Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications provides a thorough discussion of the most state of the art material and polymer exploitations for the delivery of bioactive(s) as well as their current and clinical status. The book enables researchers to prepare a variety of smart drug delivery systems to investigate their properties as well as to discover their uses and applications. The novelty of this approach addresses an existing need of exhaustively understanding the potential of the materials including polymeric drug delivery systems that are smartly designed to deliver bioactive(s) into the body at targeted sites without showing side effects. The book is helpful for those in the health sector, specifically those developing nanomedicine using smart material-based nano-delivery systems. Polymers have unique co-operative properties that are not found with low-molecular-weight compounds along with their appealing physical and chemical properties, constituting the root of their success in drug delivery. Smart Polymeric Nano-Constructs in Drug Delivery: Concept, Design and Therapeutic Applications discusses smart and stimuli responsive polymers applicable in drug delivery, followed detailed information about various concepts and designing of polymeric novel drug delivery systems for treatment of various type of diseases, also discussing patents related to the field. The book helps readers to design and develop novel drug delivery systems based on smart materials for the effective delivery of bioactive that take advantage of recent advances in smart polymer-based strategies. It is useful to those in pharmaceutical sciences and related fields in developing new drug delivery systems.
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Table of Contents
1. Introduction to smart polymers and their applications2. Thermoresponsive polymers: Phase behaviour, drug delivery and biomedical applications
3. pH-sensitive polymeric nanocarriers for enhanced intracellular drug delivery
4. Photo-responsive nanocarriers for delivery of bioactives
5. Magnetically responsive polymer gels and elastomers for drug delivery
6. Bioadhesive and phase-change polymers for drug delivery
7. Block copolymer micelles as long-circulating drug vehicles
8. Polymer-drug conjugates: origins, progress to date and future directions
9. Molecularly imprinted polymers for drug delivery
10. Dendritic polymer macromolecular carriers for drug delivery
11. Hydrogels: from controlled release to pH-responsive drug delivery
12. Stimuli-responsive protein fibres for advanced applications
13. Smart drug delivery systems and its clinical potential
14. Novel biomimetic polymersomes as polymer therapeutics for drug delivery
15. Bioinspired Platform Conjugated systems for Active Drug Delivery
16. Electrically conductive polymers for drug delivery
17. Polymeric nanomedicine: Principles, Properties, and Regulatory Issues
18. Smart drug delivery systems and their clinical potential
19. Polymer-matrix nanocomposites and its potential applications
Authors
Suresh P Vyas Pioneer Scientist, Department of Pharmaceutical Sciences, India. Dr Vyas has over 36 years of teaching and research experience at postgraduate level. He is a pioneer scientist in the field of nano-biotechnology and immunology. He has over 325 research publications to his credit published in journals of high scientific impact and has authored 18 reference books including Pharmaceutical Biotechnology, Liposomal Therapeutics, Novel Controlled Drug Delivery Systems, Targeted Drug Delivery Systems, Theory and Practices in Novel Drug Delivery Systems. He is a commonwealth postdoctoral fellowship awardee and has worked under fellowship at School of Pharmacy University of London (U.K.). He is a recipient of Best Scientist award by Association of Pharmacy Professionals (APP) 2014 and many other honors. He serves on the editorial board of multiple international scientific publications including International Journal of Pharmaceutics (Elsevier). Udita Agrawal Associate Professor, Department of Pharmaceutical Sciences, Sagar (Madhya Pradesh) 470003, India. Dr. Agrawal has over 6 years of teaching and research experience at postgraduate level. She served as associate professor at Sagar Institute of Research and Technology Bhopal and Oriental College of Pharmacy Bhopal. She is Gold Medalist in B. Pharm and M. Pharm from Dr. H. S. Gour University and has been awarded with Pharmaceutical Science Alumi Award, Prof. C. S. Chauhan gold medal and Nagarjuna Award from Dr. H. S. Gour University Sagar (MP). She has received various awards in the field of drug delivery for her outstanding innovative research work including M. P Young Scientist Award 2016, Adina Young Scientist Award 2016 in the field of pharmaceutical and medical sciences and many best poster and oral presentation awards. She has more than 40 publications and book chapters in journals of international repute. She is currently working on targeted drug and peptides delivery systems exploiting polymers and nanobiotechnology. Rajeev Sharma Assistant Professor, Amity institute of Pharmacy, Amity University, Gwalior, Madhya Pradesh, India.Dr. Sharma earned his B. Pharm, M. Pharm and Ph.D. form Pharmaceutical Sciences, Dr. H. S. Gour Central University, Sagar, India. As Assistant Professor, he served in academia at Guru Ramdas Khalsa institute of Science and Technology Jabalpur (M.P.). He has the past experience as Junior research fellow-AICTE, ICMR-SRF and CSIR- research associate during his academic career and currently, working as an assistant manager in biologicals research and development division. He has edited 1 international book Nano Drug Delivery Strategies for the Treatment of Cancers and he published dozens of publications and book chapters. His current research interests are nanocarriers based targeted approach for the effective delivery of bioactives.
