The key factors that drive the growth of the market are increase in demand for biopharmaceuticals as downstream processing plays a key role in providing pure biopharmaceutical products. In addition, rise in R&D expenditure for biopharmaceutical products majorly drive the growth of the market. Furthermore, rise in adoption of single-use systems, low risk of product cross contamination and cost-effectiveness are the key factors anticipating the growth of market in upcoming years. In addition, single-use system in downstream processing is highly efficient and cost-effective, which attract pharmaceutical manufacturers to adopt disposable bioprocessing products drive the growth of the market in upcoming years. However, dearth and shortage of skilled bioprocess engineers is expected to restrain the market growth in upcoming years. Moreover, untapped markets such as China and India, offer profitable opportunities to expand this market.
The downstream processing market is segmented on the basis of technique, product, system application, end user, and region. By technique, it is categorized into purification, separation, and clarification/concentration. Depending on product, it is classified into chromatography columns and resins, filters, membrane absorbers, and other products. By system, it is bifurcated into single use system and re-usable system. By application, it is divided into monoclonal antibody production, vaccine production, insulin production, immunoglobulin production, erythropoietin production, and other applications. By end user, it is categorized into biopharmaceutical manufacturers, and contract manufacturing organizations (CMOs).
Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).
North America accounted for the largest market share in the downstream processing market in 2020 and is expected to retain its dominance throughout the forecast period. This is primarily attributed to increase in R&D activities for biopharmaceuticals, considerable investments made by the market players and increase in government support are fueling the growth of the market in this region.
The major companies profiled in this report include, 3M Company, Sartorius Stedim Biotech S.A, Danaher Corporation, Thermo Fisher Scientific Inc., Merck & Co., Inc., Boehringer Ingelheim, Lonza Group AG, Eppendorf AG, Finesse Solutions, Inc. and Repligen Corporation
Key Benefits For Stakeholders
- This report provides a quantitative analysis of the market segments, current trends, estimations, and dynamics of theDownstream Processing Market Size analysis from 2020 to 2030 to identify the prevailing downstream processing market opportunities.
- The market research is offered along with information related to key drivers, restraints, and opportunities.
- Porter's five forces analysis highlights the potency of buyers and suppliers to enable stakeholders make profit-oriented business decisions and strengthen their supplier-buyer network.
- In-depth analysis of the downstream processing market segmentation assists to determine the prevailing market opportunities.
- Major countries in each region are mapped according to their revenue contribution to the global market.
- Market player positioning facilitates benchmarking and provides a clear understanding of the present position of the market players.
- The report includes the analysis of the regional as well as global downstream processing market trends, key players, market segments, application areas, and market growth strategies.
Key Market Segments
By Technology
- Purification
- Separation
- Clarification/Concentration
By Product
- Chromatography Columns and Resins
- Filters
- Membrane Adsorbers
- Other Products
By System
- Single Use System
- Re Usable System
By Application
- Monoclonal Antibody Production
- Vaccine Production
- Insulin Production
- Immunoglobulin Production
- Erythropoietin Production
- Other Applications
By End User
- Biopharmaceutical Manufacturers
- Contract Manufacturing Organizations (CMOs)
By Region
- North America
- U.S.
- Canada
- Mexico
- Europe
- Germany
- France
- U.K.
- Italy
- Spain
- Rest of Europe
- Asia-Pacific
- Japan
- China
- India
- Australia
- South Korea
- Rest Of Asia Pacific
- LAMEA
- Brazil
- Saudi Arabia
- South Africa
- Rest of LAMEA
Key Market Players
- Thermo Fisher Scientific Inc.
- Sartorius Stedim Biotech S.A
- Bio Rad Laboratories, Inc
- 3M Company
- Lonza Group AG
- Eppendorf AG
- Marathon Petroleum Corporation
- Merck KGaA.
- Religen Inc
- Agilent Technologies Inc.
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Table of Contents
Executive Summary
According to this report titled, 'Downstream Processing Market,' the Downstream Processing Market Size at $21.8 billion in 2020, and is estimated to reach $92.0 billion by 2030, growing at a CAGR of 13.5% from 2021 to 2030.Downstream processing involves the process of purification and recovery of biosynthetic products, which includes mainly pharmaceuticals and are obtained from the natural sources. Downstream processing consists of five stages that include solid-liquid separation, intracellular products are released, and concentration and chromatography method is used for purification and formulation. The separation method includes methods such as flocculation, centrifugation flotation, and filtration.
Rise in demand for single-use systems, lower risk of cross-contamination and reduced manufacturing costs and increase in demand for biopharmaceuticals drive the Downstream Processing Market Growth. In addition, the increase in the prevalence of chronic disease such as cancer, genetic disorders, and rare disease among others and COVID-19 pandemic has increased the demand for vaccines and antibody production, which is expected to drive the growth of the market in upcoming years. However, dearth and shortage of skilled bioprocess engineers restrain the market growth. Moreover, emerging markets such as China and India, offer profitable opportunities to expand this market.
The Downstream Processing Market Analysis on the basis of technique, product, system, application, end user, and region. By technique, it is categorized into purification, separation, and clarification/concentration. Depending on product, it is classified into chromatography columns and resins, filters, membrane adsorbers, and other products.
By system, it is bifurcated into single use system and re-usable system. By application, it is divided into monoclonal antibody production, vaccine production, insulin production, immunoglobulin production, erythropoietin production, and other applications. By end user, it is categorized into biopharmaceutical manufacturers, and contract manufacturing organizations (CMOs). Region wise, the market is analyzed across North America (the U.S., Canada, and Mexico), Europe (Germany, France, the UK, Italy, Spain, and rest of Europe), Asia-Pacific (Japan, China, Australia, India, South Korea, and rest of Asia-Pacific), and LAMEA (Brazil, South Africa, Saudi Arabia, and rest of LAMEA).
By technique, the purification segment generated the highest revenue in the downstream processing market in 2020 owing to rise in demand for monoclonal antibodies due to rise in the cases of cancer and increase in adoption of biopharmaceuticals across the world. By product, the chromatography columns and resins segment generated the highest revenue in the downstream processing market in 2020, owing to increasing demand for therapeutic antibodies, public-private investment in pharmaceutical & life science research as well as constant need for newer and different types of columns and resins.
By system, the single use system segment generated the highest revenue in the downstream processing market in 2020, owing to reduction in bioprocessing time, increase in downstream processing annual output and reduced operational costs while using single-use segments. By application, the monoclonal antibody production segment generated the highest revenue in the downstream processing market in 2020, owing to prevalence of cancer, rise in regulatory approvals and launch of therapies for cancer treatment. By end user, the biopharmaceutical manufacturers segment generated the highest revenue in the downstream processing market in 2020, owing to increasing demand for biopharmaceuticals among the aging population.
By region, North America accounted for largest Downstream Processing Market Share in 2020 and is expected to retain its dominance throughout the forecast period. This is primarily attributed to increase in R&D activities for biopharmaceuticals, considerable investments made by the market players and increase in government support.
Asia-Pacific witnessed the highest growth rate for the downstream processing market and is expected to continue this trend throughout the forecast period, which is attributed to rise in expenditure on healthcare and improvement in the medical and healthcare infrastructure. In addition, the key market players focus on opportunities offered by the growing demand for single-use systems in the downstream process. This system is highly cost-effective, which has gained popularity among end users. Moreover, significant growth of the pharmaceutical and biotechnology industries supplements the market growth.
Key findings of the Study
- On the basis of technique, the purification segment held 43.98% share in the global Downstream Processing Industry in 2020.
- On the basis of product, the chromatography columns and resins segment held the largest Downstream Processing Market Size in 2020, and is expected to remain dominant throughout the forecast period.
- According to the application, the monoclonal antibody production segment exhibits the largest Downstream Processing Industryshare in 2020, and is expected to remain dominant throughout the forecast period.
- On the basis of end-user, the biopharmaceutical manufacturers segment held the largest market share in 2020, and is expected to remain dominant throughout the forecast period.
- Region-wise, North America is expected to experience the highest market share during the forecast period. This was attributed to an increase in R&D activities for biopharmaceuticals, considerable investments made by the market players and increase in government support.
Companies Mentioned
- Thermo Fisher Scientific Inc.
- Sartorius Stedim Biotech S.A
- Bio Rad Laboratories, Inc
- 3M Company
- Lonza Group AG
- Eppendorf AG
- Marathon Petroleum Corporation
- Merck KGaA.
- Religen Inc
- Agilent Technologies Inc.
Methodology
The analyst offers exhaustive research and analysis based on a wide variety of factual inputs, which largely include interviews with industry participants, reliable statistics, and regional intelligence. The in-house industry experts play an instrumental role in designing analytic tools and models, tailored to the requirements of a particular industry segment. The primary research efforts include reaching out participants through mail, tele-conversations, referrals, professional networks, and face-to-face interactions.
They are also in professional corporate relations with various companies that allow them greater flexibility for reaching out to industry participants and commentators for interviews and discussions.
They also refer to a broad array of industry sources for their secondary research, which typically include; however, not limited to:
- Company SEC filings, annual reports, company websites, broker & financial reports, and investor presentations for competitive scenario and shape of the industry
- Scientific and technical writings for product information and related preemptions
- Regional government and statistical databases for macro analysis
- Authentic news articles and other related releases for market evaluation
- Internal and external proprietary databases, key market indicators, and relevant press releases for market estimates and forecast
Furthermore, the accuracy of the data will be analyzed and validated by conducting additional primaries with various industry experts and KOLs. They also provide robust post-sales support to clients.
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