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In Vitro Toxicity Testing Market Size, Share & Industry Trends Analysis Report By Type (Absorption, Toxic Substances, and Dose), By Technology, By End User, By Regional Outlook and Forecast, 2022-2028

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    Report

  • 209 Pages
  • April 2022
  • Region: Global
  • Marqual IT Solutions Pvt. Ltd (KBV Research)
  • ID: 5600856
Description Jump to:
The Global In Vitro Toxicity Testing Market size is expected to reach $37.5 billion by 2028, rising at a market growth of 10.8% CAGR during the forecast period.

The term "in vitro" refers to a method for testing dangerous compounds on a section of an organism that has been isolated. It is used to identify dangerous chemical chemicals and to detect toxicity in new goods such as cosmetics, pharmaceuticals, and food additives at an early stage of development. In vitro toxicity testing (IVTT) is generally used in medication development to assess the safety and to evaluate compounds as per their effectiveness.

In vitro toxicity testing can also be used to assess a drug's absorption, distribution, metabolism, and excretion (ADME), dosage response, and threshold response. The in vitro toxicology testing market is expected to expand due to an increase in demand for in vitro toxicity testing in several industries such as chemicals, pharmaceuticals, and food. Furthermore, the market for in vitro toxicity testing is increasing due to increased awareness of examining different cosmetics, foods, and other items.

In-vitro testing is a cost-effective and time-saving method of determining toxicity. Rapid advancements in biomedical sciences are expected to lead to the development of newer and more advanced in-vitro test methodologies for hazard characterization. Toxicity testing is gradually improving, with the help of much new technology. It is currently well-positioned to benefit from promising biotechnology revolutions.

Computational toxicology, Bioinformatics, epigenetics, and other modifications in toxicity testing methodologies have the potential to alter the paradigm away from whole-animal testing and toward in-vitro methods that examine changes employing cell lines as well as other biological components in a variety of processes. A variety of new domains and methodologies are revealing important new information about biological responses to substances in human tissues. During the projected period, these advancements are expected to propel the in-vitro toxicology market ahead.



COVID-19 Impact Analysis

Many enterprises in vitro toxicity testing industry were compelled to temporarily halt activities due to the COVID-19 pandemic, to ensure compliance with new government rules aimed at preventing the disease's spread. This halt in operations has a direct impact in vitro toxicity testing market's revenue flow. In addition, due to a scarcity of raw materials and people during the lockdown, the production of industrial products came to a halt. Furthermore, enterprises in this industry do not get any fresh consignments. As a result, the in vitro toxicity testing market has been negatively impacted by the suspension of industrial activity and lockdowns for several months.

Market Growth Factors


Drug discovery and personalized therapy

The pharmaceutical industry's productivity has decreased in recent years as development cost has increased and the profitability of newly launched medical entities (NMEs) has decreased. The malfunction of encouraging new drug applicants due to the negative impact revealed throughout animal experimental safety studies and clinical is one of the biggest challenges facing the pharmaceutical industry. Before pharmaceuticals enter clinical trials, strategies to demonstrate or anticipate effectiveness and safety in people could dramatically reduce the failures rate of new therapies. Personalized medications and drug discovery using in vitro approaches have received more attention.

Techniques usage in cosmetic industry

Testing a product designed for human use on the skin surface is the most intelligent method to do it. In vitro testing can be done with human hair follicles, human primary skin cells, human reconstructed epidermis, or human skin explants. In vitro testing procedures based on rebuilt human cells or skin can yield results in a couple of days or weeks. Animal testing, on the other hand, can take months. In vitro testing allows evaluating and validating the mechanism of action of cosmetics components or solutions at the cellular and molecular levels. This is a great technique to back up an inventive idea and a patent application. In vitro testing has grown in popularity as a result of widespread opposition to the death and suffering of lab animals. In vitro testing becomes increasingly important for the cosmetics business as more countries and consumers abandon animal testing.

Marketing Restraining Factor:


Regulatory authorities" reluctance and a scarcity of qualified professionals

Across a variety of industries, there has been a growing emphasis on the use of in vitro toxicity testing procedures. Validated alternative tests can be used instead of in vivo tests by regulatory agencies. In such cases, in vitro approaches must demonstrate their superiority in terms of safety and efficacy over animal methods. Even after the assay has demonstrated its superior scientific significance, several countries have indicated a reluctance to use in vitro testing over in vivo procedures. Animal testing data is still used by a range of regulatory authorities in the United States. For the evaluation of new toxicological test methods, many agencies employ in vivo methodologies.



Type Outlook

Based on Type, the market is segmented into Absorption, Toxic Substances, and Dose. The absorption segment procured the highest revenue share in the In Vitro Toxicity Testing Market in 2021. For instance, in vitro dermal absorption is a test that determines the behavior of a test substance when it is applied to the skin's surface. The skin specimen is positioned between two chambers of a diffusion cell (donor chamber and receptor chamber), which can be static or flow-through.

Technology Outlook

Based on Technology, the market is segmented into Cell Culture Technologies, High Throughput Technologies, and Toxicogenomics. The toxicgenomics segment recorded a significant revenue share in the In Vitro Toxicity Testing Market in 2021. It can give a collection of generalized expression profiles for many kinds of toxicity, enabling an unknown substance to be described depending on which profiles it matches. While genomics is widely utilized for linkage analysis and marker characterization, it has not yet been properly integrated into toxicity testing and risk assessment methodologies.

End User Outlook

Based on End User, the market is segmented into Cosmetics & Households Products, Pharmaceuticals Industry, Food Industry, Chemicals, and Industry. The cosmetics and households products segment acquired the largest revenue share in the In Vitro Toxicity Testing Market in 2021. In vitro testing has long been used as a substitute for animal testing, and recent technology advancements have enabled the cosmetics industry to use sophisticated yet cost-effective in vitro models. This is due to strict government regulations and the prohibition of animal testing, as well as perks such as cost-effectiveness, reduced time consumption, and improved toxin detection efficiency.

Regional Outlook

Based on Regions, the market is segmented into North America, Europe, Asia Pacific, and Latin America, Middle East & Africa. The North America segment acquired the largest revenue share in the In Vitro Toxicity Testing Market in 2021. Due to a greater focus on drug discovery by government agencies, and increase in healthcare spending, and the availability of suitable infrastructure for the development and growth of drug development technologies Furthermore, strict regulatory standards governing medication development and clearance have expanded the use of in-vitro toxicology testing services in the market sector. The demand for in-vitro toxicity testing is being propelled by biopharmaceutical firms" recurring introductions of biologics and bio similar pharmaceuticals in the United States.

The market research report covers the analysis of key stake holders of the market. Key companies profiled in the report include Thermo Fisher Scientific, Inc., General Electric (GE) Co., AstraZeneca PLC, Catalent, Inc., Laboratory Corporation of America Holdings, Acacia Pharma Group Plc, GlaxoSmithKline PLC, Helsinn Healthcare SA., and Heron Therapeutics, Inc.

Recent Strategies Deployed in In Vitro Toxicity Testing Market

  • 2021-Nov: Labcorp completed the acquisition of Toxikon, a contract research enterprise. This acquisition aimed to emphasise nonclinical development commitment and prior abilities for both medical device testing and drug development.
  • 2021-May: GE Healthcare took over Zionexa, a leading innovator of in-vivo oncology and neurology biomarkers. Through this acquisition, Zionexa is expected to propel the growth of its encouraging R&D pipeline along with its business footprint, while delivering Zionexa's employees’ access to global and integral expertise.

Scope of the Study


Market Segments Covered in the Report:


By Type
  • Absorption
  • Toxic Substances
  • Dose
By Technology
  • Cell Culture Technologies
  • High Throughput Technologies
  • Toxicogenomics
By End User
  • Cosmetics & amp; Households Products
  • Pharmaceuticals Industry
  • Food Industry
  • Chemicals Industry

By Geography

  • North America
  • US
  • Canada
  • Mexico
  • Rest of North America
  • Europe
  • Germany
  • UK
  • France
  • Russia
  • Spain
  • Italy
  • Rest of Europe
  • Asia Pacific
  • China
  • Japan
  • India
  • South Korea
  • Singapore
  • Malaysia
  • Rest of Asia Pacific
  • LAMEA
  • Brazil
  • Argentina
  • UAE
  • Saudi Arabia
  • South Africa
  • Nigeria
  • Rest of LAMEA

Key Market Players


List of Companies Profiled in the Report:

  • Thermo Fisher Scientific, Inc.
  • General Electric (GE) Co.
  • AstraZeneca PLC
  • Catalent, Inc.
  • Laboratory Corporation of America Holdings
  • Acacia Pharma Group Plc
  • GlaxoSmithKline PLC
  • Helsinn Healthcare SA.
  • Heron Therapeutics, Inc.

Unique Offerings from the Publisher

  • Exhaustive coverage
  • The highest number of market tables and figures
  • Subscription-based model available
  • Guaranteed best price
  • Assured post sales research support with 10% customization free

Table of Contents

Chapter 1. Market Scope & Methodology
1.1 Market Definition
1.2 Objectives
1.3 Market Scope
1.4 Segmentation
1.4.1 Global In Vitro Toxicity Testing Market, by Type
1.4.2 Global In Vitro Toxicity Testing Market, by Technology
1.4.3 Global In Vitro Toxicity Testing Market, by End User
1.4.4 Global In Vitro Toxicity Testing Market, by Geography
1.5 Methodology for the research
Chapter 2. Market Overview
2.1 Introduction
2.1.1 Overview
2.1.1.1 Market Composition and Scenario
2.2 Key Factors Impacting the Market
2.2.1 Market Drivers
2.2.2 Market Restraints
Chapter 3. Global In Vitro Toxicity Testing Market by Type
3.1 Global Absorption Market by Region
3.2 Global Toxic Substances Market by Region
3.3 Global Dose Market by Region
Chapter 4. Global In Vitro Toxicity Testing Market by Technology
4.1 Global Cell Culture Technologies Market by Region
4.2 Global High Throughput Technologies Market by Region
4.3 Global Toxicogenomics Market by Region
Chapter 5. Global In Vitro Toxicity Testing Market by End User
5.1 Global Cosmetics & Households Products Market by Region
5.2 Global Pharmaceuticals Industry Market by Region
5.3 Global Food Industry Market by Region
5.4 Global Chemicals Industry Market by Region
Chapter 6. Global In Vitro Toxicity Testing Market by Region
6.1 North America In Vitro Toxicity Testing Market
6.1.1 North America In Vitro Toxicity Testing Market by Type
6.1.1.1 North America Absorption Market by Country
6.1.1.2 North America Toxic Substances Market by Country
6.1.1.3 North America Dose Market by Country
6.1.2 North America In Vitro Toxicity Testing Market by Technology
6.1.2.1 North America Cell Culture Technologies Market by Country
6.1.2.2 North America High Throughput Technologies Market by Country
6.1.2.3 North America Toxicogenomics Market by Country
6.1.3 North America In Vitro Toxicity Testing Market by End User
6.1.3.1 North America Cosmetics & Households Products Market by Country
6.1.3.2 North America Pharmaceuticals Industry Market by Country
6.1.3.3 North America Food Industry Market by Country
6.1.3.4 North America Chemicals Industry Market by Country
6.1.4 North America In Vitro Toxicity Testing Market by Country
6.1.4.1 US In Vitro Toxicity Testing Market
6.1.4.1.1 US In Vitro Toxicity Testing Market by Type
6.1.4.1.2 US In Vitro Toxicity Testing Market by Technology
6.1.4.1.3 US In Vitro Toxicity Testing Market by End User
6.1.4.2 Canada In Vitro Toxicity Testing Market
6.1.4.2.1 Canada In Vitro Toxicity Testing Market by Type
6.1.4.2.2 Canada In Vitro Toxicity Testing Market by Technology
6.1.4.2.3 Canada In Vitro Toxicity Testing Market by End User
6.1.4.3 Mexico In Vitro Toxicity Testing Market
6.1.4.3.1 Mexico In Vitro Toxicity Testing Market by Type
6.1.4.3.2 Mexico In Vitro Toxicity Testing Market by Technology
6.1.4.3.3 Mexico In Vitro Toxicity Testing Market by End User
6.1.4.4 Rest of North America In Vitro Toxicity Testing Market
6.1.4.4.1 Rest of North America In Vitro Toxicity Testing Market by Type
6.1.4.4.2 Rest of North America In Vitro Toxicity Testing Market by Technology
6.1.4.4.3 Rest of North America In Vitro Toxicity Testing Market by End User
6.2 Europe In Vitro Toxicity Testing Market
6.2.1 Europe In Vitro Toxicity Testing Market by Type
6.2.1.1 Europe Absorption Market by Country
6.2.1.2 Europe Toxic Substances Market by Country
6.2.1.3 Europe Dose Market by Country
6.2.2 Europe In Vitro Toxicity Testing Market by Technology
6.2.2.1 Europe Cell Culture Technologies Market by Country
6.2.2.2 Europe High Throughput Technologies Market by Country
6.2.2.3 Europe Toxicogenomics Market by Country
6.2.3 Europe In Vitro Toxicity Testing Market by End User
6.2.3.1 Europe Cosmetics & Households Products Market by Country
6.2.3.2 Europe Pharmaceuticals Industry Market by Country
6.2.3.3 Europe Food Industry Market by Country
6.2.3.4 Europe Chemicals Industry Market by Country
6.2.4 Europe In Vitro Toxicity Testing Market by Country
6.2.4.1 Germany In Vitro Toxicity Testing Market
6.2.4.1.1 Germany In Vitro Toxicity Testing Market by Type
6.2.4.1.2 Germany In Vitro Toxicity Testing Market by Technology
6.2.4.1.3 Germany In Vitro Toxicity Testing Market by End User
6.2.4.2 UK In Vitro Toxicity Testing Market
6.2.4.2.1 UK In Vitro Toxicity Testing Market by Type
6.2.4.2.2 UK In Vitro Toxicity Testing Market by Technology
6.2.4.2.3 UK In Vitro Toxicity Testing Market by End User
6.2.4.3 France In Vitro Toxicity Testing Market
6.2.4.3.1 France In Vitro Toxicity Testing Market by Type
6.2.4.3.2 France In Vitro Toxicity Testing Market by Technology
6.2.4.3.3 France In Vitro Toxicity Testing Market by End User
6.2.4.4 Russia In Vitro Toxicity Testing Market
6.2.4.4.1 Russia In Vitro Toxicity Testing Market by Type
6.2.4.4.2 Russia In Vitro Toxicity Testing Market by Technology
6.2.4.4.3 Russia In Vitro Toxicity Testing Market by End User
6.2.4.5 Spain In Vitro Toxicity Testing Market
6.2.4.5.1 Spain In Vitro Toxicity Testing Market by Type
6.2.4.5.2 Spain In Vitro Toxicity Testing Market by Technology
6.2.4.5.3 Spain In Vitro Toxicity Testing Market by End User
6.2.4.6 Italy In Vitro Toxicity Testing Market
6.2.4.6.1 Italy In Vitro Toxicity Testing Market by Type
6.2.4.6.2 Italy In Vitro Toxicity Testing Market by Technology
6.2.4.6.3 Italy In Vitro Toxicity Testing Market by End User
6.2.4.7 Rest of Europe In Vitro Toxicity Testing Market
6.2.4.7.1 Rest of Europe In Vitro Toxicity Testing Market by Type
6.2.4.7.2 Rest of Europe In Vitro Toxicity Testing Market by Technology
6.2.4.7.3 Rest of Europe In Vitro Toxicity Testing Market by End User
6.3 Asia Pacific In Vitro Toxicity Testing Market
6.3.1 Asia Pacific In Vitro Toxicity Testing Market by Type
6.3.1.1 Asia Pacific Absorption Market by Country
6.3.1.2 Asia Pacific Toxic Substances Market by Country
6.3.1.3 Asia Pacific Dose Market by Country
6.3.2 Asia Pacific In Vitro Toxicity Testing Market by Technology
6.3.2.1 Asia Pacific Cell Culture Technologies Market by Country
6.3.2.2 Asia Pacific High Throughput Technologies Market by Country
6.3.2.3 Asia Pacific Toxicogenomics Market by Country
6.3.3 Asia Pacific In Vitro Toxicity Testing Market by End User
6.3.3.1 Asia Pacific Cosmetics & Households Products Market by Country
6.3.3.2 Asia Pacific Pharmaceuticals Industry Market by Country
6.3.3.3 Asia Pacific Food Industry Market by Country
6.3.3.4 Asia Pacific Chemicals Industry Market by Country
6.3.4 Asia Pacific In Vitro Toxicity Testing Market by Country
6.3.4.1 China In Vitro Toxicity Testing Market
6.3.4.1.1 China In Vitro Toxicity Testing Market by Type
6.3.4.1.2 China In Vitro Toxicity Testing Market by Technology
6.3.4.1.3 China In Vitro Toxicity Testing Market by End User
6.3.4.2 Japan In Vitro Toxicity Testing Market
6.3.4.2.1 Japan In Vitro Toxicity Testing Market by Type
6.3.4.2.2 Japan In Vitro Toxicity Testing Market by Technology
6.3.4.2.3 Japan In Vitro Toxicity Testing Market by End User
6.3.4.3 India In Vitro Toxicity Testing Market
6.3.4.3.1 India In Vitro Toxicity Testing Market by Type
6.3.4.3.2 India In Vitro Toxicity Testing Market by Technology
6.3.4.3.3 India In Vitro Toxicity Testing Market by End User
6.3.4.4 South Korea In Vitro Toxicity Testing Market
6.3.4.4.1 South Korea In Vitro Toxicity Testing Market by Type
6.3.4.4.2 South Korea In Vitro Toxicity Testing Market by Technology
6.3.4.4.3 South Korea In Vitro Toxicity Testing Market by End User
6.3.4.5 Singapore In Vitro Toxicity Testing Market
6.3.4.5.1 Singapore In Vitro Toxicity Testing Market by Type
6.3.4.5.2 Singapore In Vitro Toxicity Testing Market by Technology
6.3.4.5.3 Singapore In Vitro Toxicity Testing Market by End User
6.3.4.6 Malaysia In Vitro Toxicity Testing Market
6.3.4.6.1 Malaysia In Vitro Toxicity Testing Market by Type
6.3.4.6.2 Malaysia In Vitro Toxicity Testing Market by Technology
6.3.4.6.3 Malaysia In Vitro Toxicity Testing Market by End User
6.3.4.7 Rest of Asia Pacific In Vitro Toxicity Testing Market
6.3.4.7.1 Rest of Asia Pacific In Vitro Toxicity Testing Market by Type
6.3.4.7.2 Rest of Asia Pacific In Vitro Toxicity Testing Market by Technology
6.3.4.7.3 Rest of Asia Pacific In Vitro Toxicity Testing Market by End User
6.4 LAMEA In Vitro Toxicity Testing Market
6.4.1 LAMEA In Vitro Toxicity Testing Market by Type
6.4.1.1 LAMEA Absorption Market by Country
6.4.1.2 LAMEA Toxic Substances Market by Country
6.4.1.3 LAMEA Dose Market by Country
6.4.2 LAMEA In Vitro Toxicity Testing Market by Technology
6.4.2.1 LAMEA Cell Culture Technologies Market by Country
6.4.2.2 LAMEA High Throughput Technologies Market by Country
6.4.2.3 LAMEA Toxicogenomics Market by Country
6.4.3 LAMEA In Vitro Toxicity Testing Market by End User
6.4.3.1 LAMEA Cosmetics & Households Products Market by Country
6.4.3.2 LAMEA Pharmaceuticals Industry Market by Country
6.4.3.3 LAMEA Food Industry Market by Country
6.4.3.4 LAMEA Chemicals Industry Market by Country
6.4.4 LAMEA In Vitro Toxicity Testing Market by Country
6.4.4.1 Brazil In Vitro Toxicity Testing Market
6.4.4.1.1 Brazil In Vitro Toxicity Testing Market by Type
6.4.4.1.2 Brazil In Vitro Toxicity Testing Market by Technology
6.4.4.1.3 Brazil In Vitro Toxicity Testing Market by End User
6.4.4.2 Argentina In Vitro Toxicity Testing Market
6.4.4.2.1 Argentina In Vitro Toxicity Testing Market by Type
6.4.4.2.2 Argentina In Vitro Toxicity Testing Market by Technology
6.4.4.2.3 Argentina In Vitro Toxicity Testing Market by End User
6.4.4.3 UAE In Vitro Toxicity Testing Market
6.4.4.3.1 UAE In Vitro Toxicity Testing Market by Type
6.4.4.3.2 UAE In Vitro Toxicity Testing Market by Technology
6.4.4.3.3 UAE In Vitro Toxicity Testing Market by End User
6.4.4.4 Saudi Arabia In Vitro Toxicity Testing Market
6.4.4.4.1 Saudi Arabia In Vitro Toxicity Testing Market by Type
6.4.4.4.2 Saudi Arabia In Vitro Toxicity Testing Market by Technology
6.4.4.4.3 Saudi Arabia In Vitro Toxicity Testing Market by End User
6.4.4.5 South Africa In Vitro Toxicity Testing Market
6.4.4.5.1 South Africa In Vitro Toxicity Testing Market by Type
6.4.4.5.2 South Africa In Vitro Toxicity Testing Market by Technology
6.4.4.5.3 South Africa In Vitro Toxicity Testing Market by End User
6.4.4.6 Nigeria In Vitro Toxicity Testing Market
6.4.4.6.1 Nigeria In Vitro Toxicity Testing Market by Type
6.4.4.6.2 Nigeria In Vitro Toxicity Testing Market by Technology
6.4.4.6.3 Nigeria In Vitro Toxicity Testing Market by End User
6.4.4.7 Rest of LAMEA In Vitro Toxicity Testing Market
6.4.4.7.1 Rest of LAMEA In Vitro Toxicity Testing Market by Type
6.4.4.7.2 Rest of LAMEA In Vitro Toxicity Testing Market by Technology
6.4.4.7.3 Rest of LAMEA In Vitro Toxicity Testing Market by End User
Chapter 7. Company Profiles
7.1 Thermo Fisher Scientific, Inc.
7.1.1 Company Overview
7.1.2 Financial Analysis
7.1.3 Segmental and Regional Analysis
7.1.4 Research & Development Expense
7.1.5 SWOT Analysis
7.2 General Electric (GE) Co.
7.2.1 Company Overview
7.2.2 Financial Analysis
7.2.3 Segmental and Regional Analysis
7.2.4 Research & Development Expense
7.2.5 Recent strategies and developments:
7.2.5.1 Acquisition and Mergers:
7.2.6 SWOT Analysis
7.3 AstraZeneca PLC
7.3.1 Company Overview
7.3.2 Financial Analysis
7.3.3 Regional Analysis
7.3.4 Research & Development Expenses
7.4 Catalent, Inc.
7.4.1 Company Overview
7.4.2 Financial Analysis
7.4.3 Regional & Segmental Analysis
7.4.4 Research & Development Expenses
7.5 Laboratory Corporation of America Holdings (Covance, Inc.)
7.5.1 Company Overview
7.5.2 Financial Analysis
7.5.3 Segmental and Regional Analysis
7.5.4 Recent strategies and developments:
7.5.4.1 Acquisition and Mergers:
7.6 Acacia Pharma Group Plc
7.6.1 Company Overview
7.7 GlaxoSmithKline PLC (TESARO, Inc.)
7.7.1 Company Overview
7.7.2 Financial Analysis
7.7.3 Segmental and Regional Analysis
7.7.4 Research & Development Expense
7.8 Helsinn Healthcare SA.
7.8.1 Company Overview
7.9 Heron Therapeutics, Inc.
7.9.1 Company Overview
7.9.2 Financial Analysis
7.9.3 Research & Development Expenses

Companies Mentioned

  • Thermo Fisher Scientific, Inc.
  • General Electric (GE) Co.
  • AstraZeneca PLC
  • Catalent, Inc.
  • Laboratory Corporation of America Holdings
  • Acacia Pharma Group Plc
  • GlaxoSmithKline PLC
  • Helsinn Healthcare SA.
  • Heron Therapeutics, Inc.

Methodology

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