Methodological Approaches for Sleep and Vigilance Research examines experimental procedures used to study the sleep-wake cycle, with topics covered by world leaders in the field. The book focuses on techniques commonly used in the sleep field, including polysomnography, electrophysiology, single- and multi-unit spiking activity recording, brain stimulation, EEG power spectra, optogenetics, telemetry, and wearable and non-wearable tracking devices. Further chapters on imaging techniques, questionnaires for sleep assessment, genome-wide association studies, artificial intelligence and big data are also featured. This discussion of significant conceptual advances into experimental procedures is suitable for anyone interested in the neurobiology of sleep.
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Table of Contents
1. Definitions and Measurements of the States of Vigilance2. Polysomnographic Procedures as an Approach for Studying the Sleep-Wake Cycle
3. Electrophysiology studies in the Sleep-Wake Cycle
4. Tracking Single- and Multi-Unit Activity through the Sleep-Wake Cycle
5. Brain deep stimulation for understanding the sleep-wake phenomena
6. EEG functional connectivity and EEG power spectra in sleep
7. Multi-site recordings: From single cell to circuit level dissection of Sleep-wake in mice
8. Optogenetics and Sleep Research
9. Behavioral States Monitored by Telemetry
10. Wearable and Non-Wearable Sleep-Tracking Devices
11. Clinical Trial: Imaging Techniques in Sleep Studies
12. Objective Questionnaires for Assessment Sleep Quality
13. Genome-Wide Association Studies of Sleep Phenotypes
14. Artificial Intelligence as a Clinical Psychoinformatic Approach for the Analysis of the Behavioral States
15. Big Data Providing Insights for Sleep Medicine