Diabetic Retinopathy Market Size, Share & Industry Trends Analysis Report By Type, By Treatment Type, By Regional Outlook and Forecast, 2021-2027

The Global Diabetic Retinopathy Market size is expected to reach $7.7 billion by 2027, rising at a market growth of 11.3% CAGR during the forecast period.



Diabetic retinopathy is a critical medical disorder that affects the eyes as a result of diabetes or inefficient insulin level in the blood of the patient. Impairment to blood vessels of the light-sensitive tissue of the retina is the main cause of diabetic retinopathy. In addition, blurred vision, dark or empty spots in the vision, fluctuating vision, poor color identification, and vision loss are the most typical symptoms of this disorder. A high sugar level in the blood causes blockage of the retina's small blood capillaries, impeding blood flow. Advanced cases of diabetic retinopathy require laser therapy or surgical operations. Mild-to-moderate instances of diabetic retinopathy can be cured with appropriate diabetes management.

Diabetic retinopathy may cause no symptoms or just minor vision abnormalities in the initial stages, however, it can result in blindness in advance stages. Anyone with type 1 or type 2 diabetes can develop the illness. The longer a person has diabetes, the more likely they are to develop ocular complications due to poorly regulated blood sugar levels. Diabetic retinopathy can progress to diabetic retinal detachment, macular edema, and neovascular glaucoma, among other serious eye disorders.

Diabetic retinopathy can also mutate to proliferative diabetic retinopathy, which is a more severe form of the disorder. Affected blood vessels close off in this type, leading the retina to develop new, dysfunctional blood vessels. These new blood vessels are fragile, and they may leak into the clear, jellylike fluid that fills the center of the eye of the patient. Non-proliferative diabetic retinopathy, NPDR, is a kind of diabetic retinopathy in which symptoms are minimal or absent. New blood vessels are weakened or stop forming in this more prevalent form of diabetic retinopathy. The membranes of the blood vessels in the retina deteriorate when a patient suffers NPDR. Small bulges emerge from the smaller vessels' walls, occasionally blood and seeping fluid into the retina. Larger retinal vessels may also begin to dilate and their size becomes irregular.

COVID-19 Impact Analysis

The COVID-19 pandemic caused a severe impact to various economies all over the world. Several businesses were significantly devastated as a result of the outbreak of the COVID-19 infection. In addition, the governments of several countries were forced to impose lockdowns in their nations. As a result, the manufacturing units of numerous goods were temporarily shut. Moreover, these lockdowns also caused a major disruption in the supply chain of various goods. Further, the COVID-19 led the worldwide healthcare industry to a significant failure due to the shortage of beds and oxygen in hospitals. The outbreak of COVID-19 all over the world has placed healthcare workflows in a disarray. Various industries, including numerous sub-domains of healthcare, have been forced to temporarily close their units because of the rising cases of infection.

Market driving Factors:

Rising number of diabetic patients

Diabetes is considered as the major origin of diabetic retinopathy. Therefore, an increase in the number of patients that are suffering from diabetes is expected to directly increase the demand for diabetic retinopathy treatments. In addition, there is a significant rise in the number of patients with diabetes, due to which, the requirement of diabetic retinopathy treatment is continuously increasing. There is a significant number of people that are concerned about the damage that can be caused to their eyes by the occurrence of the diabetic retinopathy. The diabetic retinopathy market is expected to grow due to an increase in diabetes prevalence around the world. According to the National Center for Biotechnology Information, Diabetic retinopathy affected 126 million people in 2010, and it is expected to affect more than 191 million people by 2030.

Increasing geriatric population all over the world

Instances of the diabetic retinopathy are more common in geriatric people. The prevalence of this disorder is found to be more robust in people that are aging above 60. Moreover, the number of elderly people is becoming significant and accounts for a substantial share of the population in nearly every country, affecting several aspects of society, including financial markets and labor, demand for goods and services, like housing, transportation, as well as social protection, along with family structures and intergenerational ties. According to the United Nations Organization, the population of elderly people all over the world is expected to become more than double throughout the next three decades, reaching 1.5 billion by 2050.

Marketing Restraining Factor:

Lack of healthcare facilities in developing and under-developed economies

People residing in poor countries have lesser access to healthcare facilities than wealthy people, while the poor people have lesser access to healthcare services inside their own countries. In contrast, poor people in low- and Middle-income countries, or LMICs, are continuously disadvantaged in several aspects of access as well as their determinants. Moreover, the healthcare sector in the least developed countries is poorly underfunded, and a vast majority of these countries are unable to provide basic and fundamental healthcare services to their citizens. This problem is most prevalent in under-developed and developing countries, where government's investments on public security is increasing at the cost of healthcare expenditure.

Type Outlook

Based on Type, the market is segmented into Proliferative and Diabetic Macular Edema (DME). In 2020, the diabetic macular edema segment witnessed a substantial revenue share of the diabetic retinopathy market. Diabetic macular edema, or DME, is an eye disorder that can affect people with type 1 as well as type 2 diabetes. High blood sugar levels that persist over time due to inadequate glucose regulation can harm small blood vessels inside the body, including the eyes. Diabetic retinopathy is a disorder that causes vision loss by damaging the blood vessels inside the retina. Fluid can leak into the fovea, which is the area of the eye where acute, straight-ahead vision occurs if left untreated. The fluid causes the macula to swell, causing vision to become blurry.

Treatment Type Outlook

Based on Treatment Type, the market is segmented into Anti VEGF Drug, Steroid Implants, Laser Surgeries, and Vitrectomy. In 2020, the anti VEGF drugs segment procured the largest revenue share of the diabetic retinopathy market. Anti-VEGF medications are a class of drugs that prevent the growth of new blood vessel and edema. These medications can be used to treat a variety of eye disorders that produce new blood vessel growth or swelling underneath the macular area of the retina. The rising growth of this segment is owing to the reliability and effectiveness of this class of drugs. A significant number of healthcare facilities are leveraging these drugs in order to treat diabetic retinopathy.

Regional Outlook

Based on Regions, the market is segmented into North America, Europe, Asia Pacific, and Latin America, Middle East & Africa. In 2020, North America procured the largest revenue share of the diabetic retinopathy market. The increasing growth of this segment is attributed to the higher and rapidly increasing frequency of diabetic retinopathy in this region, combined with well-established healthcare infrastructure along with increasing government measures to raise awareness. These government initiatives is expected to make it easier for people to get examined for diabetic retinopathy. Moreover, North America is one of the most advanced regions in terms of technology. The adoption of various latest cutting-edge technologies across the region is increasing in several sectors in the region.

The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Allergan PLC (Abbvie, Inc.), Bayer AG, Alimera Sciences, Inc., Novartis AG, Pfizer, Inc., F-Hoffmann-La Roche Ltd., Ampio Pharmaceuticals-us, KOWA CO., LTD., Regeneron Pharmaceuticals, Inc., and Bausch Health Companies, Inc.

• Feb 2022: Alimera Sciences expanded its geographical footprint in Spain with the launch of ILUVIEN. Through this geographical expansion, the company aimed to provide treatment for non-infectious posterior uveitis to its customers across Spain.
• Jan 2022: Roche received the US FDA approval for Vabysmo. The new product aimed to treat neovascular or wet age-related macular degeneration along with diabetic macular edema.
• Oct 2021: Roche got the US FDA approval for its Susvimo 100 mg/mL. The new product is expected to be available for intravitreal use through the ocular implant for the diagnosis of patients with neovascular or wet age-related macular degeneration.
• Oct 2021: Bausch along with Lomb and Clearside Biomedical received the US FDA approval for XIPERE. The new product is expected to be available for suprachoroidal use in order to treat macular edema related to uveitis.
• Sep 2021: AbbVie partnered with REGENXBIO, a leading clinical-stage biotechnology company. Following this partnership, the companies is expected to jointly develop and commercialize RGX-314 intending to offer a potential one-time gene therapy to cure diabetic retinopathy, wet age-related macular degeneration, and other chronic retinal disorders.
• May 2021: Bausch came into a strategic multi-year agreement with SIFI, a leader in international ophthalmic. Following this agreement, Bausch is expected to support SIFI in commercializing its innovative products for the treatment of ophthalmic disorders across Russia.
• Apr 2021: Alimera Sciences entered into an exclusive license agreement with Ocumension Therapeutics, a Chinese ophthalmology platform company. Following this acquisition, Alimera is expected to deliver Alimera's 0.19mg fluocinolone acetonide intravitreal implant to Ocumension in order to focus on its vision geographic expansion.
• Mar 2021: Roche signed a multi-year research collaboration and licensing agreement with SemaThera, a biotechnology company. This collaboration aimed to develop a new lineup of biologicals under the umbrella of SemaThera to treat diabetic retinopathy as well as other ischemic retinal diseases.
• Dec 2020: Alimera Sciences expanded its geographical footprint with the launch of ILUVIEN in the Netherlands. This geographical expansion is expected to complement the company's strategy to avail ILUVIEN to more patients and physicians in various geographies.
• Sep 2020: Alimera Sciences entered into a distribution agreement with Medis Pharmaceutical Company, the largest India-based Pharmaceutical Company. Through this agreement, Alimera aimed to expand its geographical footprint in the Czech Republic and Austria with the launch of ILUVIEN in the countries.
• Sep 2020: Bayer received Drugs Controller General of India approval for its novel indication for intravitreal Aflibercept injection solution. This approval aimed to accelerate the treatment of Diabetic Macular Edema with a new injection solution, which is available for intravitreal use in India.
• May 2019: Regeneron Pharmaceuticals received the US FDA approval for EYLEA injection. The new product is expected to be leveraged for the treatment of all stages of diabetic retinopathy to minimize the risk of blindness.

Scope of the Study

Market Segments Covered in the Report:

By Type

• Proliferative
• Diabetic Macular Edema (DME)

By Treatment Type

• Anti VEGF Drug
• Steroid Implants
• Laser Surgeries
• Vitrectomy

By Geography

• North America
• US
• Canada
• Mexico
• Rest of North America
• Europe
• Germany
• UK
• France
• Russia
• Spain
• Italy
• Rest of Europe
• Asia Pacific
• China
• Japan
• India
• South Korea
• Singapore
• Malaysia
• Rest of Asia Pacific
• LAMEA
• Brazil
• Argentina
• UAE
• Saudi Arabia
• South Africa
• Nigeria
• Rest of LAMEA

Key Market Players

List of Companies Profiled in the Report:

• Allergan PLC (Abbvie, Inc.)
• Bayer AG
• Alimera Sciences, Inc.
• Novartis AG
• Pfizer, Inc.
• F-Hoffmann-La Roche Ltd.
• Ampio Pharmaceuticals-us
• KOWA CO., LTD.
• Regeneron Pharmaceuticals, Inc.
• Bausch Health Companies, Inc.

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