Venous Ulcers, Second Edition, provides a comprehensive synthesis of evidence-based recommendations and the highest level of expertise from a leading group of doctors, which is a fundamental constituent for the appropriate management of nonhealing venous wounds in everyday practice. This book offers a fertile environment for a complete understanding of genetics and molecular and biochemical mechanisms that lead to the development and progression of venous ulcers, which is essential for elucidating the underlying pathophysiology and can be utilized for developing novel therapies and accessing previously inaccessible areas of research. Socioeconomic impact, impact on health-related quality of life, the clinical course of the disease, and diagnostic algorithms are elaborated in detail. All currently available treatment modalities are explained in a clinically applicable approach with particular emphasis on operative technique, technical feasibility, success rates (both clinical and technical), and side effects. Lastly, this book elaborates on special diagnostic considerations and management of the most complex patients, often requiring the highest level of expertise for successful treatment.
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Table of Contents
Section 1: Chronic venous insufficiency
basic considerations
1. Pathophysiology of chronic venous disease: genetic, molecular and biochemical mechanisms
2. Venous hemodynamics and microcirculation in chronic venous insufficiency
3. Venous ulcers of the lower extremity: etiology, risks and predictive factors
4. Venous ulcers of the lower extremity: epidemiology and socio-economic burden
Section 2: Clinical evaluation and diagnostic modalities
5. Initial clinical evaluation in patients with chronic venous insufficiency
6. Ultrasound evaluation of lower extremity chronic venous disease
7. The diagnosis of major venous outflow obstruction in chronic venous insufficiency
8. Hypercoagulable states associated with chronic venous insufficiency
9. The chronically swollen leg with ulcers
finding the cause: theory and practice
10. Lower extremity wounds associated with mixed venous and arterial insufficiency and relevant differential diagnosis
11. Assessment tools and wound documentation for patients with chronic venous insufficiency
Section 3: Non-operative management of chronic venous insufficiency and wound care
12. Compression therapy in venous leg ulcers
13. Wound healing: adjuvant therapy and treatment adherence
14. Negative pressure wound healing for venous ulcers
15. Medical therapies for chronic venous insufficiency
16. Treatment modalities for the management of nonhealing wounds in patients with chronic venous insufficiency
17. Deep vein thrombosis and prevention of postthrombotic syndrome
18. Improving treatment outcomes
management of coexisting comorbidities in patients with venous ulcers
19. Emerging modalities in local treatment of venous ulcers: advanced dressings, bioengineering, and biologics
Section 4: Operative and endovascular procedures for chronic venous insufficiency
20. Benefits of superficial venous intervention (surgery or endovenous ablation) in the treatment of venous leg ulceration
21. Superficial surgery and perforator interruption in the treatment of venous leg ulcers
22. Endovascular techniques for superficial vein ablation in treatment of venous ulcers
23. Treatment of chronic venous insufficiency with foam sclerotherapy
24. Ultrasound guidance for endovenous treatment
25. Iliac vein stenting in venous leg ulcers
26. Venous valve reconstructions in patients with severe chronic venous insufficiency
Section 5: Special considerations
27. Treatment of recalcitrant venous ulcers with free tissue transfer for limb salvage
28. Management of venous ulcers in patients with congenital vascular malformations
29. Lymphatic disorders in pathogenesis of chronic venous insufficiency
Authors
Cynthia K. Shortell Department of Surgery, Duke University Medical Center, Durham, NC, USA.Dr. Cynthia K. Shortell is a Professor of Surgery at Duke University School of Medicine, former Chief of Vascular and Endovascular Surgery, and Executive Vice Chair for the Department of Surgery at Duke University Medical Center. For decades, Dr. Shortell has worked relentlessly to advance the management of patients with carotid artery disease. Nationally, Dr. Shortell holds numerous distinguished recognitions, serves as Associate Editor of the Journal of Vascular Surgery and is an elected member of many national and international societies and organizations, including the Society for Vascular Surgery, and the International Society of Surgery.
Jovan N. Markovic Department of Surgery, Duke University Medical Center, Durham, NC, USA.Dr. Jovan N. Markovic is a staff MD at Duke University School of Medicine and Medical Center, where during his specialization in general surgery, he became extensively involved in advancing the care of patients with complex vascular disorders. Dr. Markovic currently serves as a key reviewer for the Journal of Vascular Surgery and has published books, numerous book chapters, peer-reviewed studies, and national and international guidelines on the treatment of patients with vascular disorders.
