Visceral and Ectopic Fat. Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease

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Book
November 2022
Elsevier Science and Technology
ID: 5576523

While the health consequences and mechanisms by which visceral fat causes disease are well-studied, relatively less is known about ectopic fat, its patterns of deposition and its effects on the pathoetiology of type 2 diabetes, atherosclerosis, and cardiovascular disease. Visceral and Ectopic Fat: Risk Factors for Type 2 Diabetes, Atherosclerosis, and Cardiovascular Disease covers the wealth of literature that has been amassed over the past decade on this topic. This reference brings all the research and clinical data together in one volume and helps clinicians and academic researchers understand more thoroughly the underlying mechanisms and interrelation between fat depots and ectopic fat stores in relation to health and disease. It showcases some of the recent developments in adipose tissue biology, particularly on the impact of interventional strategies - bariatric surgery, liposuction, physical and dietary intervention - of which information is desired among health specialists and policy makers.

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Part I: Fat Stores
1. Obesity/VAT/SAT/Sex specific
2. Obesity and fat distribution in children and adolescents
3. Brown Adipose Tissue
4. Pericardial and peri-coronary fat

Part II: Ectopic fat stores
5. Noninvasive profiling of ectopic lipids
6. Flexibility of ectopic lipids
7. Liver
8. Myocardial Lipids Techniques and Applications of Proton Magnetic Resonance Spectroscopy of the Human Heart
9. Pancreas ectopic fat: imaging-based quantification
10. Ectopic fat accumulation around and within the kidney
11. Skeletal muscle
12. Bone marrow adipose tissue

Part III: Regulation of fat stores
13. Endocrinological pathways
14. The role of inflammation of fat tissue in relation to obesitas

Part IV: Clinical Aspects
15. Role of adipose tissue remodelling in diabetic heart disease
16. Cardiovascular Disease 17. Obesity in Relation to Cardiorenal function
18. Lung/Asthma
19. Brain Atrophy

Part V: Interventions
20. The impact of Very Low-Calorie Diets on ectopic fat deposition
21. Intermittent Fasting
22. Exercise
23. Combined Lifestyle Intervention
24. Medical Therapy
25. Gastric Volume Reduction
26. Gastric Bypass
27. Fecal Transplant

Authors

Hildo J. Lamb Professor of Radiology and Director of Cardiovascular Imaging, Leiden University Medical Center, The Netherlands. Prof. dr. Hildo J. Lamb MD, PhD is Professor of Radiology and Director of Cardiovascular Imaging at Leiden University Medical Center, The Netherlands. His clinical focus is on cardiovascular radiology, thoracic radiology, mammography, and pediatric radiology. His main research focus is currently on diseases related to obesity and diabetes mellitus. He is actively involved in scientific research in the field of non-invasive cardiovascular and body imaging, focusing on development of cardiovascular imaging techniques with fast conversion to clinical application, including 3D imaging, fast acquisition techniques and MR spectroscopy. He is a member of the Dutch scientific council for medical specialists (FMS), board member of the Dutch council for healthcare evaluation program, Dutch representative in the UEMS (European Union of Medical Specialists) section Radiology and member of the scientific board of the ESR. He is deputy editor of cardiovascular imaging for JMRI and a member of the cardiovascular scientific program committee for RSNA.

Table of Contents

Authors

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