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COVID-19: Diagnosis and Management - Part I

  • Book

  • June 2021
  • Bentham Science Publishers Ltd
  • ID: 5367434
The Coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings.
This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.

Key Features:
  • Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students
  • Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19.
  • Six chapters in the first part which focus on clinical basics of COVID-19.
  • Six chapters in the second part which cover broader topics for practical infection control.
  • Multiple tables and figures which summarize and highlight important points.
  • Presents a summary of the current standards for the evaluation and diagnosis of COVID-19.
  • Features a detailed list of references, abbreviations, and symbols.

This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.

Table of Contents

Chapter 1 History of Pandemics
  • Introduction
  • The Athenian Plague
  • Plague of Justinian
  • The Black Death
  • Spanish Flu
  • Aids
  • Smallpox
  • Sars
  • Swine Flu or H1N1 Pandemic
  • Ebola
  • COVID-19
  • Origin of Coronavirus
  • Types of Coronaviruses
  • Disease Associated with Coronaviruses
  • Murine Hepatitis Virus (Mhv)
  • Central Nervous System
  • Hepatitis
  • Pneumonitis
  • Bovine Coronavirus
  • Human Coronavirus
  • Abbreviations
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 2 Introduction to COVID-19
  • Introduction
  • Genomic Structure of Coronavirus
  • Structural Proteins
  • Spike Protein
  • Small Membrane Protein
  • Membrane Protein
  • Hemagglutinin-Esterase
  • Nucleocapsid and Internal Proteins
  • Replicase Protein
  • Viral Cycle
  • Outbreaks of Coronavirus
  • Porcine Coronavirus
  • Avian Coronavirus
  • Feline Coronavirus
  • Bovine Coronavirus
  • Sunishtha, Govind Singh and Sanju Nanda
  • Hitesh Malhotra, Anjoo Kamboj and Peeyush Kaushik
  • Murine Coronavirus
  • Human Coronavirus
  • Sars-Cov
  • Mers-Cov
  • COVID-19
  • Introduction
  • Chronology of COVID-19
  • Symptoms
  • Transmission
  • Treatment
  • List of Abbreviations
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 3 COVID-19: Epidemiology
  • Introduction
  • Geographical Distribution
  • Global Epidemiology of COVID-19
  • Effect of Age, Sex and Other Factors on COVID-19-Related Deaths
  • COVID-19 Case Comparisons in Different Region of World (World
  • Health Organization, 2020)
  • COVID-19 in India
  • Report by Icmr on COVID-19 About Containment Zone in India
  • National Responses on COVID-19 Worldwide
  • Asia
  • China
  • South Korea
  • Middle Eastern
  • Iran
  • Europe
  • Spain
  • France
  • North America
  • United States
  • South America
  • Africa
  • Oceania
  • Effect of Lockdown on COVID-19 Cases in Top Ten Most Affected
  • Countries of World
  • The Role of Who and Ingos for Providing Data in COVID-19
  • Outcomes from Some Published Reports on COVID-19 Epidemiology 74
  • Herd Immunity-COVID-19
  • Conclusion
  • List of Abbreviations
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • Kamya Goyal, Shammy Jindal, Tarun Kumar, Jugnu Goyal, Reena Sharma,
  • Ravinder Singh and Samir Mehndiratta
  • References

Chapter 4 Pathophysiology
  • Introduction
  • Transmission of Cov
  • Virus Life Cycle
  • Role of Structural Proteins in the Pathogenesis
  • A. Spike Protein
  • B. Hemagglutinin-Esterase (He) Protein
  • C. Membrane (M) Protein
  • D. Small Envelop (E) Protein
  • E. Nucleocapsid (N) Protein and Internal (I) Protein
  • F. Replicase Proteins
  • G. Cov Associated Protein
  • Pathophysiology from a Cell Biology Perspective
  • Phase I. Asymptomatic Stage (First 1-2 Days of Infection)
  • Phase Ii. Upper Airway and Conducting Airway Response (Next Few Days)
  • Phase Iii. Hypoxia, Ground-Glass Infiltrates, Progression to Ards
  • Conclusion
  • List of Abbreviations
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 5 Clinical Presentation and Comorbidities
  • Introduction
  • Clinical Presentations of COVID-19 Infection
  • Inter-Individual Variations in Clinical Presentations due To
  • Differential Susceptibility Towards COVID-19
  • Neonates or Newborns (Upto 1 Month); Infants (1 Month-2 Years), Children (2-10 Years) 120
  • Adolescent (11-19 Years), Young (20-35 Years) and Middle Aged (36-59 Years) Patients 128
  • Elderly (>60 Years) and Older (>80 Years) Patients
  • Ace2
  • Gender
  • Blood Group
  • Previous Immunization
  • Comorbidity
  • Conclusion
  • List of Abbreviations
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References

Chapter 6 Diagnosis
  • COVID-19: a Pandemic Disease
  • COVID-19: Early Detection Based on Symptoms
  • Clinical Analysis
  • Anirban Ghosh and Shamsher Singh
  • Jasleen Kaur, Baljinder Singh, Bikash Medhi and Gurpreet Kaur
  • Richa Deshpande, Aishwarya Joshi, Nikunj Tandel and Rajeev K. Tyagi
  • Hematological Analysis
  • Chest Ct
  • COVID-19: Molecular Detection of Virus
  • Rt-Pcr Based Assays
  • Loop Mediated Isothermal Amplification (Lamp)
  • Crispr-Isothermal Amplification Based Assays
  • Microarrays
  • Metagenomic Sequencing Based Methods
  • Gold Nanoparticles-Based Colorimetric Assay
  • COVID-19: Seriological and Immunological Based Detection
  • Biomarker Identification: Approach of Serological Platform
  • Antibody Biomarkers
  • Antigen Biomarkers
  • Procalcitonin and Interleukin-6 as Prognostic COVID-19 Biomarkers
  • Serological and Immunological Assays
  • Enzyme-Linked Immunosorbent Assay (Elisa)
  • Lateral Flow Immunoassay
  • Neutralization Assays
  • Luminescence-Based Immunoassays
  • Biosensor Tests
  • Rapid Antigen Tests
  • Concluding Remarks
  • List of Abbreviations
  • Consent for Publication
  • Conflict of Interest
  • Acknowledgements
  • References
  • Subject Index

Author

  • Neeraj Mittal
  • Sanjay Kumar Bhadada
  • O. P. Katare
  • Varun Garg