Frontiers in Stem Cell and Regenerative Medicine Research: Volume 11

Table of Contents

CONTENTS

PREFACE

LIST OF CONTRIBUTORS

CHAPTER 1 AN INTRODUCTION TO THE USE OF EMBRYOLOGY IN CLINICAL PRACTICE

• Mandana Beigi Boroujeni, Seyyed Amir Yasin Ahmadi, Ali Fouladi Nashta and Fataneh Ghafari

INTRODUCTION

• Definitions

CHAPTER OBJECTIVES

CLINICAL APPLICATIONS FOR PHYSICIANS

• Infertility
• Perinatal Care
• Abnormalities and Congenital Defects
• Developmental Approach and Cell Therapy
• Molecular Approach and Personalized Medicine

RESEARCH HORIZONS

CONCLUSION

REFERENCES

CHAPTER 2 TISSUE DEVELOPMENT: MOLECULAR REGULATION AND SIGNALING TRANSDUCTION (FROM GENE TO HUMAN)

• Seyyed Amir Yasin Ahmadi, Nasim Beigi Boroujeni, Ali Fouladi Nashta, Fataneh Ghafari and Mandana Beigi Boroujeni

INTRODUCTION

• Definitions

CHAPTER OBJECTIVES

FROM GENE TO PROTEIN

• At Genome Level
• At Transcriptome Level
• At Proteome Level

FROM PROTEIN TO TISSUE AND HUMAN

• Paracrine Signaling
• Juxtacrine Signaling

EPIGENETICS IN REGULATION OF GENE EXPRESSION

CLINICAL AND RESEARCH HORIZONS

• In Perinatology
• In Infertility
• In Developmental Disorders
• In Stem Cell Research and Cell Therapy
• In Personalized Medicine
• Other Research Uses

CONCLUSION

REFERENCES

CHAPTER 3 CELL DIFFERENTIATION ON HYDROGELS AND ITS APPLICATION IN REGENERATIVE MEDICINE

• Maria I. León-Campos, Jesús A. Claudio-Rizo, Luis E. Cobos-Puc and Denis A. Cabrera-Munguia

INTRODUCTION

FUNDAMENTALS OF CELL DIFFERENTIATION

• Stem Cells in Regenerative Medicine
• Cell and Extracellular Matrix (ECM) Interactions in Tissue Regeneration

HYDROGELS USED IN REGENERATIVE MEDICINE

• Regenerative Medicine
• Main Studies in Regenerative Medicine Applying Hydrogels

HYDROGELS FOR CELL DIFFERENTIATION AND REGENERATIVE MEDICINE

• Suitable Properties of Hydrogels for Cell Differentiation
• Biophysical Properties
• Biochemical Properties
• Cell Therapy in Regenerative Medicine

PERSPECTIVES AND CHALLENGES OF HYDROGELS IN REGENERATIVE MEDICINE

CONCLUSION

REFERENCES

CHAPTER 4 THE PROMISING TREATMENT OF SEPSIS: STEM CELL THERAPY

• Zeynep Ture, Gokcen Dinc and Emine Alp

INTRODUCTION

• Sepsis Epidemiology
• Causative Microorganisms and Risk Factors in Sepsis
• The Role of the Immune Response in Sepsis
• The Management of Sepsis
• The Current Treatment Trends in Sepsis
• Mesenchymal Stem Cells
• Interferon-gamma
• Granulocyte-macrophage Colony-stimulating Factor (GM-CSF)
• Interleukin-7
• Immunoglobulin
• Thymosin Alpha1 (Tα1)

CONCLUSION

LIST OF ABBREVIATIONS

REFERENCES

CHAPTER 5 FIRST, DO NO HARM: CURRENT APPROACHES TO ASSESS TUMORIGENICITY IN STEM CELL-DERIVED THERAPEUTIC PRODUCTS

• Zongjie Wang

INTRODUCTION

• Tumorigenicity: How much and How Long
• Current Approaches
• Animal Model
• PCR
• Cytometry
• Soft Agar
• Outlook

CONCLUSION

CONFLICT OF INTEREST

ACKNOWLEDGEMENTS

REFERENCES

SUBJECT INDEX

Author

• Shazia Anjum