Biomedical Image Synthesis and Simulation: Methods and Applications presents the basic concepts and applications in image-based simulation and synthesis used in medical and biomedical imaging. The first part of the book introduces and describes the simulation and synthesis methods that were developed and successfully used within the last twenty years, from parametric to deep generative models. The second part gives examples of successful applications of these methods. Both parts together form a book that gives the reader insight into the technical background of image synthesis and how it is used, in the particular disciplines of medical and biomedical imaging. The book ends with several perspectives on the best practices to adopt when validating image synthesis approaches, the crucial role that uncertainty quantification plays in medical image synthesis, and research directions that should be worth exploring in the future.
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Table of Contents
1. Introduction to Medical and Biomedical Image Synthesis2. Parametric model-based approaches
3. Monte Carlo Simulations for Medical and Biomedical Applications
4. Medical Image Synthesis using Segmentation and Registration
5. Dictionary Learning for Medical Image Synthesis
6. Convolutional Neural Networks for Image Synthesis
7. Generative Adversarial Networks for Medical Image Synthesis
8. Autoencoders and Variational Autoencoders in Medical Image Analysis
9. Optimization of the MR Imaging Pipeline Using Simulation
10. Synthesis for Image Analysis Across Modalities: Application to Registration and Segmentation
11. Medical Image Harmonization Through Synthesis
12. Medical Image Super-Resolution With Deep Networks
13. Medical Image Denoising
14. Data Augmentation for Medical Image Analysis
15. Unsupervised Abnormality Detection in Medical Images with Deep Generative Methods
16. Regularising Disentangled Representations with Anatomical Temporal Consistency
17. Image Imputation in Cardiac MRI and Quality Assessment
18. Image Synthesis for Low-count PET Acquisitions: Lower Dose, Shorter Time
19. PET/MRI attenuation correction
20. Image Synthesis for MRI-only Radiotherapy Treatment Planning
21. Review of Cell Image Synthesis for Image Processing
22. Generative Models for Synthesis of Colorectal Cancer Histology Images
23. Spatiotemporal Image Generation for Embryomics Applications
24. Biomolecule Trafficking and Network Tomography-based Simulations
25. Validation and Evaluation Metrics for Medical and Biomedical Image Synthesis
26. Uncertainty Quantification in Medical Image Synthesis
27. Future trends
