Transdermal Patch Market Opportunity, Patch Dosage, Price & Clinical Trials Insight 2030

Global Transdermal Patch Market Opportunity, Patch Dosage, Price & Clinical Trials Insight 2030 Report Highlights & Findings:

Global Transdermal Patch Market Opportunity: US$ 18 Billion By 2030
US Currently Dominating Global Transdermal Patch Market: > US$ 4 Billion
China To Emerge Growing Market For Transdermal Patches By 2030
Currently More Than 60 Patches Are Approved Globally
Approved Patches Market Availability, Dosage & Price Analysis
Global Transdermal Market Insights By Region & Indications
Comprehensive Insight On Clinical Trials By Company, Indication & Phase
Competitive Landscape: Insight On Key Companies

The global market for transdermal patches has rapidly transformed into a dynamic and intensely competitive arena, where both emerging players and established firms are continually innovating to address the increasing demands of patients. These patches facilitate a controlled and consistent release of therapeutic agents through the skin, serving a diverse array of medical conditions, including pain management, smoking cessation, hormone replacement therapy, and more. An outstanding example of their success is the nicotine patch, which gained popularity as a smoking cessation aid in the early 2000s. Since then, the spectrum of conditions treated by transdermal patches has broadened considerably, now encompassing treatments for ADHD, hormone deficiencies, and nausea, among others. Although they tend to be pricier than conventional drug delivery methods, transdermal patches are witnessing consistent market growth, propelled by their advantageous safety and efficacy profiles.

An essential element in the ongoing expansion of the global transdermal patch market is the attainment of regulatory approval. Successful validations from regulatory authorities are crucial in affirming the credibility of transdermal patches as a viable drug delivery system. For example, Zydus Lifesciences received the final FDA approval for its scopolamine transdermal system aimed at treating nausea and vomiting in August 2024. Likewise, Sino Biopharmaceutical obtained NMPA approval in September 2024 for its rivastigmine transdermal patch, intended for the treatment of mild to moderate Alzheimer’s disease. This approval represents a significant achievement, as it is the first domestically manufactured rivastigmine patch authorized for sale in China, emphasizing the increasing acceptance of transdermal patches on a global scale.

The commercial viability of transdermal patches is further enhanced significantly by ongoing innovations in drug delivery systems. For instance, Anodyne Nanotech’s HeroPatch™ platform has demonstrated encouraging preclinical outcomes in the transdermal administration of GLP-1 receptor agonists, including semaglutide, achieving over 50% bioavailability. This advancement has the potential to transform the management of chronic diseases such as diabetes by providing a needle-free, weekly alternative to traditional injections. Clinical trials for the HeroPatch™ are anticipated to commence in 2025, reinforcing the role of transdermal patches as a pivotal element in drug delivery technology.

In another momentous development, researchers at Central South University in China have created a long-acting transdermal delivery system for Guanfacine, a non-stimulant medication for ADHD. This patch is designed to enhance drug release and ensure skin safety, with the capability of supporting treatment cycles lasting up to three days, thus offering a more convenient and patient-centric solution. Furthermore, Biotts, a Polish company specializing in drug delivery, is developing an insulin transdermal patch utilizing its MTC-Y carrier technology. This innovation allows for insulin delivery over a period of up to five days, providing a stable and extended alternative to the daily injections typically required by individuals with type 1 diabetes. Positive results from animal studies have been reported, and Biotts aims to begin human trials by 2027, which could significantly improve diabetes management for countless patients.

At present, there are multiple transdermal patches undergoing clinical trials, highlighting the significant potential of this method for drug delivery. These patches are being investigated across a growing array of therapeutic areas, such as chronic pain management, diabetes treatment, and even vaccination. With nearly 70 transdermal patches already receiving global approval, the market's growth trajectory appears strong, driven by technological advancements and an expanding spectrum of treatable conditions via transdermal means. Although challenges remain, including skin irritation and limitations in delivering higher drug dosages through a single patch, researchers are making progress in addressing these issues. The outlook for transdermal patches is promising, with ongoing enhancements in drug formulation, patch design, and patient adherence anticipated to further propel market growth.

In conclusion, transdermal patches are on the verge of becoming a widely accepted drug delivery method, providing considerable advantages in terms of patient convenience, reliable therapeutic delivery, and minimized side effects. As the market continues to grow, the clinical and commercial success of transdermal patches is expected to significantly influence the global pharmaceutical landscape, offering patients and healthcare providers more effective, less invasive, and more user-friendly alternatives to conventional drug delivery systems.

1. Introduction To Transdermal Patch

1.1 Overview Of Transdermal Patch
1.2 Relevance Of Transdermal Patch

2. Transdermal Patches Classification

2.1 Single/ Multiple Layer Drug In Adhesive
2.2 Reservoir Transdermal Patches
2.3 Matrix Based Transdermal Patches
2.4 Vapor Patch
2.5 Active & Passive Patch

3. Mechanism Of Transdermal Patch Drug Delivery

3.1 Properties Of Transdermal Therapeutics
3.2 Components Of Transdermal Patch
3.3 Mechanism Of Motion Sickness, Nicotine & Female Contraceptive Transdermal Patch
3.4 Transdermal Patch v/s Traditional Drug Delivery Methods

4. Global Transdermal Patch Market Outlook

4.1 Current Market Scenario
4.2 Future Market Opportunity

5. Global Transdermal Patch Market Trends By Region

5.1 US
5.2 Europe
5.3 China
5.4 Japan
5.5 South Korea
5.6 UK

6. Global Patch Clinical Pipeline By Company, Indication & Phase

6.1 Research
6.2 Preclinical
6.3 Phase-I
6.4 Phase-I/II
6.5 Phase-II
6.6 Phase-III
6.7 Preregistration
6.8 Registered

7. Global Marketed Transdermal Patch Clinical Insight

8. Transdermal Patches For Cardiovascular Diseases - Market Availability, Dosage & Price Analysis

8.1 Nitroglycerin Transdermal Patch
8.1.1 Nitro-Dur
8.1.2 Nitro TD Patch A
8.1.3 Generic Nitroglycerin Transdermal Patch
8.2 Clonidine Transdermal Patch
8.2.1 Catapres-TTS
8.2.2 Generic Clonidine Transdermal Patch
8.3 Bisoprolol Transdermal Patch (Bisono)

9. Transdermal Analgesic Patches - Market Availability, Dosage & Price Analysis

9.1 Fentanyl Transdermal Patch
9.1.1 Duragesic/Durogesic
9.1.2 Durotep MT
9.1.3 OneDuro
9.1.4 Generic Fentanyl Transdermal Patch
9.1.5 Fentos
9.1.6 Fentadur
9.1.7 Generic Fentanyl Citrate Transdermal Patch
9.2 Buprenorphine Transdermal Patch
9.2.1 Butrans
9.2.2 Bunov
9.2.3 Sevodyne
9.2.4 Transtec
9.2.5 Generic Buprenorphine Transdermal Patch
9.3 Diclofenac Transdermal Patch
9.3.1 Zicthoru
9.3.2 Flector
9.3.3 Licart
9.4 Ketoprofen Transdermal Patch (Mohrus)
9.5 Lidocaine Transdermal Patch
9.5.1 Versatis
9.5.2 ZTlido
9.5.3 Penles
9.5.4 Rapydan
9.6 Capsaicin Transdermal Patch (Qutenza)
9.7 Methyl Salicate Transdermal Patch
9.7.1 Salonpas
9.7.2 Tokuhon
9.8 Glycol Salicylate Transdermal Patch (Tokuhon E)
9.9 Flurbiprofen Transdermal Patch
9.9.1 Loqoa
9.9.2 Yakuban Tape
9.9.3 Transact Lat

10. Transdermal Patch In Hormonal Therapy - Market Availability, Dosage & Price Analysis

10.1 Estradiol Transdermal Patch
10.1.1 Alora
10.1.2 Vivelle-Dot
10.1.3 Minivelle
10.1.4 Climara
10.1.5 Menostar
10.1.6 FemSeven
10.1.7 Estrana
10.1.8 Generic Estradiol Transdermal Patch
10.2 Testosterone Transdermal Patch (Androderm)
10.3 Estradiol/ Norethisterone Transdermal Patch
10.3.1 Xulane/Ortho Evra
10.3.2 Combipatch
10.3.3 Menoaid Combi Patch
10.3.4 Evorel Conti
10.4 Estradiol/Levonorgestrel Transdermal Patch
10.5 Ethinyl Estradiol/Levonorgestrel (Twirla)
10.6 Ethinyl Estradiol/Gestodene (Apleek)

11. Transdermal Patches For Neurological Disorders - Market Availability, Dosage & Price Analysis

11.1 Scopolamine Transdermal Patch (Transderm-Scop)
11.2 Selegiline Transdermal Patch (Emsam)
11.3 Methylphenidate Transdermal Patch (Daytrana)
11.4 Dextroamphetamine Transdermal Patch (Xelstrym)
11.5 Blonanserin Transdermal Patch (Lonasen)
11.6 Asenapine Transdermal Patch (Secuado)
11.7 Rivastigmine Transdermal Patch
11.7.1 Exelon
11.7.2 Generic Rivastigmine Transdermal Patch
11.8 Rotigotine Transdermal Patch (Neupro)
11.9 Ropinirole Hydrochloride (Haruropi Tape)
11.10 Donepezil Transdermal Patch (Adlarity)

12. Patches For Other Conditions - Market Availability, Dosage & Price Analysis

12.1 Nicotine Transdermal Patch (Nicoderm CQ/ Nicotinell TTS)
12.2 Oxybutynin Transdermal Patch (Oxytrol/Kentera)
12.3 Granisetron Transdermal Patch (Sancuso)
12.4 Emedastine Transdermal Patch (Allesaga)
12.5 Fibrin Sealant Transdermal Patch
12.5.1 Evarrest
12.5.2 TachoSil
12.6 5-Aminolevulinic Acid Transdermal Patch (Alacare)
12.7 Tulobuterol Transdermal Patch
12.7.1 Tulo-Touch
12.7.2 Hokunarin

13. Global Transdermal Patch Market Dynamics

13.1 Favorable Market Parameters
13.2 Commercialization Challenges

14. Competitive Landscape

14.1 AbbVie
14.2 Bayer HealthCare Pharmaceuticals
14.3 Corium International
14.4 Endo Pharmaceuticals
14.5 Hisamitsu Pharmaceutical
14.6 Luye Pharma
14.7 Noven Pharmaceuticals
14.8 Novartis
14.9 Purdue Pharma
14.10 Scilex Pharmaceuticals
14.11 Searchlight Pharma
14.12 Somerset Pharmaceuticals
14.13 Teikoku Seiyaku
14.14 Teva Pharmaceuticals
14.15 UCB
14.16 DURECT Corporation
14.17 Senju Pharmaceutical

List of Figures

Figure 1-1: Transdermal Permeation - Steps Involved
Figure 1-2: Transdermal Patch - Ideal Properties
Figure 2-1: Commercially Available Transdermal Patch Types
Figure 2-2: Multilayer Transdermal Patch
Figure 2-3: Reservoir Transdermal Patch System
Figure 2-4: Matrix Based Transdermal Patches
Figure 3-1: Transdermal Therapeutics - Properties
Figure 3-2: Transdermal Patch - Components
Figure 3-3: Permeation Enhancer - Types
Figure 3-4: Iontophoresis - Schematic Representation
Figure 3-5: Scopolamine Transdermal Patch - Mechanism
Figure 3-6: Nicotine Transdermal Patch - Mechanism
Figure 3-7: Female Contraceptive Transdermal Patch - Mechanism
Figure 3-8: Traditional Drug Delivery Methods - Challenges
Figure 3-9: Transdermal Patch - Advantages
Figure 3-10: Consistent Drug Supply By Transdermal Patch
Figure 4-1: Global - Transdermal Patch Market Size (US$ Billion), 2024 - 2030
Figure 4-2: Global Transdermal Patch Market By Region (US$ Billion), 2024
Figure 4-3: Global Transdermal Patch Market By Region (%), 2024
Figure 4-4: Global Transdermal Patch Market By Region (US$ Billion), 2030
Figure 4-5: Global Transdermal Patch Market By Region (%), 2030
Figure 8-1: Nitro-Dur - Price Per Unit & Supply Of Transdermal Films (US$), March’2025
Figure 8-2: Nitro TD Patch A - Price Per Unit & Supply Of Transdermal Films (US$), February’2025
Figure 8-3: Generic Nitroglycerin Transdermal Patch - Price Per Unit & Supply (US$), February’2025
Figure 8-4: Catapres-TTS - FDA Approval & First Generic Approval Year
Figure 8-5: Catapres-TTS - Price Per Unit & Supply (US$), February’2025
Figure 8-6: Catapres-TTS Transdermal Patch - Recommended Initial & Incremented Dose (mg/Week)
Figure 8-7: Generic Clonidine Transdermal Patch - Price Per Unit & Supply (US$), February’2025
Figure 8-8: Bisono - Approval Year By Indication
Figure 8-9: Bisono - Price Per Unit By Dose (US$), February’2025
Figure 8-10: Bisono - Initial & Maximum Recommended Dose (mg/hr)
Figure 9-1: Duragesic - Approval Year By Region
Figure 9-2: Durotep MT - Price Per Unit By Dose (US$), February’2025
Figure 9-3: OneDuro - Price Per Unit By Dose (US$), February’2025
Figure 9-4: Generic Fentanyl Transdermal Patch - Price Per Unit & Supply In US (US$), March’2025
Figure 9-5: Fentos - Price Per Unit By Dose (US$), February’2025
Figure 9-6: Fentos - Annual Sales (US$), 2020-2024
Figure 9-7: Generic Fentanyl Citrate Transdermal Patch - Price Per Unit By Dose (US$), February’2025
Figure 9-8: Butrans - FDA Approval Year By Dose
Figure 9-9: US - Butrans FDA Approval & 1st Generic Approval Year
Figure 9-10: Butrans - Approval Year By Region
Figure 9-11: Butrans - Price Per Unit & Supply In US (US$), March’2025
Figure 9-12: Butrans - Initial & Maximum Recommended Dose (mcg/hr)
Figure 9-13: Butrans - Price Per Unit & Supply In UK (US$), February’2025
Figure 9-14: Bunov - Initial & Maximum Recommended Dose (mg/hr)
Figure 9-15: Sevodyne - Price Per Supply (US$), February’2025
Figure 9-16: Transtec - Price Per Supply In UK (US$), February’2025
Figure 9-17: Generic Buprenorphine Transdermal Patch - Price Per Unit & Supply In US (USS), March’2025
Figure 9-18: Zicthoru - Price Per Unit & Supply (US$), February’2025
Figure 9-19: Zicthoru - Annual Sales (US$), 2021-2024
Figure 9-20: Branded & Generic Flector Patch - Price Per Unit & Supply In US (US$), March’2025
Figure 9-21: Licart - Price Per Unit & Supply In US (US$), March’2025
Figure 9-22: Mohrus - Price Per Supply By Dose (US$), February’2025
Figure 9-23: Mohrus - Annual Sales (US$), 2020-2024
Figure 9-24: Versatis - Price Per Supply By Region (US$), February’2025
Figure 9-25: ZTlido - Price Per Unit & Supply (US$), February’2025
Figure 9-26: Qutenza - Price Per Unit By Region (US$), February’2025
Figure 9-27: Salonpas - Price Per Unit & Supply In US (US$), March’2025
Figure 9-28: Generic Methyl Salicylate Patch - Price Per Unit & Supply In US (US$), March’2025
Figure 9-29: Tokuhon - Price Per Supply (US$), February’2025
Figure 9-30: Yakuban Tape - Price Per Supply Of 60mg Tape (US$), February’2025
Figure 9-31: Yakuban Tape - Price Per Supply Of 20mg Tape (US$), February’2025
Figure 9-32: TransAct Lat - Price Per Supply By Online Pharmacy (US$), February’2025
Figure 10-1: Alora - FDA Approval Year By Dose
Figure 10-2: Alora - Recommended Dose For Treatment Of Vaginal Atrophy & Postmenopausal Osteoporosis (mg/Day Twice In A Week)
Figure 10-3: Vivelle-Dot - FDA Approval & First Generic Approval Year
Figure 10-4: Vivelle-Dot - Price Per Unit & Supply In US (US$), March’2025
Figure 10-5: Vivelle-Dot - Recommended Dose (mg/Day Twice a Week)
Figure 10-6: Vivelle-Dot - Annual Sales (US$), 2020-2024
Figure 10-7: Minivelle - FDA Approval Year By Dose
Figure 10-8: Minivelle - FDA Approval & First Generic Approval Year
Figure 10-9: US - Minivelle Patent Issue & Expiration Year
Figure 10-10: Minnivelle - Price Per Unit & Supply In US (US$), March’2025
Figure 10-11: Minivelle - Recommended Dose By Indication (mg/Day)
Figure 10-12: Minivelle - Annual Sales (US$), 2020-2024
Figure 10-13: Climara - FDA Approval Year By Dose
Figure 10-14: Climara - FDA Approval & First Generic Approval Year
Figure 10-15: Climara - Price Per Unit & Supply In Canada (US$), February’2025
Figure 10-16: Menostar - Price Per Unit & Supply In US (US$), March’2025
Figure 10-17: FemSeven - Price Per Unit & Supply (Euro/US$), February’2025
Figure 10-18: FemSeven - Initial & Increased Dosage For Postmenopausal Symptoms (mg/hr)
Figure 10-19: Estrana - Price Per Supply (US$), February’2025
Figure 10-20: Estrana - Annual Sales (US$), 2020-2024
Figure 10-21: Generic Estradiol Transdermal Patch - Price Per Unit & Supply Of Twice Weekly Patch In US (US$), March’2025
Figure 10-22: Generic Estradiol Transdermal Patch - Price Per Unit & Supply Of Weekly Patch In US (US$), March’2025
Figure 10-23: Androderm - Price Per Unit & Supply In US (US$), March’2025
Figure 10-24: Androderm - Recommended Initial & Maintainence Dose For Treatment of Hypogonadism (mg/day)
Figure 10-25: Xulane - FDA Approval & First Generic Approval Year
Figure 10-26: Ortho Evara - FDA & EMA Approval Year
Figure 10-27: Xulane & Zafemy - Price Per Unit & Supply In US (US$), March’2025
Figure 10-28: Ethinyl Estradiol/Norelgestromin Patch - Recommended Schedule for Achieving Birth Control Effect (Days)
Figure 10-29: Evra - Price Per Unit & Supply In UK (US$), February’2025
Figure 10-30: CombiPatch - Price Per Unit & Supply In US (US$), March’2025
Figure 10-31: CombiPatch - Price Per Unit & Supply In Canada (US$), February’2025
Figure 10-32: CombiPatch - Annual Sales (US$), 2020-2024
Figure 10-33: Estradiol/Levonorgestrel - Approval Year By Region
Figure 10-34: Climara Pro - Price Per Unit & Supply In US (US$), March’2025
Figure 10-35: FemSeven Conti - Price Per Unit & Supply In UK (US$), February’2025
Figure 10-36: US - Twirla Patent Issue & Expiration Year
Figure 10-37: Twirla - Price Per Unit & Supply (US$), March’2025
Figure 10-38: Twirla - Recommended Schedule For Achieving Birth Control Effect (Days)
Figure 11-1: Transderm-Scop - FDA Approval & 1st Generic Approval Year
Figure 11-2: Transderm-Scop - Price Per Unit & Supply (US$), March’2025
Figure 11-3: Scopolamine - Price Per Unit & Supply (US$), March’2025
Figure 11-4: Emsam - Price Per Unit & Supply (US$), March’2025
Figure 11-5: Daytrana - FDA Approval & Patent Exclusivity Year
Figure 11-6: US - Daytrana Patent Issue & Expiration Year
Figure 11-7: Daytrana - Price Per Unit & Supply (US$), March’2025
Figure 11-8: Daytrana - Annual Sales (US$), 2020-2024
Figure 11-9: Xelstrym - Price Per Unit & Supply (US$), March’2025
Figure 11-10: Xelstrym - Annual Sales (US$), 2023-2024
Figure 11-11: Lonasen - Price Per Unit in Japan (US$), February’2025
Figure 11-12: US - Secuado Patent Issue & Expiration Year
Figure 11-13: Secuado - Price Per Unit & Supply (US$), March’2025
Figure 11-14: Secuado - Recommended Initial & Incremented Dose (mg/Day)
Figure 11-15: Secuado - Annual Sales (US$), 2020-2024
Figure 11-16: Exelon - Approval Year By Region
Figure 11-17: US - Exelon FDA Approval Year & 1st Generic Approval Year
Figure 11-18: Exelon - Price Per Unit & Supply In US (US$), March’2025
Figure 11-19: Generic Rivastigmine Patch - Price Per Unit & Supply (US$), March’2025
Figure 11-20: Neupro - Approval Year By Region
Figure 11-21: US - Neupro Approval Year By Indication
Figure 11-22: Neupro - Patent Issue & Expiration Year
Figure 11-23: Neupro - Price Per Unit & Supply (US$), March’2025
Figure 11-24: Neupro - Initial & Maximum Recommended Dose for Early Stage Parkinson (mg/day)
Figure 11-25: Neupro - Initial & Maximum Recommended Dose for Late Stage Parkinson (mg/day)
Figure 11-26: Neupro - Initial & Maximum Recommended Dose for Restless Leg Syndrome (mg/day)
Figure 11-27: Global - Neupro Sales (US$ Million), 2020-2024
Figure 11-28: Haruropi Tape Patch - Price Per Unit In Japan (US$), February’2025
Figure 11-29: Haruropi Tape - Initial & Maximum Recommended Dose (mg/day)
Figure 11-30: Haruropi - Annual Sales (US$), 2020-2024
Figure 11-31: Adlarity - Price Per Unit & Supply In US (US$), February’2025
Figure 12-1: Nicotine Transdermal Patch - Approval Year By Region
Figure 12-2: Nicoderm CQ - Price Per Unit & Supply (US$), March’2025
Figure 12-3: Generic Nicotine Patch - Price Per Unit & Supply Of 7mg/24hr Transdermal Patches (US$), March’2025
Figure 12-4: Generic Nicotine Patch - Price Per Unit & Supply Of 14mg/24hr Transdermal Patches (US$), March’2025
Figure 12-5: Generic Nicotine Patch - Price Per Unit & Supply Of 21mg/24hr Transdermal Patches (US$), March’2025
Figure 12-6: Nicoderm CQ - Recommended Dose & Treatment Schedule For Patients with Consumption More Than 10 Cigarette/Days (mg/day)
Figure 12-7: Oxybutynin Transdermal Patch - Approval Year By Region
Figure 12-8: Oxytrol - Price Per Unit & Supply In US (US$), March’2025
Figure 12-9: Kentera - Price Per Unit & Supply In UK (US$), February’2025
Figure 12-10: Sancuso - Approval Year By Region
Figure 12-11: US - Sancuso Patent Issue & Expiration Year
Figure 12-12: Allesaga - Price Per Unit By Dose (US$), February’2025
Figure 12-13: Allesaga - Initial & Maximum Recommended Dose (mg/hr)
Figure 12-14: Allesaga - Annual Sales (US$), 2020-2023
Figure 12-15: Tulo-Touch - Price Per Unit By Dose (US$), February’2025
Figure 12-16: Hokunalin - Price Per Unit By Dose (US$), February’2025
Figure 13-1: Global Transdermal Patch Market - Favorable Parameters
Figure 13-2: Global Transdermal Patch Market - Commercialization Challenges

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Companies Mentioned (Partial List)

A selection of companies mentioned in this report includes, but is not limited to:

AbbVie
Bayer HealthCare Pharmaceuticals
Corium International
Endo Pharmaceuticals
Hisamitsu Pharmaceutical
Luye Pharma
Noven Pharmaceuticals
Novartis
Purdue Pharma
Scilex Pharmaceuticals
Searchlight Pharma
Somerset Pharmaceuticals
Teikoku Seiyaku
Teva Pharmaceuticals
UCB
DURECT Corporation
Senju Pharmaceutical

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Global Transdermal Patch Market Opportunity, Patch Dosage, Price & Clinical Trials Insight 2030 Report Highlights & Findings:

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