflammatory skin conditions, skin barrier repair, transepidermal drug delivery, and integrative dermatology. She was an integral part of the team of researchers characterizing the pathophysiology of atopic dermatitis using a transgenic interleukin-4 mouse model of atopic dermatitis. She has published over 150 peer-reviewed articles, and is on the speaker's bureau and the steering committee for the U.S. National Eczema Association and is a faculty member of the International Eczema Council. She has served as the principal investigator for numerous industry-sponsored and investigator-initiated clinical and translational studies in eczematous conditions. She regularly speaks in national and international conferences on atopic dermatitis and inflammatory skin conditions. Additionally, she is the recipient of the several prestigious awards and grants. Jennifer L. Hsiao Assistant Clinical Professor of Dermatology, Director, Hidradenitis Suppurativa Specialty Clinic, University of California, Los Angeles, California. Michelle A. Lowes Associate Professor of Clinical Investigation, The Laboratory for Investigative Dermatology, Rockefeller University, New York, New York. Iltefat H. Hamzavi Henry Ford Hospital, Clinical Associate Professor, Department of Dermatology, Wayne State University SOM; President, HS Foundation, Detroit, Michigan.