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Metagenomics. Perspectives, Methods, and Applications. Edition No. 2

  • Book

  • December 2024
  • Elsevier Science and Technology
  • ID: 5576570

Metagenomics: Perspectives, Methods, and Applications, second edition, provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments and clinical settings. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians, and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case study-based application chapters include topics ranging from metagenome tools, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. This new edition has been fully updated to address the rapid growth and development of metagenomics applications, featuring expert discussion of recent developments and fresh case studies. Newly added chapters instruct in methods and implications of metagenomics in areas of growing focus, such as microbiome research, clinical diagnosis, metagenomic epidemiology, and plant microbe interaction. Data analysis is explained in simple terms for effective use of computational tools, software, and sequencing pipelines.

Table of Contents

  1. Metagenomics: A Paradigm Shift in Microbiology
  2. Metagenomic Protocols and Strategies
  3. Strategies for Taxonomic and Functional Annotation of
  4. Computational and Statistical Considerations in the Analysis of Metagenomic Data
  5. Data Science to Biologists: Insights into Microbiomics
  6. Meta-Omic and Machine Learning Approaches to Understand Microbial Cross Talks
  7. Measuring Microbiome Diversity and Diversity-Scaling Analysis with Hill Numbers
  8. 16S rRNA-Based Taxonomy Profiling in the Metagenomics
  9. Metagenomics and Neurodegenerative Diseases
  10. Metagenomic Guided Reengineering of Gut Microbiome with Specific Emphasis on Gastrointestinal Disorders
  11. Metagenomics: Implications in Oral Health and Disease
  12. Exploring Microbiome-Based Interventions in Periodontitis: The Role of Prebiotics and Postbiotics in Oral Health Management
  13. Understanding the Resistome of the Human Microbiome: A Metagenomic Approach
  14. SARS-CoV-2 and Genetic Variants: Alternative Therapies to Avert COVID-19 Pandemic
  15. AMR Surveillance in Bacteria Using Metagenomics
  16. An Overview of the Metagenomics-Based Assessment of Ecosystem Toxicology
  17. Metagenomic Approaches to Analyse Earthworm-Microbial Interactions to Maintain Sustainable Agroecosystem
  18. Plant Health in the Era of Metagenomics: Current State and Future Prospects
  19. The Agave and Cacti Microbiome: Models for a Planet Under Global Warming
  20. Marine Invertebrate Microbe Interactions: An Insight into Immunogenomics Through Metagenomic Approach
  21. Advances of Functional Metagenomics in Harnessing Thermozymes

Authors

Muniyandi Nagarajan Assistant Professor, Department of Genomic Science, School of Biological Science, Central University of Kerala, Kerala, India. Dr. M. Nagarajan is an Associate Professor, at Department of Genomic Science, School of Biological Science, Central University of Kerala, Kasaragod, Kerala, India. His research interests primarily focus on population genetics, functional genomics and microbiome of wild and domestic animals. He received his M.Sc and PhD in Environmental Biotechnology from Manonmaniam Sundaranar University, Tirunelveli, Tamil Nadu, India. After his Ph.D, he carried out his postdoctoral research at Centre for Cellular and Molecular Biology (CCMB), Hyderabad, India and then at Laboratoire de Biologie Mol�culaire de la Cellule, Ecole Normale Sup�rieure de Lyon, France. He was an Assistant Professor at Sri Paramakalyani Centre for Environmental Sciences, Manonmaniam Sundaranar University, Alwarkurichi, Tamil Nadu before joining Central University of Kerala in 2012. He is an editorial board member of Scientific Reports, BMC Genomics, PLoS One, Frontiers in Genetics, and Frontiers in Ecology and Evolution. He is a member of ISAG-FAO Advisory Group on Animal Genetic Diversity. He has more than 40 publications in leading international journals including PLoS Genetics and Molecular Ecology.