Tissue Engineering. Edition No. 3

Table of Contents

1. An introduction to tissue engineering; the topic and the book
Jorge Alfredo Uquillas, Lorenzo Moroni and Jan de Boer
2. Stem cells
Mark F. Pittenger and Candace L. Kerr
3. Tissue formation during embryogenesis
Marcel Karperien, Bernard A.J. Roelen, Robert Passier and Susan Gibbs
4. Cellular signaling
Vanessa LaPointe and Kristopher A. Kilian
5. Extracellular matrix as a bioscaffold for tissue engineering
Brian M. Sicari, Ricardo Londono, Jenna L. Dziki and Stephen F. Badylak
6. Synthetic biomaterials
Ana A. Aldana, Jurica Bauer and Matthew B. Baker
7. Degradation of biomaterials
Clara Grace Hynes, Emily Morra, Pamela Walsh and Fraser Buchanan
8. Cellematerial interactions
Hannah Donnelly, Steven Vermeulen, Monica Tsimbouri and Matthew J. Dalby
9. Biomaterials discovery: experimental and computational approaches
Andrew L. Hook, Aur�lie Carlier, Morgan R. Alexander and David A. Winkler
10. Microfabrication technology in tissue engineering
Minghao Nie, Roman Truckenm�ller and Shoji Takeuchi
11. Scaffold design and fabrication
Dietmar W. Hutmacher, Biranche Tandon and Paul D. Dalton
12. Controlled release strategies in tissue engineering
Jeffrey J. Rice, Mika�l M. Martino, Sharan Bobbala, Evan A. Scott and Jeffrey A. Hubbell
13. Bioreactors: enabling technologies for research and manufacturing
Dominik Egger, Sabrina Nebel, Marius Gensler, Sebastian Kreb, Jan Hansmann and Cornelia Kasper
14. Strategies to promote vascularization, survival, and functionality of engineered tissues
Miriam Filippi, Thomas Sp�ter, Marietta Herrmann, Matthias W. Laschke, Arnaud Scherberich and Sophie Verrier
15. Skin tissue engineering and keratinocyte stem cell therapy
Rosalind Hannen, John Connelly, Simon Myers and Nkemcho Ojeh
16. Cartilage and bone regeneration
Anders Lindahl, Mats Brittberg, David Gibbs, Jonathan I. Dawson, Janos Kanczler, Cameron Black, Rahul Tare and Richard OC. Oreffo
17. Tissue engineering of the nervous system
Paul D. Dalton, Kelly L. O'Neill, Ana Paula P�go, Giles W. Plant, David R. Nisbet, Martin Oudega, Gary A. Brook and Alan R. Harvey
18. Principles of cardiovascular tissue engineering
Saray Chen and Smadar Cohen
19. Tissue engineering of organ systems
Adam M. Jorgensen and Anthony Atala
20. Product and process design: scalable and sustainable tissue-engineered product manufacturing
Evan Claes, Tommy Heck, Maarten Sonnaert, Filip Donvil, Ana�s Schaschkow, Tim Desmet and Jan Schrooten
21. Clinical translation
Johan Joly, Marina Marechal, Dieter Van Assche, Malcolm Moos, Jr. and Frank P. Luyten

Authors

Clemens van Blitterswijk KNAW (The Royal Netherlands Academy of Arts and Sciences), The Netherlands. Clemens van Blitterswijk graduated as cell biologist from Leiden University in 1982, defending his PhD thesis in 1985 at the same university. Today his research focuses on tissue engineering and regenerative medicine, forming a unique basis of multidisciplinary research between materials and life sciences. Van Blitterswijk has authored and co-authored more than 380 peer reviewed papers (H index 90, Scopus); is one of the most frequently cited Dutch scientists in TE; the applicant and co-applicant of over 100 patents; has guided 50 PhD candidates through their thesis as supervisor or co-supervisor and currently has 30 PhD candidates under his supervision. Dr. van Blitterswijk received a number of prestigious international awards including the George Winter award of the European society for Biomaterials, the Career Achievement Award of the Tissue Engineering and Regenerative Medicine International Society and is a member of the KNAW (The Royal Netherlands Academy of Arts and Sciences). Jan De Boer Professor, Department of Biomedical Engineering, The Netherlands. Jan de Boer is an experienced University Professor and Chief Scientific Officer with a demonstrated history of working in academia and biotech. As a research professional he is skilled in Stem Cells, Biomaterial Engineering and Regenerative Medicine.� Jan is interested in the molecular complexity of cells and how molecular circuits are involved in cell and tissue function. With a background in mouse and Drosophila genetics, he entered the field of biomedical engineering in 2002 and has since focused on understanding and implementing molecular biology in the field of tissue engineering and regenerative medicine. His research is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology, to streamline the wealth of biological knowledge to real clinical applications.