Advances in Non-coding RNAs in Cancer-Biology and Immunology covers the machinery of non-coding RNAs, including microRNA, LnRNA and piRNA, the identification of targets of these non-coding RNAs, and the identification of physiological and pathological roles of miRNAs, LnRNAs and piRNAs in immunology and cancer biology. The book introduces basic ideas of miRNAs, LnRNAs and piRNAs, along with detailed bio-processing steps, critical functions in the development of tumorigenesis and controlling immune cell responses, benefits for identifying different classes of non-coding RNAs and their targets, and finally, tactics on how to identify new members of these non-coding RNAs and predict possible functions.
In addition, the book captures the essence of the pioneering work of some of the world's leading researchers, showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs, LnRNAs and piRNAs, while also highlighting their potential towards the diagnosis and therapeutics of various diseases.
Table of Contents
1. The Machinery for MicroRNAs, LnRNAs and piRNAs2. MicroRNAs in cancer research
3. MicroRNAs in immunity
4. Advances of LnRNAs in cancer research
5. Advances of LnRNAs in immunity
6. Current view of piRNAs in cancer studies
7. Current view of piRNAs in immunity
8. MicroRNAs in diagnosis and therapeutics
9. LnRNAs as a tool for personalized therapy in cancers and immune-related diseases
10. piRNAs in the pathophysiology of disease and potential clinical applications
Authors
Shuai Jiang Associate Professor, Louisiana State University Health Sciences Center Shreveport, USA. Immunologist and cancer biologist with 10+ years of research experience using tissue culture and engineered mouse models. Experienced in experimentation, supervision of research associates, manuscript preparation, and scientific presentation. First author of peer-reviewed manuscripts and book chapter author, with experience as a journal guest editor and manuscript peer reviewer. Louisiana State University Health Sciences Center Shreveport, Assistant Professor (2019-present)California Institute of Technology, Post-Doctoral Fellow (Advisor: David Baltimore, Ph.D.); 2012-2019 . Investigated the physiological roles of microRNA let-7 clusters in macrophage inflammatory responses through the regulation of cellular metabolism
. Researched the physiological roles of microRNA let-7 clusters in B-cell antibody production through the regulation of cellular metabolism
