Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides.
Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development.
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Table of Contents
1. Historical developments of antimicrobial peptide research2. Biosynthesis of peptide antibiotics and innate immunity
3. Antimicrobial peptides: features and mode of action
4. Purification techniques and characterisation of antimicrobial peptides
5. Peptide antibiotics from bacteria
6. Antimicrobial peptides of fungal origin
7. Insect peptides with antimicrobial effect
8. Amphibian host defence peptides
9. Plant derived antimicrobial peptides
10. Mammalian antimicrobial peptides
11. Antimicrobial peptides from marine environment
12. Peptides with antiviral activities
13. Peptide antibiotics against MDR bacteria
14. Antimicrobial peptide resistance
15. Recent advances and challenges in peptide drug development
16. Future perspective of peptide antibiotic market
