Chapter 1 Executive Summary
- Market Outlook
- Scope of Report
- Market Insights
Chapter 2 Market Overview
- Definitions
- History of Oligonucleotide Synthesis
- First Dinucleotide
- Solid Phase Synthesis
- Types of Oligonucleotides
- DNA Probes
- RNA Probes
- Oligonucleotide Synthesis Processes
- Solid Phase Chemical Synthesis
- Alternative Forms of Oligonucleotide Synthesis
- Versatile Functions of Synthetic Oligonucleotides
- Regulatory Paths for Oligotherapeutics
- Animal Models and Studies
- Role of Regulatory Authorities
Chapter 3 Market Dynamics
- Drivers
- Increasing Use of Synthesized Oligos in Therapeutic Applications
- Rising Government Investments for Synthetic Biology and Genome Projects
- Growing Focus on Personalized Medicine
- Restraints
- Complexities Associated with Oligos
- Lack of Clear Regulatory Infrastructure
- Opportunities
- Expansion of Companies
- Emerging Applications in Various Fields
Chapter 4 Emerging Technologies and Developments
- Overview
- DNA Synthesizers
- Emerging Technologies
- Microfluidics Approach
- Enzymatic De Novo DNA Synthesis
Chapter 5 Market Segmentation Analysis
- Segmentation Breakdown
- Global Market for Oligonucleotide Synthesis, by Product Type
- Oligonucleotide Drugs
- Equipment and Reagents
- Synthesized Oligos
- Services
- Global Market for Oligonucleotide Synthesis, by Application
- Research
- Diagnostics and Therapeutics
- Geographic Breakdown
- Global Market for Oligonucleotide Synthesis, by Region
- North America
- Europe
- Asia-Pacific
- Rest of the World
Chapter 6 Competitive Intelligence
- Competitive Landscape
- Patent Analysis
- M&A Analysis
- Funding Outlook
- Industry Structure
Chapter 7 ESG Development
- Introduction to ESG
- Assessing the Sustainability of the Oligonucleotide Manufacturing Process
- Assessment Against the 12 Principles of Green Chemistry
- Process Mass Intensity (PMI) Assessment
- Assessment of Compounds Used in Oligonucleotide Manufacture
- ESG Performance in Market
- Concluding Remarks
List of Tables
Summary Table: Global Market for Oligonucleotides, by Region, Through 2028
Table 1: History of Oligonucleotide Therapeutics, 1964-2013
Table 2: Comparison of Oligonucleotide and Polynucleotide
Table 3: Yield, Length and Coupling Efficiency of Oligonucleotide
Table 4: List of Approved Oligonucleotide Therapeutics, 2023
Table 5: Global Market for Oligonucleotide Synthesis, by Product Type, Through 2028
Table 6: Global Market for Oligonucleotide Drugs, by Region, Through 2028
Table 7: Revenue Generated, by Few Oligonucleotide Drugs, 2022
Table 8: Global Market for Equipment and Reagents, by Region, Through 2028
Table 9: Global Market for Synthesized Oligos, by Region, Through 2028
Table 10: Pricing of Oligo Pools, by Twist Bioscience
Table 11: Pricing for Oligo pools, by GenScript
Table 12: Global Market for Services, by Region, Through 2028
Table 13: Global Market for Oligonucleotide Synthesis, by Application, Through 2028
Table 14: Global Market for Research Applications, by Region, Through 2028
Table 15: Global Market for Diagnostic and Therapeutic Applications, by Region, Through 2028
Table 16: Global Market for Oligonucleotide Synthesis, by Region, Through 2028
Table 17: North American Market for Oligonucleotide Synthesis, by Product Type, Through 2028
Table 18: North American Market for Oligonucleotide Synthesis, by Application, Through 2028
Table 19: North American Market for Oligonucleotide Synthesis, by Country, Through 2028
Table 20: European Market for Oligonucleotide Synthesis, by Product Type, Through 2028
Table 21: European Market for Oligonucleotide Synthesis, by Application, Through 2028
Table 22: European Market for Oligonucleotide Synthesis, by Country, Through 2028
Table 23: Asia-Pacific Market for Oligonucleotide Synthesis, by Product Type, Through 2028
Table 24: Asia-Pacific Market for Oligonucleotide Synthesis, by Application, Through 2028
Table 25: Asia-Pacific Market for Oligonucleotide Synthesis, by Country, Through 2028
Table 26: RoW Market for Oligonucleotide Synthesis, by Product Type, Through 2028
Table 27: RoW Market for Oligonucleotide Synthesis, by Application, Through 2028
Table 28: Top Oligonucleotide Synthesis Manufacturers, 2022
Table 29: Select Patents on Oligonucleotide Synthesis Published in 2020
Table 30: Select Patents on Oligonucleotide Synthesis Published in 2021
Table 31: Select Patents on Oligonucleotide Synthesis Published in 2022
Table 32: Select Patents on Oligonucleotide Synthesis Published in 2023
Table 33: Major Strategic Alliances in Oligonucleotide Synthesis Industry, 2023
Table 34: Top Deals in Oligonucleotide Synthesis Industry, 2023
Table 35: Antisense Oligonucleotides Cancer Therapeutics in Clinical Trials
Table 36: siRNA Cancer Therapeutics in Clinal Trials
Table 37: miRNA Cancer Therapeutics in Clinal Trials
Table 38: Assessment of the Oligonucleotide Manufacturing Process Against the 12 Principles of Green Chemistry
Table 39: Assessment of Compounds Used in Oligonucleotide Manufacture against the CHEM21 Solvent Guide
Table 40: Key Focus Areas in ESG Metrics
Table 41: ESG Rankings for Oligonucleotide Companies, 2023*
Table 42: Acronyms Used in this Report
Table 43: Agilent Technologies Inc.: Company Snapshot
Table 44: Agilent Technologies Inc.: Financial Performance, F.Y. 2022 and 2023
Table 45: Agilent Technologies Inc.: Product Portfolio
Table 46: Agilent Technologies Inc.: News/Key Developments, 2022-2023
Table 47: Biolegio B.V.: Company Snapshot
Table 48: Biolegio B.V.: Product Portfolio
Table 49: Biolytic Lab Performance Inc.: Company Snapshot
Table 50: Biolytic Lab Performance Inc.: Product Portfolio
Table 51: Biolytic Lab Performance Inc.: News/Key Developments, 2021
Table 52: Eurofins Scientific: Company Snapshot
Table 53: Eurofins Scientific: Financial Performance, FY 2022 and 2023
Table 54: Eurofins Scientific: Product Portfolio
Table 55: GenScript: Company Snapshot
Table 56: GenScript: Financial Performance, FY 2021 and 2022
Table 57: GenScript: Product Portfolio
Table 58: GenScript: News/Key Developments, 2021-2023
Table 59: Integrated DNA Technologies Inc.: Company Snapshot
Table 60: Integrated DNA Technologies Inc.: Product Portfolio
Table 61: Integrated DNA Technologies Inc.: News/Key Developments, 2021-2023
Table 62: L.C. Sciences: Company Snapshot
Table 63: L.C. Sciences: Product Portfolio
Table 64: LGC Group: Company Snapshot
Table 65: LGC Group: Financial Performance, FY 2022 and 2023
Table 66: LGC Group: Product Portfolio
Table 67: LGC Group: News/Key Developments, 2023
Table 68: Merck KGaA: Company Snapshot
Table 69: Merck KGaA: Financial Performance, FY 2022 and 2023
Table 70: Merck KGaA: Product Portfolio
Table 71: Merck KGaA: News/Key Developments, 2021
Table 72: Microsynth AG: Company Snapshot
Table 73: Microsynth AG: Product Portfolio
Table 74: Microsynth AG: News/Key Developments, 2021-2023
Table 75: Thermo Fisher Scientific Inc.: Company Snapshot
Table 76: Thermo Fisher Scientific Inc.: Financial Performance, FY 2022 and 2023
Table 77: Thermo Fisher Scientific Inc.: Product Portfolio
Table 78: Thermo Fisher Scientific Inc.: News/Key Developments, 2021-2023
List of Figures
Summary Figure: Global Market Shares of Oligonucleotides, by Region, 2022
Figure 1: History of the Solid-Phase Synthesis of Oligonucleotide
Figure 2: Summary of Solid-Phase Oligonucleotide Synthesis Cycle
Figure 3: Classification of Synthetic Oligonucleotides
Figure 4: Dynamics of the Global Market for Oligonucleotides
Figure 5: Global Market Shares of Oligonucleotide Synthesis, by Product Type, 2022
Figure 6: Global Market for Oligonucleotide Drugs, 2020-2028
Figure 7: Global Market for Oligonucleotide Drugs, by Region, 2020-2028
Figure 8: Global Market for Equipment and Reagents, 2020-2028
Figure 9: Global Market for Equipment and Reagents, by Region, 2020-2028
Figure 10: Global Market for Synthesized Oligos, 2020-2028
Figure 11: Global Market for Synthesized Oligos, by Region, 2020-2028
Figure 12: Global Market for Services, 2020-2028
Figure 13: Global Market for Services, by Region, 2020-2028
Figure 14: Global Market Shares of Oligonucleotide Synthesis, by Application, 2022
Figure 15: Global Market for Research Applications, 2020-2028
Figure 16: Global Market for Research Applications, by Region, 2020-2028
Figure 17: Global Market for Diagnostic and Therapeutic Applications, 2020-2028
Figure 18: Global Market for Diagnostics and Therapeutics, by Region, 2020-2028
Figure 19: Global Market for Oligonucleotide Synthesis, by Region, 2020-2028
Figure 20: North American Market Shares of Oligonucleotide Synthesis, by Product Type, 2022
Figure 21: North American Market Shares of Oligonucleotide Synthesis, by Application, 2020
Figure 22: North American Market Shares of Oligonucleotide Synthesis, by Country, 2022
Figure 23: European Market Shares of Oligonucleotide Synthesis, by Product Type, 2022
Figure 24: European Market Shares of Oligonucleotide Synthesis, by Application, 2022
Figure 25: European Market Shares of Oligonucleotide Synthesis, by Country, 2022
Figure 26: Asia-Pacific Market Shares of Oligonucleotide Synthesis, by Product Type, 2022
Figure 27: Asia-Pacific Market Shares of Oligonucleotide Synthesis, by Application, 2022
Figure 28: Asia-Pacific Market Shares of Oligonucleotide Synthesis, by Country, 2022
Figure 29: RoW Market Shares of Oligonucleotide Synthesis, by Product Type, 2022
Figure 30: RoW Market Shares of Oligonucleotide Synthesis, by Application, 2022
Figure 31: Drug Manufacturer Shares of Oligonucleotides, 2022
Figure 32: Patent Applications and Patents Granted, 2000-2023
Figure 33: Venture Capital Deals Including Corporate Pharma and Biotech Investors, by Year, 2010-2023
Figure 34: How a Strong ESG Proposition Benefits Businesses
Figure 35: ESG Adoption Level across Industries
Figure 36: Agilent Technologies Inc.: Revenue Share, by Business Unit, FY 2023
Figure 37: Agilent Technologies Inc.: Revenue Share, by Country/Region, FY 2023
Figure 38: Eurofins Scientific: Revenue Share, by Country/Region, FY 2023
Figure 39: GenScript: Revenue Share, by Business Unit, FY 2022
Figure 40: GenScript: Revenue Share, by Country/Region, FY 2022
Figure 41: LGC Group: Revenue Shares, by Business Unit, F.Y. 2023
Figure 42: LGC Group: Revenue Share, by Country/Region, FY 2023
Figure 43: Merck KGaA: Revenue Share, Business Unit, FY 2023
Figure 44: Merck KGaA: Revenue Share, by Country/Region, FY 2023
Figure 45: Thermo Fisher Scientific Inc.: Revenue Share, by Business Unit, FY 2023
Figure 46: Thermo Fisher Scientific Inc.: Revenue Share, by Country/Region, FY 2023
