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Dermatomyositis - Epidemiology Forecast - 2032

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    Report

  • 112 Pages
  • September 2023
  • Region: Global
  • DelveInsight
  • ID: 5525737
UP TO OFF until Dec 31st 2024
This ‘Dermatomyositis - Epidemiology Forecast - 2032' report delivers an in-depth understanding of Dermatomyositis, historical and forecasted epidemiology, as well as the trends in the United States, EU4 (Germany, France, Italy, and Spain), and the United Kingdom, and Japan.

Dermatomyositis Understanding
Idiopathic inflammatory myopathies (IIM) are a heterogeneous group of connective tissue disorders characterized by progressive muscle weakness. IIM is the umbrella term that includes Dermatomyositis, polymyositis (PM), overlap myositis (OM), sporadic inclusion body myositis (IBM), and necrotizing autoimmune myopathy (NAM), also known as immune-mediated necrotizing myopathy (IMNM).

Dermatomyositis is a rare autoimmune disorder characterized by muscle inflammation (myositis) and skin inflammation (dermatitis). Proximal muscle weakness is a hallmark feature, affecting muscles close to the trunk, such as those in the thighs and upper arms, including heliotrope rash (purplish discoloration around the eyes), Gottron's papules (reddish bumps on knuckles), and photosensitive rash on sun-exposed areas.

Furthermore, Dermatomyositis is a complex and heterogeneous condition that occurs in adults and even children, juvenile Dermatomyositis (JDM). They share the hallmark features of pathognomic skin rash and muscle inflammation but are heterogeneous disorders with various additional features and complications.

Dermatomyositis Diagnosis

The diagnosis of Dermatomyositis involves a combination of clinical evaluation, detection of characteristic physical findings, certain laboratory tests, and imaging studies. Key diagnostic criteria include muscle weakness, characteristic skin rash, elevated muscle enzymes, myositis-associated enzyme levels, electromyography, and muscle biopsy. Muscle biopsy is the most accurate test to confirm the diagnosis and to exclude other causes of muscle weakness or skin rash. However, choosing the right muscle for a biopsy is crucial to prevent a missing diagnosis. Further, the differential diagnosis includes body myositis, myasthenia gravis, muscular dystrophies, motor neuron disease, neuropathy, and inherited metabolic myopathy.

Continued in the report…..

Dermatomyositis Epidemiology Perspective

The disease epidemiology covered in the report provides historical as well as forecasted epidemiology segmented by total diagnosed prevalent cases of Dermatomyositis, age-specific diagnosed prevalent cases of Dermatomyositis, gender-specific diagnosed prevalent cases of Dermatomyositis, severity-specific diagnosed prevalent cases of Dermatomyositis, chronicity-specific diagnosed prevalent cases of Dermatomyositis, and comorbidity-specific diagnosed prevalent cases of Dermatomyositis in the 7MM covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan from 2019 to 2032.

Dermatomyositis Detailed Epidemiology Segmentation
  • According to the publisher's estimates, in 2022, there were nearly 71,351 total diagnosed prevalent cases of Dermatomyositis in the 7MM, of which nearly 9% were juvenile and 91% were adult. These cases are expected to increase by 2032 during the study period (2019-2032).
  • Among the 7MM, the US accounted for approximately 54%, EU4 and the UK for nearly 29%, and Japan for 17% of the total diagnosed prevalent cases of Dermatomyositis in 2022. These cases are expected to increase by 2032.
  • In the US, the highest cases were found in the 40-59 age group, followed by the 60-79, 18-39, and 0-17 age groups, while the least cases were for the =80 age group, with nearly 14,524, 12,933, 5,203, 4,117, and 1,489 respectively in 2022. The cases are expected to increase during the study period.
  • In 2022, the US accounted for nearly 26,051 female and 12,215 male cases of Dermatomyositis. These cases will change during the study period (2019-2032).
  • As per the analysis, there were approximately 2,553 mild and 2,015 moderate to severe diagnosed prevalent cases of Dermatomyositis in the UK in 2022. These cases are subject to change and will increase by 2032.
  • According to the publisher's estimates, in 2022, among the total diagnosed prevalent cases of Dermatomyositis in the US, there were nearly 11,480 and 26,786 acute and chronic cases, projected to increase during the study period.
  • In Japan, comorbidities-specific diagnosed prevalent cases, including ILD, CVD, cancer malignancy, and others (osteoporosis, dysphagia, Raynaud's syndrome, calcinosis, etc.) accounted for nearly 2,462, 2,206, 511, and 7,269 diagnosed prevalent cases, respectively, in 2022. These cases are expected to change during the study period.

Scope of the Report

  • The report covers a descriptive overview of Dermatomyositis, explaining its symptoms, pathophysiology, and various diagnostic approaches.
  • The report provides insight into the 7MM historical and forecasted patient pool covering the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.
  • The report assesses the disease risk and burden of Dermatomyositis.
  • The report helps recognize the growth opportunities in the 7MM concerning the patient population.
  • The report provides the segmentation of the disease epidemiology for the 7MM, the total diagnosed prevalent cases of Dermatomyositis, age-specific diagnosed prevalent cases of Dermatomyositis, gender-specific diagnosed prevalent cases of Dermatomyositis, severity-specific diagnosed prevalent cases of Dermatomyositis, chronicity-specific diagnosed prevalent cases of Dermatomyositis, and comorbidity-specific diagnosed prevalent cases of Dermatomyositis.

Report Highlights

  • Ten years forecast of Dermatomyositis
  • The 7MM Coverage
  • Total diagnosed prevalent cases of Dermatomyositis
  • Age-specific diagnosed prevalent cases of Dermatomyositis
  • Gender-specific diagnosed prevalent cases of Dermatomyositis
  • Severity-specific diagnosed prevalent cases of Dermatomyositis
  • Chronicity-specific diagnosed prevalent cases of Dermatomyositis
  • Comorbidity-specific diagnosed prevalent cases of Dermatomyositis
Key Questions Answered
  • What are the disease risks and burdens of Dermatomyositis?
  • What is the historical dermatomyositis patient pool in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan?
  • What would be the forecasted patient pool of Dermatomyositis at the 7MM level?
  • What growth opportunities will be across the 7MM concerning the patient population with Dermatomyositis?
  • Which country would have the highest diagnosed prevalent population of Dermatomyositis among the countries mentioned above during the forecast period (2023-2032)?
  • At what CAGR is the population expected to grow across the 7MM forecast period (2023-2032)?

Reasons to Buy

The dermatomyositis report will allow the user to:
  • Develop business strategies by understanding the trends shaping and driving the 7MM dermatomyositis epidemiology forecast.
  • The dermatomyositis epidemiology report and model were written and developed by Masters and PhD level epidemiologists.
  • The dermatomyositis epidemiology model developed by the publisher is easy to navigate, interactive with a dashboard, and epidemiology based on transparent and consistent methodologies. Moreover, the model supports the data presented in the report and showcases disease trends over the 10-year forecast period using reputable sources.
Key Assessments
  • Patient Segmentation
  • Disease Risk and Burden
  • Risk of Disease by Segmentation
  • Factors Driving Growth in a Specific Patient Population
Geographies Covered
  • The United States
  • EU4 (Germany, France, Italy, and Spain) and the United Kingdom
  • Japan
Study Period: 2019-2032

Table of Contents

1. Key Insights2. Report Introduction
3. Dermatomyositis Epidemiology Overview at a Glance
3.1. Patient Share (%) Distribution of Dermatomyositis in 2019
3.2. Patient Share (%) Distribution of Dermatomyositis in 2032
4. Methodology of Dermatomyositis Epidemiology5. Executive Summary of Dermatomyositis
6. Disease Background and Overview
6.1. Introduction of Dermatomyositis
6.2. Types of Dermatomyositis
6.3. Signs and Symptoms
6.4. Clinical Manifestation of Dermatomyositis
6.5. Causes
6.6. Complications
6.7. Pathophysiology
6.8. Diagnosis
6.8.1. Diagnostic Criteria
6.8.1.1. Bohan and Peter's Classification Criteria for Polymyositis and Dermatomyositis
6.8.2. The Myositis Association: Diagnostic Criteria for Dermatomyositis
6.8.3. Diagnostic Criteria for Polymyositis and Dermatomyositis
6.8.4. Differential Diagnosis
6.8.5. Diagnostic Guidelines
6.8.5.1. The European League Against Rheumatism/American College of Rheumatology Classification Criteria for Adult and Juvenile IIM
6.8.5.2. Clinical Practice Guidance for Juvenile Dermatomyositis (JDM) 2018: Japan
6.8.5.3. Single Hub and Access Point for Pediatric Rheumatology in Europe (SHARE): Consensus-based Recommendations for the Management of Juvenile Dermatomyositis
6.8.6. Diagnostic Algorithm
7. Patient Journey
8. Epidemiology and Patient Population
8.1. Key Findings
8.2. Assumptions and Rationale
8.2.1. Total Diagnosed Prevalent Cases of Dermatomyositis
8.2.1.1. Diagnosed Prevalent Cases of Juvenile Dermatomyositis
8.2.1.2. Diagnosed Prevalent Cases of Adult Dermatomyositis
8.2.2. Age-specific Diagnosed Prevalent Cases of Dermatomyositis
8.2.3. Gender-specific Diagnosed Prevalent Cases of Dermatomyositis
8.2.4. Severity-specific Diagnosed Prevalent Cases of Dermatomyositis
8.2.5. Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis
8.2.6. Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis
8.3. Total Diagnosed Prevalent Cases of Dermatomyositis in the 7MM
8.4. The US
8.4.1. Total Diagnosed Prevalent Cases of Dermatomyositis in the US
8.4.2. Age-specific Diagnosed Prevalent Cases of Dermatomyositis in the US
8.4.3. Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in the US
8.4.4. Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US
8.4.5. Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US
8.4.6. Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US
8.5. EU4 and the UK
8.5.1. Total Diagnosed Prevalent Cases of Dermatomyositis in the EU4 and the UK
8.5.2. Age-specific Diagnosed Prevalent Cases of Dermatomyositis in the EU4 and the UK
8.5.3. Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in the EU4 and the UK
8.5.4. Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in the EU4 and the UK
8.5.5. Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in the EU4 and the UK
8.5.6. Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in the EU4 and the UK
8.6. Japan
8.6.1. Total Diagnosed Prevalent Cases of Dermatomyositis in Japan
8.6.2. Age-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan
8.6.3. Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan
8.6.4. Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan
8.6.5. Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan
8.6.6. Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan
9. KOL Views10. Unmet Needs
11. Appendix
11.1. Bibliography
11.2. Acronyms and Abbreviations
12.3. Report Methodology
12. Publisher Capabilities13. Disclaimer14. About the Publisher
List of Tables
Table 1: Summary of Dermatomyositis Epidemiology (2019-2032)
Table 2: Comparison of Juvenile Dermatomyositis and Adult Dermatomyositis
Table 3: Cutaneous Manifestations of Adult Dermatomyositis
Table 4: Systemic Manifestations of Dermatomyositis in Adults and Children
Table 5: Bohan and Peter Classification Criteria for Polymyositis and Dermatomyositis
Table 6: Diagnostic Criteria for Dermatomyositis
Table 7: The European League Against Rheumatism/American College of Rheumatology Classification Criteria for Adult and Juvenile IIM
Table 8: Currently Used ‘Guidance for Diagnosis in Specified Pediatric Chronic Diseases
Table 9: Recommendations Regarding Diagnosis
Table 10: Classification Tree for a Subtype of IIM
Table 11: Total Diagnosed Prevalent Cases of Dermatomyositis in the 7MM (2019-2032)
Table 12: Total Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Table 13: Age-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Table 14: Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Table 15: Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Table 16: Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Table 17: Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Table 18: Total Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Table 19: Age-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Table 20: Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Table 21: Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Table 22: Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Table 23: Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Table 24: Total Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Table 25: Age-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Table 26: Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Table 27: Severity-specific Diagnosed Prevalent cases of Dermatomyositis in Japan (2019-2032)
Table 28: Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Table 29: Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
List of Figures
Figure 1: Signs and Symptoms of Dermatomyositis
Figure 2: Contributing Factors to Dermatomyositis
Figure 3: Causes of Dermatomyositis
Figure 4: Complications Associated With Dermatomyositis
Figure 5: The Vicious Pro-inflammatory Circle in Dermatomyositis
Figure 6: Patient Journey
Figure 7: Total Diagnosed Prevalent Cases of Dermatomyositis in the 7MM (2019-2032)
Figure 8: Total Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Figure 9: Age-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Figure 10: Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Figure 11: Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Figure 12: Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Figure 13: Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in the US (2019-2032)
Figure 14: Total Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Figure 15: Age-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Figure 16: Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Figure 17: Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Figure 18: Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 the UK (2019-2032)
Figure 19: Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in EU4 and the UK (2019-2032)
Figure 20: Total Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Figure 21: Age-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Figure 22: Gender-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Figure 23: Severity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Figure 24: Chronicity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Figure 25: Comorbidity-specific Diagnosed Prevalent Cases of Dermatomyositis in Japan (2019-2032)
Figure 26: Unmet Needs