New Frontiers and Applications of Synthetic Biology presents a collection of chapters from eminent synthetic biologists across the globe who have established experience and expertise working with synthetic biology. This book offers several important areas of synthetic biology which allow us to read and understand easily. It covers the introduction of synthetic biology and design of promoter, new DNA synthesis and sequencing technology, genome assembly, minimal cells, small synthetic RNA, directed evolution, protein engineering, computational tools, de novo synthesis, phage engineering, a sensor for microorganisms, next-generation diagnostic tools, CRISPR-Cas systems, and more.
This book is a good source for not only researchers in designing synthetic biology, but also for researchers, students, synthetic biologists, metabolic engineers, genome engineers, clinicians, industrialists, stakeholders and policymakers interested in harnessing the potential of synthetic biology in many areas.
Please Note: This is an On Demand product, delivery may take up to 11 working days after payment has been received.
Table of Contents
1. An introduction to advanced technologies in synthetic biologyVijai Singh, Gargi Bhattacharjee, Nisarg Gohil, Rupesh Maurya, Navya L. Lam and Khalid J. Alzahrani
2. Design and characterization of synthetic promoters
Boris Kirov and Slavil Peykov
3. Recent development in DNA synthesis technology
Indra Mani
4. Advances, challenges, and opportunities in DNA sequencing technology
Francisco J. Enguita and Ana Lucia Leitao
5. Recent developments in genome design and assembly tools
Carlos Barreiro and Carlos Garcia-Estrada
6. Design, building, and challenges in synthetic genomics
Mansoor A. Siddiqui, Ashima Sharma and Syed Shams Yazdani
7. Synthetic minimal cells and their applications
Ali Yazdizadeh Kharrazi, Amir Zare, Nils Chapin, Seyedkhashayar Ghavami and Amir Pandi
8. Small RNA-based systems for sensing and therapeutic applications
Robert Penchovsky, Georgi Y. Miloshev, Nikolet Pavlova, Katya B. Popova, Aikaterini Valsamatzi-Panagiotou, Lozena A. Otcheva and Martina Traykovska
9. High-throughput navigation of the sequence space
Alaksh Choudhury
10. Advances in protein engineering and its application in synthetic biology
Rongming Liu, Liya Liang, Maria Priscila Lacerda, Emily F. Freed and Carrie A. Eckert
11. Computational tools for design of synthetic genetic circuits
Archit Devarajan, Dhwani Gupta, Kushika Mitra, Shalini S. Deb and Shamlan M.S. Reshamwala
12. Computational tools for synthetic gene optimization
Numaan Cheema, Georgios Papamichail and Dimitris Papamichail
13. De novo design and synthesis of biomolecules
Subha Sankar Paul, Debarun Dhali, Yazen Yaseen, Upasana Basu, Shilpa Pal, Nihal Mohammed and Heykel Trabelsi
14. A retrobiosynthetic approach for production, conversion, sensing, dynamic regulation and degradation of molecules
Pablo Carbonell
15. Advances in engineering of bacteriophages for therapeutic applications
Christian M�ller-Olsen, Gurneet K. Dhanoa, Tamas Feher and Antonia P. Sagona
16. Design of synthetic biology for the detection of microorganisms
Dong-Dong Yang, Jake Flood, Rongming Liu and Susu He
17. Design of synthetic biological devices for detection and targeting human diseases
Nedim Haciosmanoglu, Sila Kose, Julian Ostaku, Ilkay Cisil Koksaldi, Behide Saltepe and Urartu Ozgur Safak Seker
18. Engineering cell-based therapies
Juan Luis Blazquez-Roman, Mara Pisani and Velia Siciliano
19. Development of next-generation diagnostic tools using synthetic biology
Elizabeth J. Vojvoda, Logan R. Burrington and Javin P. Oza
20. Advances and application of CRISPR-Cas systems
Rongming Liu, Liya Liang, Margaret Habib, Emily F. Freed and Carrie A. Eckert
21. Synthetic biology for smart drug biosynthesis and delivery
Srinivasan Ganesh Kumar, Ashok Ganesan and Shashi Kumar
22. Design and applications of self-assembled soft living materials using synthetic biology
Gokce Ozkul, Merve Yavuz, Nedim Haciosmanoglu, Busra Merve Kirpat and Urartu Ozgur Safak Seker
23. Synthetic gene circuits for higher-order information processing
Kathakali Sarkar and Sangram Bagh
24. Cell-free synthetic biology as an emerging biotechnology
Seok Hoon Hong and Ana Serratosa Fernandez-Baca
25. Recent development and applications of xeno nucleic acids
Rupesh Maurya, Nisarg Gohil, Gargi Bhattacharjee, Navya L. Lam, Khalid J. Alzahrani and Vijai Singh
26. Developments in the use of microfluidics in synthetic biology
Laila A. Damiati, Safa A. Damiati and Samar Damiati
27. Implications of synthetic biology research and development: a structured ethical analysis
Kevin Smith
Authors
Vijai Singh Department of Biosciences, School of Science, Indrashil University, Rajpur, Mehsana, India.Dr Vijai Singh is a Professor and Dean (Research & Innovation) at School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. He was an Associate Professor in the Department of Biosciences, School of Sciences, Indrashil University, Rajpur, Mehsana, Gujarat, India. Prior this this, he was an Assistant Professor in the Department of Biological Sciences and Biotechnology at the Institute of Advanced Research, Gandhinagar, India and also an Assistant Professor in the Department of Biotechnology at the Invertis University, Bareilly, India. Prior to that, he was a Postdoctoral Fellow in the Synthetic Biology Group at the Institute of Systems and Synthetic Biology, Paris, France and School of Energy & Chemical Engineering at the Ulsan National Institute of Science and Technology, Ulsan, South Korea. He received his Ph.D. in Biotechnology from the National Bureau of Fish Genetic Resources, Uttar Pradesh Technical University, Lucknow, India with a research focus on the development of molecular and immunoassays for diagnosis of Aeromonas hydrophila. His research interests are focused on building novel biosynthetic pathways for production of medically and industrially important biomolecules. Additionally, his laboratory is working on CRISPR-Cas9 tools for genome editing. He has more than 11 years of research and teaching experience in synthetic biology, metabolic engineering, bioinformatics, microbiology, and industrial microbiology. He has published 100 articles, 70 chapters, 15 books and 3 patents. He serves as an associate editor, editorial board member, and reviewer of several peer-reviewed journals. He is also a member of the Board of Study and Academic Council of Indrashil University and is the Member Secretary of the Institutional Biosafety Committee (IBSC) at the same University.
