In vitro is the process of performing experiments in a test tube, culture dish, or outside a living organism. In vitro toxicity testing (IVTT) examines the effects of toxic chemical substances on cultured bacteria. It is used to identify hazardous chemical substances and helps detect the toxicity at early stages of the development of new products, such as drugs, cosmetics, and food additives. It is majorly used for safety evaluation in drug development and for ranking the chemicals according to their potency. Moreover, absorption, distribution, metabolism, and excretion (ADME), dose response, and threshold response of drugs are determined by this method.
The growth of the global in vitro toxicity testing market is driven by increase in acceptance by regulatory authorities for using this method for testing. Moreover, ban on animal testing and increase in awareness towards environmental concerns boost the market growth. However, factors such as reduction in adoption rate of in vitro toxicity testing kits and incapability of in vitro models to determine autoimmunity & immunostimulation restrain the market growth. Conversely, rise in focus towards new approaches of 3D cell culture and advancement in genetics & genetic screening approaches are expected to provide potential opportunities for market expansion.
The in vitro toxicity testing market is segmented into type, technology, end users, and region. On the basis of type, the market is categorized into absorption, toxic substances, and dose. Currently, the absorption segment dominates the global in vitro toxicity testing market.
On the basis of end user, the market is categorized into pharmaceuticals, cosmetics & household products, chemicals industry, and food industry. The cosmetics and households products segment is dominant among end users, followed by the pharmaceutical industry. On the basis of technology, the in vitro toxicity testing market is segmented in to cell culture technologies, high throughput technologies, and toxicogenomics. The cell culture technologies segment generated the highest revenue in 2020.
On the basis of region, the in vitro toxicity testing market is analyzed across North America, Europe, Asia-Pacific, and LAMEA. North America is the highest revenue growth, followed by Europe. LAMEA is predicted to grow faster than Asia-Pacific with a CAGR of 16.7% during the forecast period. The LAMEA segment is expected to dominate the in vitro toxicity testing market.
The key players operating in the market include, Acacia Pharma Group Plc., AstraZeneca Plc, GlaxoSmithKline Plc, Helsinn Holdings S.A., Heron Therapeutics Inc., Inc., General Electric Company, EISAI Pharmaceutical Pvt Ltd., Catalent, Inc., Laboratory Corporation of America Holdings., and Thermo Fisher Scientific, Inc.
Major players, such as GlaxoSmithKline Plc (GSK), General Electric Company, AstraZeneca Plc, and others are adopting the acquisition strategy to improve their product portfolio to maintain competition in the market. For instance, AstraZeneca completed the acquisition of Alexion pharmaceuticals, Inc. in July 2021. This acquisition aims to enhance scientific presence in immunology and through Alexion's innovative complement-biology platform and robust pipeline, and is expected to continue to pioneer the discovery and development of medicines for patients with rare diseases. Such instances are expected to provide lucrative opportunities for the major players for the growth of the market.
Key Benefits For Stakeholders
- This report provides a quantitative analysis of the in vitro toxicology industry segments, current trends, estimations, and dynamics of the in vitro toxicity testing market analysis from 2020 to 2030 to identify the prevailing in vitro toxicity testing market opportunities.
- The market research is offered along with information related to key drivers, restraints, and opportunities.
- Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
- In-depth analysis of the in vitro toxicity testing market segmentation, and in vitro toxicity testing market forecast assists to determine the prevailing market opportunities.
- Major countries in each region are mapped according to their revenue contribution to the global in vitro toxicity testing industry.
- Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
- The report includes the analysis of the regional as well as global in vitro toxicity testing market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Type
- Absorption
- Toxic Substances
- Dose
By Technology
- Cell Culture Technologies
- High Throughput Technologies
- Toxicogenomics
By End User
- Cosmetics and Households Products
- Pharmaceuticals Industry
- Food Industry
- Chemicals Industry
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- Italy
- France
- Spain
- Rest of Europe
- Asia-Pacific
- China
- Japan
- India
- South Korea
- Rest Of Asia Pacific
- LAMEA
- Latin America
- Middle East
- Africa
Key Market Players
- General Electric Company
- Thermo Fisher Scientific, Inc.
- Laboratory Corporation of America Holdings
- ACACIA PHARMA GROUP PLC
- TESARO INC.
- Helsinn Holding S.A.
- Heron Therapeutics Inc
- AstraZeneca plc
- Catalent Inc
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Table of Contents
Executive Summary
The in vitro toxicity testing market size was valued at $18.6 billion in 2020, and is estimated to reach $58.9 billion by 2030, growing at a CAGR of 12% from 2021 to 2030.In vitro toxicity testing market size is expected to witness notable growth in the coming years due to the advantages offered by IVTT, such as enhanced accuracy, efficiency, and reliability as compared to other traditional methods. Furthermore, increase in applications of IVTT in food and chemical industries, are the in vitro toxicity testing market trends. Moreover, stringent government regulations aimed at reducing the cruelty while performing experiment on animals, increase illicit drug abuse, and enhanced efficiency of IVTT in diagnosis are the major driving factors for the growth of the market. The impact of these drivers is expected to increase significantly due to increase in awareness about the benefits of IVTT. Some of the restraints associated with the IVTT market are decrease adoption rate of IVTT and incapability of IVTT to detect toxicities due to autoimmunity & immunostimulation. With the advancement in the technology, the challenges of IVTT are expected to reduce in the coming years. A rise in need for testing in various industries such as pharmaceuticals, food, and others, which drives the growth of the in vitro toxicology testing market.
The in vitro toxicology testing market is segmented into type, technology, end users, and region. By type, the market is categorized into absorption, toxic substances, and dose. Currently, the absorption segment dominates the global in vitro toxicity testing market growth.
On the basis of end users, the market is categorized into pharmaceuticals, cosmetics & household products, chemicals industry, and food industry. The cosmetics and households products segment is dominant among end users, followed by the pharmaceutical industry.
On the basis of technology, the in vitro toxicity testing market is segmented into cell culture technologies, high throughput technologies, and toxicogenomics. The cell culture technologies have the highest in vitro toxicity testing market share in 2020.
On the basis of region, the in vitro toxicity testing market is analyzed across North America, Europe, Asia-Pacific, and LAMEA. North America is the highest revenue growth, followed by Europe. LAMEA is predicted to grow faster than Asia-Pacific with a CAGR of 16.7% during the forecast period. The LAMEA segment is expected to dominate the in vitro toxicity testing market.
The key players operating in this market include, Acacia Pharma Group Plc., AstraZeneca Plc, GlaxoSmithKline Plc, Helsinn Holdings S.A., Heron Therapeutics Inc., Inc., General Electric Company, EISAI Pharmaceutical Pvt Ltd., Catalent, Inc., Laboratory Corporation of America Holdings., and Thermo Fisher Scientific, Inc.
Major players are adopting product launch and acquisition as key developmental strategies to improve the product portfolio of warehouse robots. For instance, in April 2019, Thermo Fisher acquired Brammer Bio for approximately $1.67 billion in cash. Brammer Bio is a leading viral vector contract development and manufacturing for company for gene and cell therapies.
Several manufacturers in the global in vitro toxicity testing market stopped their business activities in 2020 due to lockdowns implemented in developed and developing countries, owing to ban on industrial activities due to the COVID-19 pandemic. This halt in production activities impacted the revenue of the in vitro toxicity testing manufacturing companies. For instance, net sales of General Electric Company dropped by 2.2% from January 2021 to December 2021. In addition, lack of man power and raw materials affected the supply chain of the global in vitro toxicity testing market. However, the market is projected to cover from the 1st quarter of 2023, due to reduced restrictions and reopening of the global in vitro toxicity testing industry. Moreover, in 2021, with the availability of vaccine against COVID-19, the in vitro toxicology industry re-opened at full pace with a start of 2022.
KEY FINDINGS OF STUDY
- The report provides an extensive analysis of the current and emerging global in vitro toxicity testing market trends and dynamics.
- By type, the absorption segment dominated the market in terms of revenue in 2020.
- On the basis of technology, the cell culture technologies segment generated the highest revenue in 2020.
- By end-user, the cosmetics and households products segment dominated the market in terms of revenue in 2020.
- The report provides an extensive analysis of the trends and emerging opportunities of the market.
- In depth, the global in vitro toxicity testing market analysis is conducted by constructing estimations for the key segments between 2020 and 2030.
Companies Mentioned
- General Electric Company
- Thermo Fisher Scientific, Inc.
- Laboratory Corporation of America Holdings
- ACACIA PHARMA GROUP PLC
- TESARO INC.
- Helsinn Holding S.A.
- Heron Therapeutics Inc
- AstraZeneca plc
- Catalent Inc
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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Table Information
Report Attribute | Details |
---|---|
No. of Pages | 231 |
Published | March 2022 |
Forecast Period | 2020 - 2030 |
Estimated Market Value ( USD | $ 18565.2 million |
Forecasted Market Value ( USD | $ 59147.6 million |
Compound Annual Growth Rate | 12.3% |
Regions Covered | Global |
No. of Companies Mentioned | 9 |