Our body is not sterile and harbors enumerable microflora that are now being understood to play a complex role in immune regulation and shaping of the immune system in a continuous and dynamic way. In 8 chapters, Microbial Crosstalk with Immune System: New Insights in Therapeutics provides an overall introduction with special focus on how the immune system which is specifically geared to get rid of non-self-antigens, allows numerous microbes to colonize the human body. In the presence of microbes there are several observations that suggest that there are multiple roles that are played by these microbes in tumor progression and shaping of our immune system which is explained at length in subsequent chapters.
Microbial Crosstalk with Immune System: New Insights in Therapeutics discusses the emerging mechanisms of immune-therapeutics as well as its limitations while emphasizing the potential role of microbes in shaping immune-therapeutic and evolving novel strategies to deal with any limitations.
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Table of Contents
1. Introduction2. Significance of the Normal Microflora of the body
3. Immunological paradox for maintaining normal flora
4. Cancer prognosis and immune system
5. Microflora affects cancer progression/regression
6. Microflora impacts immune system
7. Therapeutics and microflora
8. Missing rungs in therapeutics and strategies to climb them
Authors
Asmita Das Assistant Professor, Department of Biotechnology, Delhi Technological University, Govt. of Delhi, NCT, Shahbad, India. Dr. Asmita Das completed her PhD from School of Life Sciences, Jawaharlal Nehru University and thereafter joined National Institute of Allergy and Infectious Diseases, National Institutes of Health, USA for a postdoctoral position for about 5 years.She has since been employed in Delhi Technological University since 2010 as Assistant Professor. Her research interests include Immunotherapeutics and Immunoinformatics. She is also involved in various interdisciplinary research. She has published several high impact peer reviewed papers including Immunity (IF: 21), Autophagy (IF: 11), Journal of Immunology (IF: 5.6) (top 10% articles in the journal in 2010) and many others. She serves on the editorial board of several peer reviewed journals. She has been actively involved in Industry- Academia partnership, including research guidance of industry personnel. She has served in several selection boards, external examiners and invited speakers in several institutes of repute.
