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Palmar Hyperhidrosis - Pipeline Insight, 2024

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    Drug Pipelines

  • 40 Pages
  • April 2024
  • Region: Global
  • DelveInsight
  • ID: 5396945
UP TO OFF until Dec 31st 2024
This “Palmar Hyperhidrosis- Pipeline Insight, 2024,” report provides comprehensive insights about 3+ companies and 3+ pipeline drugs in Palmar Hyperhidrosis pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Geography Covered

  • Global coverage

Palmar Hyperhidrosis Understanding

Palmar Hyperhidrosis: Overview

Palmar hyperhidrosis, or excessive hand sweating, is a common condition affecting 1-3% of the population. It usually starts in childhood or adolescence. Sweaty hands can significantly affect a person socially and emotionally. Many factors can contribute to the condition, including genetic influences as well as physical and emotional stress. A family history is present in up to 30% of cases. Palmar hyperhidrosis affects both hands equally and can range from mild clammy hands to severe sweating. It stops when sleep. Sweaty hands can be associated with increased sweating in other parts of the body including underarms (axillary hyperhidrosis), face and scalp (craniofacial hyperhidrosis) and feet (plantar hyperhidrosis).The condition can be very distressing due to its impact on quality of life. The diagnosis is usually made based on a history of excessive sweating. No investigations are needed. Further investigations are considered when larger areas of the body are affected or if hyperhidrosis occurs during sleep. Palmar hyperhidrosis will often need ongoing and persistent treatment. However, some people may notice the amount of sweating decreases as they get older. There seems to be a genetic predisposition to PH, evidenced by family transmission through autosomal dominant genes. Symptoms are usually bilateral and symmetrical and there are no other associated conditions. Palms are cold, wet and present color that can ranges from pale to blush. The episode of sweating has abrupt onset, related or not with emotional stressful events, and presents more intensely on the palms and fingers and less intensely in the posterior regions of the hands. Rapidly, the hands are wet by the droplet detachment, and in some cases there may be swelling of the fingers. The PH diagnosis is eminently clinical, being conducted through history and physical examination.

Palmar Hyperhidrosis- Pipeline Insight, 2024 report outlays comprehensive insights of present scenario and growth prospects across the indication. A detailed picture of the Palmar Hyperhidrosis pipeline landscape is provided which includes the disease overview and Palmar Hyperhidrosis treatment guidelines. The assessment part of the report embraces, in depth Palmar Hyperhidrosis commercial assessment and clinical assessment of the pipeline products under development. In the report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, Palmar Hyperhidrosis collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Report Highlights

The companies and academics are working to assess challenges and seek opportunities that could influence Palmar Hyperhidrosis R&D. The therapies under development are focused on novel approaches to treat/improve Palmar Hyperhidrosis.

Palmar Hyperhidrosis Emerging Drugs Chapters

This segment of the Palmar Hyperhidrosis report encloses its detailed analysis of various drugs in different stages of clinical development, including phase II, I, preclinical and Discovery. It also helps to understand clinical trial details, expressive pharmacological action, agreements and collaborations, and the latest news and press releases.

Palmar Hyperhidrosis Emerging Drugs

AT-5214: Atacama Therapeutics AT-5214 (dexmecamylamine) is the S-enantiomer of mecamylamine, a selective inhibitor of the acetylcholine nicotinic receptor. AT-5214 is thought to inhibit the sympathetic ganglion with lessened parasympathetic side effects. Currently, it is in Phase II stage of development to treat Palmar Hyperhidrosis.

Umeclidinium: Glaxo SmithKlineUmeclidinium is a Muscarinic receptor antagonist developed by GlaxoSmithKline. It is in Phase II stage of development to treat PalmarHyperhidrosis.

Palmar Hyperhidrosis: Therapeutic Assessment

This segment of the report provides insights about the different Palmar Hyperhidrosis drugs segregated based on following parameters that define the scope of the report, such as:

Major Players in Palmar Hyperhidrosis

There are approx. 3+ key companies which are developing the therapies for Palmar Hyperhidrosis. The companies which have their Palmar Hyperhidrosis drug candidates in the most advanced stage, i.e. phase II include, Atacama Therapeutics.

Phases

This report covers around 3+ products under different phases of clinical development like
  • Late stage products (Phase III)
  • Mid-stage products (Phase II)
  • Early-stage product (Phase I) along with the details of
  • Pre-clinical and Discovery stage candidates
  • Discontinued & Inactive candidates

Route of Administration

Palmar Hyperhidrosis pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
  • Intra-articular
  • Intraocular
  • Intrathecal
  • Intravenous
  • Ophthalmic
  • Oral
  • Parenteral
  • Subcutaneous
  • Topical
  • Transdermal

Molecule Type

Products have been categorized under various Molecule types such as

  • Oligonucleotide
  • Peptide
  • Small molecule

Product Type

Drugs have been categorized under various product types like Mono, Combination and Mono/Combination.

Palmar Hyperhidrosis: Pipeline Development Activities

The report provides insights into different therapeutic candidates in phase II, I, preclinical and discovery stage. It also analyses Palmar Hyperhidrosis therapeutic drugs key players involved in developing key drugs.

Pipeline Development Activities

The report covers the detailed information of collaborations, acquisition and merger, licensing along with a thorough therapeutic assessment of emerging Palmar Hyperhidrosis drugs.

Palmar Hyperhidrosis Report Insights

  • Palmar Hyperhidrosis Pipeline Analysis
  • Therapeutic Assessment
  • Unmet Needs
  • Impact of Drugs

Palmar Hyperhidrosis Report Assessment

  • Pipeline Product Profiles
  • Therapeutic Assessment
  • Pipeline Assessment
  • Inactive drugs assessment
  • Unmet Needs

Key Questions

Current Treatment Scenario and Emerging Therapies:
  • How many companies are developing Palmar Hyperhidrosis drugs?
  • How many Palmar Hyperhidrosis drugs are developed by each company?
  • How many emerging drugs are in mid-stage, and late-stage of development for the treatment of Palmar Hyperhidrosis?
  • What are the key collaborations (Industry-Industry, Industry-Academia), Mergers and acquisitions, licensing activities related to the Palmar Hyperhidrosis therapeutics?
  • What are the recent trends, drug types and novel technologies developed to overcome the limitation of existing therapies?
  • What are the clinical studies going on for Palmar Hyperhidrosis and their status?
  • What are the key designations that have been granted to the emerging drugs?

Key Players

  • Atacama Therapeutics
  • GlaxoSmithKline
  • Brickell Biotech, Inc.
  • Candesant Biomedical

Key Products

  • AT-5214
  • Umeclidinium
  • Sofpironium bromide


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Table of Contents

IntroductionExecutive Summary
Palmar Hyperhidrosis: Overview
  • Causes
  • Mechanism of Action
  • Signs and Symptoms
  • Diagnosis
  • Disease Management
Pipeline Therapeutics
  • Comparative Analysis
Therapeutic Assessment
  • Assessment by Product Type
  • Assessment by Stage and Product Type
  • Assessment by Route of Administration
  • Assessment by Stage and Route of Administration
  • Assessment by Molecule Type
  • Assessment by Stage and Molecule Type
Palmar Hyperhidrosis- Analytical Perspective
Late Stage Products (Phase III)
  • Comparative Analysis
Drug Name:Company Name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Mid Stage Products (Phase II)
  • Comparative Analysis
AT-5214: Atacama Therapeutics
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Early Stage Products (Phase I)
  • Comparative Analysis
Drug Name : Company Name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Preclinical and Discovery Stage Products
  • Comparative Analysis
Drug Name: Company Name
  • Product Description
  • Research and Development
  • Product Development Activities
Drug profiles in the detailed report…..
Inactive Products
  • Comparative Analysis
Palmar Hyperhidrosis Key CompaniesPalmar Hyperhidrosis Key ProductsPalmar Hyperhidrosis- Unmet NeedsPalmar Hyperhidrosis- Market Drivers and BarriersPalmar Hyperhidrosis- Future Perspectives and ConclusionPalmar Hyperhidrosis Analyst ViewsPalmar Hyperhidrosis Key CompaniesAppendix
List of Tables
Table 1 Total Products for Palmar Hyperhidrosis
Table 2 Late Stage Products
Table 3 Mid Stage Products
Table 4 Early Stage Products
Table 5 Pre-clinical & Discovery Stage Products
Table 6 Assessment by Product Type
Table 7 Assessment by Stage and Product Type
Table 8 Assessment by Route of Administration
Table 9 Assessment by Stage and Route of Administration
Table 10 Assessment by Molecule Type
Table 11 Assessment by Stage and Molecule Type
Table 12 Inactive Products
List of Figures
Figure 1 Total Products for Palmar Hyperhidrosis
Figure 2 Late Stage Products
Figure 3 Mid Stage Products
Figure 4 Early Stage Products
Figure 5 Preclinical and Discovery Stage Products
Figure 6 Assessment by Product Type
Figure 7 Assessment by Stage and Product Type
Figure 8 Assessment by Route of Administration
Figure 9 Assessment by Stage and Route of Administration
Figure 10 Assessment by Molecule Type
Figure 11 Assessment by Stage and Molecule Type
Figure 12 Inactive Products

Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

  • Atacama Therapeutics
  • GlaxoSmithKline
  • Brickell Biotech, Inc.
  • Candesant Biomedical