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Provides a clear framework for a better understanding of the clinical and histopathologic appearances of more than 270 nonneoplastic entities, covering every organ system with a focus on reactive, infectious, congenital, and genetic conditions�
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Covers significant advances in this complex field, including recent molecular discoveries and updated disease entities, new information on multiple immunologic disorders, changes and expansions to several classification systems (such as WHO, Banff, and ISSVA), and updates in other scoring systems�
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Contains new chapters on manifestations of pediatric COVID-19 infection, tumoral calcinosis, multiple skeletal dysplasia, skeletal muscle, collagenous gastritis and colitis, adenovirus appendicitis, intestinal pseudoobstruction, disorders of sexual development, and Kikuchi disease�
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Includes approximately 3,000 high-quality clinical and histologic images, gross pathology images, radiologic images, and full-color illustrations to help practicing and in-training pathologists reach a confident diagnosis-as well as nearly 200 additional images online�
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Employs consistently templated chapters and bulleted content for quick, expert reference at the point of care�
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Includes an eBook version that enables you to access all text, figures, and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud�
Table of Contents
Skin
Spongiotic and Psoriasiform Dermatoses
1 Pityriasis Rosea
2 Contact Dermatitis
3 Atopic Dermatitis
4 Perniosis
5 Seborrheic Dermatitis
Inflammatory/Interface Dermatoses
6 Erythema Multiforme and Related Disorders
7 Pityriasis Lichenoides
Vesicobullous Dermatoses
8 Acropustulosis of Infancy
9 Dermatitis Herpetiformis
10 Epidermolysis Bullosa-Inherited
11 Erythema Toxicum Neonatorum
12 Hailey-Hailey Disease
13 Chronic Bullous Disease of Childhood
14 Transient Neonatal Pustular Melanosis
Vascular and Related Diseases
15 Urticaria and Variants
16 Leukocytoclastic Vasculitis
Paniculitides
17 Erythema Nodosum
18 Subcutaneous Fat Necrosis of the Newborn
19 Sclerema Neonatorum
Connective Tissue
20 Lupus Erythematosus
21 Morphea/Scleroderma
22 Dermatomyositis
Metabolic/Deposition Diseases
23 Calcinosis Cutis
Noninfectious Granulomatous Diseases
24 Chalazion
25 Granuloma Annulare
Pilosebaceous Disease
26 Acne Vulgaris
Alopecias
27 Trichotillomania
Disorders of Epidermal Maturation and Keratinization
28 Ichthyosis
29 Darier Disease
30 Porokeratosis
31 Incontinentia Pigmenti
Disorder of Collagen
32 Aplasia Cutis Congenita
Bacterial Infections
33 Impetigo
34 Staphylococcal Scalded Skin Syndrome
35 Ecthyma
36 Necrotizing Fasciitis
37 Cat Scratch Disease
38 Atypical Mycobacterial Infections
Viral Infections
39 Molluscum Contagiosum
40 Herpesvirus
Fungal Infections
41 Candidiasis
Arthropods/Parasites
42 Bite Reactions
43 Scabies
Cysts
44 Epidermal Inclusion Cyst
45 Dermoid Cyst
Bone and Joint
Congenital/Genetic/Hereditary
46 Osteogenesis Imperfecta
47 Thanatophoric Dysplasia
Trauma/Injury/Reactive
48 Bone Fracture and Repair
49 Osteomyelitis
51 Stress and the Costochondral Junction
52 Juvenile Idiopathic Arthritis
Skeletal Muscle
Congenital/Genetic Hereditary
53 Spinal Muscular Atrophy
54 X-linked Muscular Dystrophy: Duchenne and Becker
Central Nervous System
Congenital/Genetic/Hereditary
55 Cerebral Heterotopia and Ectopia
56 Cortical Dysplasia
57 Encephalocele
58 Myelomeningocele
59 Tethered Cord
60 Arteriovenous Malformation
61 Carvernous Hemangioma
Trauma/Injury/Reactive
63 Hypoxic Ischemic Encephalopathy
64 Periventricular Leukomalacia
65 Arachnoid Cysts
66 Meningioangiomatosis
67 Germinal Matrix Hemorrhage
Infectious
68 Bacterial Meningoencephalitis
69 Fungal Meningoencephalitis
70 Viral Meningoencephalitis
71 Protozoal Meningoencephalitis
Endocrine System
Congenital/Genetic/Hereditary
72 Adrenal Cytomegaly
73 Adrenal Heterotopia
74 Adrenal Hypoplasia and Malformations
75 Adrenal Cortical Hyperplasia
76 Dyshormonogenetic Goiter
77 Ectopic Thyroid
78 Thyroglossal Duct Cyst
79 "Cystic Fibrosis, Pancreas"
Trauma/Injury/Reactive
80 Stress Reactions in the Adrenal Gland
81 Hemorrhagic Necrosis of the Adrenal Gland
82 Chronic Lymphocytic Thyroiditis
83 Graves Disease
84 Hypertrophy of Pancreatic Islets
Respiratory
Congenital/Genetic/Hereditary
85 Bronchogenic Cyst
86 Congenital Alveolar Capillary Dysplasia
87 Congenital Lobar Emphysema
88 Congenital Pulmonary Lymphangiectasis
89 Diffuse Pulmonary Lymphangiomatosis
90 Congenital Pulmonary Airway Malformation
91 Congenital Surfactant Deficiency
92 Cystic Fibrosis
93 Sequestrations
Trauma/Injury/Reactive
94 Aspiration
95 Asthma
96 Bronchopulmonary Dysplasia
97 Hyaline Membrane Disease
98 Interstitial Pulmonary Emphysema
99 Persistent Pulmonary Hypertension
100 Idiopathic Pulmonary Hemosiderosis
101 Pulmonary Venoocclusive Disease
102 Nonspecific Interstitial Pneumonia
103 Extrinsic Allergic Alveolitis
104 Eosinophilic Pneumonia
Infectious
105 Adenovirus
106 Human Metapneumovirus
107 Respiratory Syncytial Virus
108 Neuroendocrine Cell Hyperplasia of Infancy
Cardiovascular
Congenital/Genetic/Hereditary
109 Arrhythmogenic Right Ventricular Dysplasia
110 Hypertrophic Cardiomyopathy
111 Dilated Cardiomyopathy
112 Fabry Disease
113 Fatty Acid Metabolic Disorders
114 Glycogen Storage Disease
115 Mitochondrial Myopathies
Trauma/Injury/Reactive
116 Endocardial Fibroelastosis
Infectious
117 Lymphocytic Myocarditis
118 Acute Pericarditis
119 Acute Rheumatic Fever
120 Kawasaki Disease
Alimentary Canal
Esophagus
Congenital/Genetic/Hereditary
121 Inlet Patch
122 Tracheoesophageal Fistula/Esophageal Atresia
123 Esophageal Duplication Cyst
Trauma/Injury/Reactive
124 Gastroesophageal Reflux Disease
125 Eosinophilic Esophagitis
Infectious
126 Herpes Simplex Virus
127 Candida
Stomach
Trauma/Injury/Reactive
128 Chemical (Reactive) Gastropathies
129 Chronic Gastritis
130 Granulomatous Gastritis
131 Lymphocytic Gastritis
132 Eosinophilic Gastroenteritis
133 Fundic Gland Polyp
Infectious
134 Helicobacter Pylori
135 Helicobacter Heilmannii
Small Bowel
Congenital/Genetic/Hereditary
136 Small Intestine Duplication Cyst
137 Ectopic Pancreas
138 Gastric Heterotopia
139 Meckel Diverticulum
140 Microvillous Inclusion Disease
141 Primary Intestinal Lymphangiectasia
142 Abetalipoproteinemia
143 Tufting Enteropathy
144 Autoimmune Enterocolitis
Inflammatory/Immune Dysfunction
145 Celiac Disease
146 Common Variable Immunodeficiency
Infectious
147 Giardia
148 Cryptosporidium
Appendix
149 Acute Appendicitis
150 Granulomatous Appendicitis
151 Enterobius Vermicularis Appendicitis
152 Fibrous Obliteration
Colon
Congenital/Genetic/Hereditary
153 "Cystic Fibrosis, Intestinal"
154 "Colonic Duplications, Cysts, and Congenital Diverticula"
155 Hirschsprung Disease
Trauma/Injury/Reactive
156 Diversion Colitis
157 Pneumatosis Intestinalis
158 Solitary Rectal Ulcer Syndrome/Mucosal Prolapse
159 Necrotizing Enterocolitis
Inflammatoyr/Immune Dysfunction
160 Eosinophilic/Allergic Colitis
161 Focal Active Colitis
162 Crohn Disease
163 Ulcerative Colitis
Infectious
164 Cytomegalovirus
165 Entamoeba Histolytica
166 Adenovirus
167 Acute Self-Limited Infectious Colitis
168 Pseudomembranous Colitis
Liver/Gallbladder
Congenital/Genetic/Hereditary
169 Congenital Hepatic Fibrosis
170 Caroli Disease
171 Cystic Fibrosis, Hepatic
172 Dubin-Johnson Syndrome
173 Gilbert Disease
174 Progressive Familial Intrahepatic Cholestasis
175 Biliary Atresia
176 Paucity of Intrahepatic Bile Ducts (Syndromic)
177 Paucity of Intrahepatic Bile Ducts (Nonsyndromic)
178 Autoimmune Hepatitis
179 Alpha-1-Antitrypsin Deficiency
180 Glycogen Storage Diseases
181 Niemann-Pick Disease
182 Tyrosinemia
183 Gaucher Disease
184 Neonatal Hemochromatosis
185 Wilson Disease
186 Choledochal Cyst
Trauma/Injury/Reactive
187 Total Parenteral Nutrition Injury
188 Idiopathic Neonatal Hepatitis
189 Reye Syndrome
190 NASH
191 Primary Sclerosing Cholangitis
192 Venooclusive Disease
193 Drug-Related Acute Hepatitis
Infectious
194 Acute Viral Hepatitis
195 Epstein-Barr Virus
196 Herpes Simplex Virus
197 Cytomegalovirus
Genitourinary
Kidney/Urinary Tract
Glomerular Diseases
198 Congenital Nephrotic Syndrome
199 Diffuse Mesangial Sclerosis
200 Minimal Change Disease
201 Focal Segmental Glomerulosclerosis
202 Acute Postinfectious Glomerulonephritis
203 Membranoproliferative Glomerulonephritis
204 C3 Glomerulonephritis
205 Dense Deposit Dense
206 Lupus Nephritis
207 IgA Nephropathy
208 Henoch-Schonlein Purpura Nephritis
209 Thin Basement Membrane Nephropathy
210 Alport Syndrome
Tubulointerstitial Disease
211 Acute Tubular Necrosis
212 Acute Pyelonephritis
213 Tubulointerstitial Nephritis
214 Primary Hyperoxaluria
Vascular Diseases
215 Fibromuscular Dysplasia (Renal Artery Stenosis)
216 "Hemolytic Uremic Syndrome, Infection-Related and Atypical"
217 "Vasculitis, ANCA-Related"
Cystic and Developmental Diseases
218 Reflux Nephropathy
219 "Polycystic Kidney Disease, Autosomal Recessive"
220 "Polycystic Kidney Disease, Autosomal Dominant"
221 Medullary Cystic Kidney Disease/Nephronophthisis
222 Renal Dysplasia
223 Renal Tubular Dysgenesis
224 Ask-Upmark Kidney
Reproductive System
Congenital/Genetic/Hereditary
225 Accessory Breast Tissue
226 Vaginal Adenosis
227 Cryptorchidism
228 Testicular Regression Syndrome
229 Gonadal Dysgenesis
Inflammatory/Immune Dysfunction
230 Hidradenitis Suppurativa
231 Childhood Beh�et Disease
Trauma/Injury/Reactive
232 Adnexal (Ovarian) Torsion
233 Meconium Periorchitis
234 Testicular Torsion
Miscellaneous
235 Ovarian Cysts
Hematopoietic
Lymph Nodes
Reactive Lymphadenopathies
236 Reactive Follicular Hyperplasia
237 Reactive Paracortical Hyperplasia
238 Progressive Transformation of Germinal Centers
239 Hyaline Vascular Castleman Disease
240 Dermatopathic Lymphadenitis
241 Kimura Disease
242 Rosai-Dorfman Disease
Infectious Lymphadenopathies
243 Infectious Mononucleosis Lymphadenitis
244 Cat Scratch Lymphadenitis
245 Mycobacterial Infections
246 Chronic Granulomatous Lymphadenitis
247 Toxoplasma Lymphadenitis
Blood and Bone Marrow
Congenital/Genetic/Hereditary
248 Chediak-Higashi Syndrome
249 Congenital Amegakaryocytic Thrombocytopenia
250 Congenital Thrombotic Thrombocytopenia Purprua
251 Congenital Erythrocytosis
252 Diamond-Blackfan Anemia
253 Hereditary Spherocytosis
254 Hereditary Elliptocytosis
255 Fanconi Anemia
256 Pyruvate Kinase Deficiency
257 Shwachman-Diamond Syndrome
258 Severe Congenital Neutropenia and Cyclic Neutropenia
259 Sickle Cell Anemia
260 Hemophagocytic Lymphohistiocytosis
261 Thalassemia
Infectious
262 Infectious Mononucleosis Syndromes
263 Parvo B-19 Infection
Miscellaneous
264 Transient Erythroblastopenia of Childhood
Thymus
Trauma/Injury/Reactive
265 Acute Thymic Involution