The coronavirus disease 2019 (COVID-19) outbreak has spread throughout the globe and much time has passed since it was declared as a pandemic by the World Health Organization (WHO). COVID-19: Diagnosis and Management provides clinicians and scholars all the information on this disease in 2 volumes. Readers will find a concise and visual reference for this viral disease and will be equipped with the knowledge to assess and manage Sar-Cov-2 infection cases in clinical settings.
This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.
Key Features:
This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.
This book is divided into two parts (I and II). Part I provides comprehensive information about 1) History of Coronaviruses, 2) Epidemiology of COVID-19, 3) Clinical presentation of this viral disease and 4) COVID-19 diagnosis. Part II covers broader topics about this communicable disease including 1) the prevention and treatment methodology, 2) mortality and long-term complications, 3) COVID-19 vaccines and future perspectives.
Key Features:
- Covers all the aspects of COVID-19 making this a perfect textbook for virology and medical students
- Chapter wise description and segregation of topics from pathophysiology to diagnosis and management of COVID-19.
- Six chapters in the first part which focus on clinical basics of COVID-19.
- Six chapters in the second part which cover broader topics for practical infection control.
- Multiple tables and figures which summarize and highlight important points.
- Presents a summary of the current standards for the evaluation and diagnosis of COVID-19.
- Features a detailed list of references, abbreviations, and symbols.
This book is an essential textbook reference for medical students, scientists (virologists, pulmonologists) and public health officials who are required to understand COVDI-19 diagnosis and management as part of their clinical training or professional work.
Table of Contents
Chapter 1 Prevention of COVID-19: Facts to Overcome the Myths- Introduction
- Measures to Prevent the Spread, Associated Myths and Facts
- Personal Protective Equipment (Ppe)
- Head Covers
- Face Shield
- Mask
- Goggles
- Gloves
- Shoe Covers
- Gowns or Coveralls
- Sanitization and Disinfection
- Hand Hygiene
- For Public
- Prevention of COVID-19 Among Frontline Healthcare Workers
- Cleaning of Vegetables-Fruits
- Safe Handling of Currency and Paper Documents
- Cough or Respiratory Etiquettes
- Precautions to be Taken while Coughing/Sneezing or Any Physical Contact
- Spitting or Littering in Public
- Disinfection of Public Places
- Disposal and Disinfection of Ppes
- Water Treatment and Waste Management
- Management of Water and Faecal Waste
- Safety of Water Supplies
- Social Measures
- Physical Distancing
- Quarantine and Isolation
- Home Quarantine
- Institutional Quarantine
- Staff Guidelines
- Utility Guidelines
- Lockdown and Travel Restrictions
- Zonal Classification of the Geography
- Prophylaxis for COVID-19
- Dietary Recommendations for the Prevention of COVID-19
- General Measures
- Medicinal Plant Measures/Procedures
- Medical Prophylaxis for Healthcare Workers and Contacts of a Positive Patient
- Regular Screening
- Precautions for Travel
- Conclusion
- List of Abbreviations
- Rajesh Kumar, Mangesh Pradeep Kulkarni, Sheetu Wadhwa and Soundappan Kathirvel
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 2 Current Treatment Methods for Coronavirus Disease-19
- Introduction
- Overview of Various Treatment Strategies for COVID-19
- Hydroxychloroquine
- Hcq in Treatment of COVID-19
- Remdesivir
- Remdesivir in Treatment of COVID-19
- Lopinavir/Ritonavir
- Lopinavir/Ritonavir in Treatment of COVID-19
- Favipiravir
- Favipiravir in Treatment of COVID-19
- Azithromycin (Az)
- Az in COVID-19 Treatment
- Arbidol
- Arbidol in Treatment of COVID-19
- Ribavirin
- Ribavirin in COVID-19 Treatment
- Teicoplanin
- Teicoplanin in COVID-19 Treatment
- Ivermectin
- Ivermectin in Treatment of COVID-19
- Nitazoxanide
- Nitazoxanide in COVID-19 Treatment
- Corticosteroids
- Corticosteroids in the Treatment of COVID-19
- Immuno Modulating Agents-Interferons (Ifn's)
- Ifn's in Treatment of COVID-19
- Monoclonal Antibody Therapy
- 80R Immunoglobulin G1 (Igg1)
- Cr3014
- Monoclonal Antibody Therapy in COVID-19 Treatment
- Tocilizumab
- Sarilumab
- Limitations and Suggestions Regarding Mab's
- Triple Therapy
- Miscellaneous Drugs
- Herbal Drugs for COVID-19
- Glycyrrhizin
- Glycyrrhizin in COVID-19
- Hesperetin
- Baicalin
- Scutellarin
- Plasma Therapy
- Plasma Therapy in the Treatment of COVID-19
- Kuldeep Kumar, Sonal, Pankaj Bhatia, Dhandeep Singh, Amteshwar S. Jaggi And Nirmal Singh
- Potential of Stem Cell Therapy in COVID-19
- Bcg Vaccine
- Various Regulatory Guidelines Given by Nih (National Institute Of Health) for Treatment of COVID-19
- Conclusion
- List of Abbreviations
- Authors Contribution
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 3 COVID-19 and Mortality
- Introduction
- Representing Mortality - Mortality Rate Vs. Case-Fatality Rate
- Fallacies in Estimating Mortality Using Case-Fatality Rate
- Reporting COVID-19-Related Deaths
- Comparing Case-Fatality Rates of COVID-19 with Other Related
- Viral Diseases
- Comparing COVID-19 Case-Fatality Rates Among Various Nations
- Causes of Death in COVID-19
- Parameters Predicting Mortality in COVID-19
- Clinical Parameters
- Age
- Gender
- Symptoms
- Complications
- Comorbid Illness
- Smoking
- Secondary Infections
- Laboratory Parameters
- Conclusion
- Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 4 Long Term Complications of COVID-19
- Introduction
- Long Term Complications of COVID-19
- Complications of COVID-19 in Various Diseases
- Diabetes Mellitus (Dm)
- Hematological Complications
- Cardiovascular Diseases
- Central Nervous System Complications
- Viral Encephalitis
- Infectious Toxic Encephalopathy and Cerebrovascular Disease
- Chronic Kidney Disease (Ckd)
- Rimesh Pal and Sanjay Kumar Bhadada
- Ankita Sood, Bimlesh Kumar Indu Melkani, Archit Sood, Pankaj Prashar, Anamika Gautam
- Kardam Joshi and Dhara Patel
- Asthma and Respiratory Disorders
- Rheumatoid Arthritis (Ra)
- Conclusion
- Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 5 Vaccine Development
- COVID-19: Vaccine Development
- COVID-19 Vaccine Development: Modulating the Host Immune
- System
- Types of Vaccines and Their Characteristics
- Live-Attenuated Virus and Inactivated Whole Virus Vaccines
- Subunit Vaccines
- Vaccines Based on Virus-Like Particles (Vlps)
- Viral Vector-Based Vaccines
- Dna Vaccines
- Novel Approaches: Usage of Multidisciplinary Fields
- Serum Albumin Strategy
- Natural Product (Plant) Based Technology
- Nanotechnology and Material Science
- Mrna Based Approaches
- Animal Models to Test the Immunogenic Potential of Candidate
- Vaccine Antigens
- Animal Models Currently in Practice
- Humanized Mice Models
- Novel Approach of Using Zebrafish (Their Advantages)
- Current Status of Vaccine Development
- Bench to Bedside: Obstacles and Outcomes
- Lessons from Previous Vaccine Development
- List of Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
Chapter 6 The Future of COVID-19 Treatment
- Introduction
- Drugs Affecting Viral Replication and Translation in COVID-19
- Disease
- Drugs Interfering with Inflammation and Overcoming Cytokine
- Storm in COVID-19 Disease
- Anticancer Drugs in the Treatment of COVID-19 Disease
- Antiparasitic, Antiprotozoal, and Antifungal Drugs in the Treatment of COVID-19 Disease
- Drugs Affecting the Renin-Angiotensin-Aldosterone System In
- COVID-19
- Priya Sha Rma, Shivani Joshi, Aishwarya Joshi, Nikunj Tandel and Rajeev K.
- Tyagi
- Sahil Arora, Manvendra Kumar, Gaurav Joshi and Raj Kumar
- Miscellaneous
- Discussion and Conclusion
- Abbreviations
- Consent for Publication
- Conflict of Interest
- Acknowledgements
- References
- Subject Index
Author
- Neeraj Mittal
- Sanjay Kumar Bhadada
- O. P. Katare
- Varun Garg