Whole Genome and Exome Sequencing Market: By Application, Organism and Product with Executive and Consultant Guides

1.1 Whole Genome Sequencing Market - Strategic Situation Analysis
1.2 Guide for Executives, Marketing, Sales and Business Development Staff
1.3 Guide for Management Consultants and Investment Advisors

2.1 Whole Genome Sequencing Definition In This Report
2.1.1 Whole and Exome Sequencing
2.1.2 Research
2.1.3 Clinical Human
2.1.4 Clinical Human Rapid
2.1.5 Clinical Tumor
2.1.6 Clinical Pathogen
2.1.7 Agri/Other
2.1.8 Direct to Consumer
2.2 The Genomics Revolution
2.3 Market Definition
2.3.1 Revenue Market Size
2.4 Methodology
2.4.1 Methodology
2.4.2 Sources
2.4.3 Authors
2.5 Perspective: Healthcare and the IVD Industry
2.5.1 Global Healthcare Spending
2.5.2 Spending on Diagnostics
2.5.3 Important Role of Insurance for Diagnostics
2.6 Sizing the Genome - Not What You Think
2.6.1 Cost, Price and Genome Size, Pricing Practice
2.7 GLOBAL LISTING OF HIGH THROUGHPUT SEQUENCING ESTABLISHMENTS INSTALLED

3.1 Market Participants Play Different Roles
3.1.1 Instrument Manufacturer
3.1.2 Independent lab specialized/esoteric
3.1.3 Independent lab national/regional
3.1.4 Independent lab analytical
3.1.5 Public National/regional lab
3.1.6 Hospital lab
3.1.7 Physician lab
3.1.8 DTC Lab
3.1.9 Sequencing Labs
3.1.10 Audit body
3.2 Whole Genome Sequencing -Markets, Examples and Discussion
3.2.1 Direct to Consumer - Two Approaches
3.2.1.1 The New Age of Medical Information
3.2.1.2 Dangers in DTC-WGS - Health Costs and Regulation
3.2.1.3 Newborn and Prenatal - A Brave New World
3.2.1.4 DTC - How Many Segments?
3.2.2 Research Markets
3.2.2.1 Research Funding and Capital Expense
3.2.2.2 WGS Datasets Preferred
3.2.2.3 Existing research repurposed
3.2.2.4 Organism Wide Market
3.2.2.5 Service Suppliers Respond
3.2.3 Clinical - Understanding Germline and Somatic
3.2.3.1 Somatic - Chasing Mutations and Pharmacogenomics
3.2.4 Pathogen Testing
3.2.4.1 The Hepatitis C Story
3.2.4.2 Will the Microbiology Department Disappear?
3.2.5 AgriBio - Big Business
3.2.5.1 GMO is Here to Stay
3.2.5.2 WGS Benefits and Risks
3.2.5.3 The New Agriculture
3.3 Industry Structure
3.3.1 Hospital’s Testing Share
3.3.2 Economies of Scale
3.3.3 Instrument Manufacturer Role
3.3.4 Healthcare Industry Impacts - Still Struggling
3.3.4.1 Can the Healthcare Industry Adapt?
3.3.4.2 Genetic Counselling as an Industry
3.3.4.3 WGES Adoption and Cannibalization
3.3.4.4 The Meaning of Grail

4.1 Factors Driving Growth
4.1.1 Diagnostic Factors
4.1.2 Interpreting the Code Otherwise
4.1.3 Changes in Agriculture
4.1.4 Fertility Technology Comes of Age
4.1.5 Pathogen Challenges
4.2 Factors Limiting Growth
4.2.1 Increased Competition Lowers Price
4.2.2 Lower Costs
4.2.3 Healthcare Cost Concerns Curtail Growth
4.2.4 Wellness has a downside
4.2.5 GMO Opposition Movement
4.3 Sequencing Instrumentation
4.3.1 Instrumentation Tenacity
4.3.2 Declining Cost Changes Industry Structure
4.3.3 LISTING of CURRENT NGS INSTRUMENT SPECIFICATIONS
4.3.4 Illumina
4.3.5 ION
4.3.6 Pacific Biosystems
4.3.7 Roche 454
4.3.8 SOLiD
4.3.9 Oxford Nanopore
4.3.9.1 What is Oxford Nanopore Sequencing?
4.3.9.2 What can Oxford Nanopore Sequencing be used for?
4.3.9.3 Oxford Nanopore Products
4.3.10 Long Reads - Further Segmentation
4.3.11 Linked Reads
4.3.12 Targeted Sequencing Adopts CRISPR
4.3.13 New Sequencing Technologies
4.3.13.1 RNAP sequencing
4.3.13.2 In vitro virus high-throughput sequencing
4.3.13.3 Tunnelling currents DNA sequencing
4.3.13.4 Sequencing by hybridization
4.3.13.5 Sequencing with mass spectrometry
4.3.13.6 Microfluidic Sanger sequencing
4.3.13.7 Microscopy-based techniques

5.1 Recent Developments - Importance and How to Use This Section
5.1.1 Importance of These Developments
5.1.2 How to Use This Section
5.2 Epic, GeneDx to broaden WGS potential
5.3 Qiagen QiaSeq xHyb Mycobacterium Tuberculosis Panel
5.4 WGS Uncovers Genetic causes of cerebral palsy
5.5 Rapid WGS Use Recommended for Intensive Care
5.6 Quest and Ultima Genomics to Develop Tests
5.7 WHO Launches WGS Guide
5.8 Myriad Genetics to Study MRD Testing
5.9 Adela Developing Epigenetic Multi-Cancer Detection
5.10 Epic Sciences Expanding Infrastructure for Liquid Biopsy Test
5.11 Bionano Laboratories Announces New Prenatal Whole Genome Tests
5.12 Myriad Genetics Plans Product Launches
5.13 Genomics England, Aims to Sequence 100K Newborns
5.14 Juno Diagnostics NIPT With At-Home Sample Collection
5.15 Cardio Diagnostics Launches Genetic Cardio Risk Test
5.16 Universal Genetic Testing in Breast Cancer Further Supported
5.17 Aniling Gets CE-IVD Marks for Cancer Sequencing Tests
5.18 MyOme Lands Investment for WGS
5.19 GenomSys Gains CE Mark for New Genomic Analysis Software
5.20 WGS Finds Lung Cancers Fall Into Molecular Subtypes
5.21 Testing Distinguishes Benign Tumors From Precancerous Condition
5.22 Plan to Sequence All Newborns in UK
5.23 Clear Labs Raises $60M for Nanopore Sequencing
5.24 Variantyx Expands Into Prenatal, Cancer Testing
5.25 Whole-Genome Sequencing Aids Diagnosis in Stockholm
5.26 Variantyx Raises $20M
5.27 Nonacus WGS Service for SARS-CoV-2 Laboratories
5.28 Center to Report Risk Scores in Clinical WGS
5.29 Stanford Launches WGS for Cardiovascular Testing
5.30 Illumina and NY Healthcare Partner on Clinical WGS
5.31 Increased Adoption of WGS Needs Acceptance by Payors, Providers
5.32 Veritas Intercontinental Completes €5M Series B Financing Round
5.33 M2GEN and Discovery Life Sciences in Bioinformatics Agreement
5.34 Genomics England Adopts Quantum ActiveScale Object Storage
5.35 GenomiQa, Icon Group to Validate Genomic Analysis Platform CapeDx
5.36 NHS Wales Introduces WGS for Critically Ill Newborns
5.37 Illumina Achieves EAU for NGS-Based SARS-CoV-2 Test
5.38 C2i Genomics to Launch Trials for MRD Detection Tech
5.39 Roche Acquires Sequencing Company Stratos Genomics
5.40 UK COVID-19 Sequencing Consortium Launches
5.41 Invitae Acquires Three Companies: YouScript, Genelex, Diploid
5.42 Experience From Centralized Genomic Medicine Lab
5.43 MGI to Enable $100 Human Genome
5.44 Nebula Genomics offers $299 WGS
5.45 Team to Study Campylobacter Omics
5.46 Veritas Genetics Restarts US Business
5.47 NEOGEN, Gencove partner to advance animal genomics

6.1 10x Genomics, Inc.
6.2 1928 Diagnostics
6.3 23andME Inc.
6.4 Abbott Laboratories
6.5 AccuraGen Inc.
6.6 Adaptive Biotechnologies
6.7 Admera Health, LLC
6.8 Agilent/Dako
6.9 Akonni Biosystems
6.10 Amoy Diagnostics Co., Ltd.
6.11 Ancestry.com LLC
6.12 Anchor Dx
6.13 ARUP Laboratories
6.14 BaseClear
6.15 Baylor Miraca Genetics Laboratories
6.16 Beckman Coulter Diagnostics
6.17 Becton, Dickinson and Company
6.18 BGI Genomics Co. Ltd
6.19 Bioarray Genetics
6.20 Biocept, Inc.
6.21 Biodesix Inc.
6.22 BioFluidica
6.23 BioGenex
6.24 Biolidics Ltd
6.25 bioMérieux Diagnostics
6.26 Bioneer Corporation
6.27 Bio-Rad Laboratories, Inc
6.28 Bio-Techne
6.29 C2i Genomics
6.30 Caris Molecular Diagnostics
6.31 CellMax Life
6.32 Centogene
6.33 Circulogene
6.34 Clear Labs
6.35 Clinical Genomics
6.36 Complete Genomics, Inc. - A BGI Company
6.37 CosmosID
6.38 Dante Labs
6.39 Datar Cancer Genetics Limited
6.40 Day Zero Diagnostics.
6.41 Diasorin S.p.A.
6.42 Element Biosciences
6.43 Element Biosciences
6.44 Epic Sciences
6.45 Epigenomics AG
6.46 Eurofins Scientific
6.47 Excellerate Bioscience
6.48 Fabric Genomics
6.49 Freenome
6.50 FUJIFILM Wako Diagnostics
6.51 Fulgent Genetics
6.52 GE Global Research
6.53 Gencove
6.54 Genedrive
6.55 GeneDx Holdings
6.56 GeneFirst Ltd.
6.57 Genetron Holdings
6.58 Genewiz
6.59 Genomics England
6.60 Genomics Personalized Health (GPH)
6.61 GenomOncology
6.62 Genzyme Corporation
6.63 Grifols
6.64 Guardant Health
6.65 Guardiome
6.66 HeiScreen
6.67 Helix
6.68 Helix OpCo
6.69 Helomics
6.70 Hologic
6.71 HTG Molecular Diagnostics
6.72 Human Longevity, Inc.
6.73 iCellate
6.74 Illumina
6.75 Incell Dx
6.76 Inivata
6.77 Invitae Corporation
6.78 Invivoscribe
6.79 Karius
6.80 Lunglife AI Inc
6.81 Macrogen
6.82 MDNA Life SCIENCES, Inc.
6.83 MDx Health
6.84 Medgenome
6.85 Meridian Bioscience
6.86 Mesa Biotech (Thermo Fisher)
6.87 Mesa Laboratories, Inc.
6.88 miR Scientific
6.89 MNG Labs
6.90 NantHealth, Inc.
6.91 Natera
6.92 Nebula Genomics
6.93 NeoGenomics
6.94 New England Biolabs, Inc.
6.95 Novogene Bioinformatics Technology Co., Ltd.
6.96 Omega Bioservices
6.97 Oncocyte
6.98 OncoDNA
6.99 OpGen
6.100 ORIG3N, Inc.
6.101 Origene Technologies
6.102 Oxford Nanopore Technologies
6.103 Pacific Biosciences
6.104 Panagene
6.105 Pathogenomix
6.106 PathoQuest S.A.
6.107 Personal Genome Diagnostics
6.108 Personalis
6.109 Precipio
6.110 PrecisionMed
6.111 Promega
6.112 Protagen Diagnostics
6.113 Qiagen
6.114 QuantuMDx
6.115 Regeneron Pharmaceuticals
6.116 Revvity
6.117 Roche Molecular Diagnostics
6.118 Roswell Biotechnologies
6.119 Seegene
6.120 Sequencing.com
6.121 Siemens Healthineers
6.122 simfo GmbH
6.123 Singlera Genomics Inc.
6.124 Singular Genomics
6.125 SkylineDx
6.126 Standard BioTools
6.127 Sure Genomics, Inc.
6.128 Sysmex
6.129 Sysmex Inostics
6.130 Tempus Labs, Inc.
6.131 Thermo Fisher Scientific Inc.
6.132 Ultima Genomics
6.133 Ultima Genomics
6.134 Variantyx
6.135 Volition
6.136 Vyant Bio
6.137 Zymo Research Corp

7.1 Global Market Overview by Country
7.1.1 Table - Global Market by Country
7.1.2 Chart - Global Market by Country
7.2 Global Market by Application - Overview
7.2.1 Table - Global Market by Application
7.2.2 Chart - Global Market by Application - Base/Final Year Comparison
7.2.3 Chart - Global Market by Application - Base Year
7.2.4 Chart - Global Market by Application - Final Year
7.2.5 Chart - Global Market by Application - Share by Year
7.2.6 Chart - Global Market by Application - Segment Growth
7.3 Global Market by Organism - Overview
7.3.1 Table - Global Market by Organism
7.3.2 Chart - Global Market by Organism - Base/Final Year Comparison
7.3.3 Chart - Global Market by Organism - Base Year
7.3.4 Chart - Global Market by Organism - Final Year
7.3.5 Chart - Global Market by Organism - Share by Year
7.3.6 Chart - Global Market by Organism - Segment Growth
7.4 Global Market by Product - Overview
7.4.1 Table - Global Market by Product
7.4.2 Chart - Global Market by Product - Base/Final Year Comparison
7.4.3 Chart - Global Market by Product - Base Year
7.4.4 Chart - Global Market by Product - Final Year
7.4.5 Chart - Global Market by Product - Share by Year
7.4.6 Chart - Global Market by Product - Segment Growth

8.1 Research
8.1.1 Table Research - by Country
8.1.2 Chart - Research Growth
8.2 Clinical Human
8.2.1 Table Clinical Human - by Country
8.2.2 Chart - Clinical Human Growth
8.3 Clinical Human Rapid
8.3.1 Table Clinical Human Rapid - by Country
8.3.2 Chart - Clinical Human Rapid Growth
8.4 Clinical Tumor
8.4.1 Table Clinical Tumor - by Country
8.4.2 Chart - Clinical Tumor Growth
8.5 Clinical Pathogen
8.5.1 Table Clinical Pathogen - by Country
8.5.2 Chart - Clinical Pathogen Growth
8.6 Direct to Consumer
8.6.1 Table Direct to Consumer - by Country
8.6.2 Chart - Direct to Consumer Growth
8.7 Agriculture/Other
8.7.1 Table Agriculture/Other - by Country
8.7.2 Chart - Agriculture/Other Growth

9.1 Human
9.1.1 Table Human - by Country
9.1.2 Chart - Human Growth
9.2 Pathogen
9.2.1 Table Pathogen - by Country
9.2.2 Chart - Pathogen Growth
9.3 Other Organism
9.3.1 Table Other Organism - by Country
9.3.2 Chart - Other Organism Growth

10.1 Instruments
10.1.1 Table Instruments - by Country
10.1.2 Chart - Instruments Growth
10.2 Reagents
10.2.1 Table Reagents - by Country
10.2.2 Chart - Reagent Growth
10.3 Analysis
10.3.1 Table Analysis - by Country
10.3.2 Chart - Analysis Growth
10.4 Software & Other
10.4.1 Table Software & Other - by Country
10.4.2 Chart - Software & Other Growth

12.1 United States Medicare System: Laboratory Fees Schedule
12.2 The Most Used IVD Assays
12.3 The Highest Grossing Assays
12.4 The Whole Genome Sequence of SARS-CoV-2

Table 1 The Base Pairs
Table 2 Most Common Traditional Genetic Disorders
Table 3 List of GLOBAL SEQUENCING LOCATIONS
Table 4 Market Players by Type
Table 5 The Different Markets for Whole Genome Sequencing
Table 6 DTC Sub Segments
Table 7 Roles of WGS in AgriBio
Table 8 The Factors Driving Growth
Table 9 Factors Limiting Growth
Table 10 - Listing of Current NGS Instrument Specifications
Table 11 Six New Sequencing Technologies
Table 12 - Global Market by Region
Table 13 Global Market by Application
Table 14 Global Market by Organism
Table 15 Global Market by Product
Table 16 Research by Country
Table 17 Clinical Human by Country
Table 18 Clinical Human Rapid by Country
Table 19 Clinical Tumor by Country
Table 20 Clinical Pathogen by Country
Table 21 Direct to Consumer by Country
Table 22 Agriculture/Other by Country
Table 23 Human by Country
Table 24 Pathogen by Country
Table 25 Other Organism by Country
Table 26 Instruments by Country
Table 27 Reagents by Country
Table 28 Analysis by Country
Table 29 Software & Other by Country
Table 30 Clinical Lab Fee Schedule
Table 31 The Most Common Assays
Table 32 Largest Revenue Assays