Receptor Endocytosis and Signalling in Health and Disease, Volume 194 in the Progress in Molecular Biology and Translational Science, highlights new advances in the field. Chapters in this release include An overview on receptor endocytosis and signaling, Signaling molecules: Importance in health and disease conditions, Emerging tools for studying of receptor endocytosis and signaling, Endocytosis of EGFR: Signalling in cancer, Endocytosis of AT1 and AT2 receptors: Signalling in the kidney, Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants, Endocytosis of Insulin receptor: Signalling in the regulation of glucose homeostasis, Endocytosis of VEGFR: Role in the regulation of angiogenesis, and more.
Other sections in this new release include Lymphocyte and monocyte/macrophage receptors mediating immune recognition of tumors, Lymphocyte and monocyte/macrophage receptors triggering immune suppression of tumor immunity, Prion receptors and prion internalization and intra- and inter-cellular transport, Multifunctional role of the ubiquitin proteasome pathway in phagocytosis, Adrenoceptors and SCD1 in adipocytes/adipose tissues: the expression and variation in health and obesity, Frizzled receptors and SFRP5 in lipid metabolism: current findings and potential applications.
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Table of Contents
PrefaceIndra Mani and Vijai Singh
1. An overview of receptor endocytosis and signaling
Indra Mani and Vijai Singh
2. Emerging tools for studying receptor endocytosis and signaling
Pratiksha Pandita, Rhea Bhalla, Ashok Saini and Indra Mani
3. Mas receptor endocytosis and signaling in health and disease
Natalia L. Rukavina Mikusic and Mariela M. Gironacci
4. Regulation of transferrin receptor trafficking by optineurin and its disease-associated mutants
Shivranjani C Moharir, Kapil Sirohi and Ghanshyam Swarup
5. The insulin receptor endocytosis
Jiayi Wu, Stella Hayoung Park and Eunhee Choi
6. VEGFR endocytosis: Implications for angiogenesis
Queen Saikia, Hannah Reeve, Areej Alzahrani, William R. Critchley, Elton Zeqiraj, Aysha Divan, Michael A. Harrison and Sreenivasan Ponnambalam
7. Endocytosis and signaling of angiotensin II type 1 receptor
Indra Mani
8. B cell receptor (BCR) endocytosis
Aleah D. Roberts and Justin W. Taraska
9. Multifunctional role of the ubiquitin proteasome pathway in phagocytosis
Angela Lalnunthangi, Gyaltsen Dakpa and Swati Tiwari
10. Receptors of immune cells mediates recognition for tumors
Vandana Anang, Aayushi Singh, Sarat Kumar Kottarath and Chaitenya Verma
11. Role of lymphocytes, macrophages and their receptors in mediating suppression of tumor immunity
Aayushi Singh, Vandana Anang, Komal Kumari, Sarat Kumar Kottarath and Chaitenya Verma
12. Adrenoceptors and SCD1 in adipocytes/adipose tissues: The expression and variation in health and obesity
Dinh-Toi Chu, Nhat-Le Bui and Ngoc Hoan Le
13. Low density lipoprotein receptor endocytosis in cardiovascular disease and factors affecting LDL levels
Rupesh Maurya, Gargi Bhattacherjee, Nisarg Gohil, Khushal Khambhati, Shreya Shakhreliya, Aaradhya Bhatnagar, Priyanka Singh, Suresh Ramakrishna and Vijai Singh
14. Endocytosis of LXRs: Signaling in liver
Mettle Brahma, Soumika Ghosal, Mulaka Maruthi and Suresh K. Kalangi
15. Frizzled receptors and SFRP5 in lipid metabolism: Current findings and potential applications
Dinh-Toi Chu and Thanh-Lam Nguyen