Role of Nutrigenomics in Modern-day Healthcare and Drug Discovery presents novel insights into how these tools can be applied in the study of nutrient-gene interaction for the management of certain disease conditions without using synthetic drugs or other treatments that come with side effects. Divided into three parts, Part I presents chapters that give background information of the subject while laying a framework for other chapters to follow. Part II presents chapters that discuss the role of nutrigenomics in healthcare, while Part III presents chapters that discuss the role of nutrigenomics in modern day drug discovery.
Written by a global team of experts from key institutions around the world, this book is useful for drug developers, medicinal chemists, public health scientists, molecular biologists, biochemists, toxicologists and food scientists.
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Table of Contents
I. Foundational Information 1. General Principles in Nutrigenomics and Nutrigenetics 2. Nutrigenomics and Nutrigenetics: Importance in Health and Diseases 3. Nutrigenomics Research: Methods and Applications
II. Role of Nutrigenomics in Healthcare 4. Role of Nutrigenomics in Diabetes Care and Prevention 5. Role of Nutrigenomics in Obesity, Hypertension and Cardiovascular Diseaseson 6. Nutrigenomics in the Management and Prevention of Wasting, Stunting and other Nutritional Disorders 7. Nutrigenomics in the Management and Prevention of Cancer 8. Nutrigenomics in the Management and Prevention of Metabolic Diseases
III. Nutrigenomics and Drug Discovery 9. Bioactive Compounds of Nutrigenomic Importance 10. Roles of Dietary Compounds in DNA methylation 11. Roles of Dietary Compounds in Histone modification 12. Dietary Compounds as Inhibitors of DNA Methyltransferases and Histone Methyltransferases 13. Role of Bioactive Compounds in Diabetes Care and Prevention 14. Role of Bioactive Compounds in Nutritional Disorders 15. Role of Bioactive Compounds in Cancer Care and Prevention 16. Role of Bioactive Compounds in Obesity, Hypertension and Cardiovascular Diseases 17. Role of Bioactive Compounds in Metabolic Diseases 18. Regulations and Ethical Considerations in Nutrigenomics Research
Authors
Genevieve Dable-Tupas Associate Professor, Research Center, College of Medicine, Davao Medical School Foundation, Inc, Davao City, Philippines. Genevieve Dable Tupas, MD, MMCE, FPPS, FPSECP is an Associate Professor at the Research Center, College of Medicine, Davao Medical School Foundation, Inc, Davao City, Philippines. Her research interests include natural products research, clinical epidemiology, and their translation to benefit the community. Chukwuebuka Egbuna Chukwuemeka Odumegwu Ojukwu University, Anambra State, Nigeria.Chukwuebuka Egbuna (PhD) is a chartered chemist and academic researcher. He is a member of the Institute of Chartered Chemists of Nigeria (ICCON), the Nigerian Society of Biochemistry and Molecular Biology (NSBMB), and the Royal Society of Chemistry (RSC) (United Kingdom). Dr. Egbuna is the founder and editor of the Elsevier book series on Drug Discovery Update. The series includes books, monographs, and edited collections from all areas of drug discovery including emerging therapeutic claims for the treatment of diseases. He has published research articles in many international journals of repute and is ranked among the top 500 Nigerian scientists in SciVal/SCOPUS. He has edited more than 25 books with Elsevier, Springer, Wiley, and Taylor & Francis. His most recent book is the three volume Coronavirus Drug Discovery, published by Elsevier. Dr. Egbuna is the founder and the publishing director of IPS Intelligentsia Publishing Services.
