An Epidemiological Update on COVID-19 brings recent findings about the pandemic to the forefront. The reference is a compilation of eleven chapters contributed by expert scholars in epidemiology and medicine that cover topics of interest to anyone interested in COVID-19 monitoring and response measures. The topics also indicate some clinical areas of interest to COVID-19 researchers that have received attention due to the pandemic. It covers basic knowledge about respiratory conditions associated with SARS-CoV-2 infection and COVID-19 epidemiology.
These topics are complemented with chapters detailing the symptoms and biochemical mechanisms of novel coronavirus infections intended for readers with an advanced level of understanding of life sciences and medicine. Special topics such as the immune response to Sars-CoV-2, and, recombinant drugs for COVID-19, are also covered in this book. Each chapter is organized in a reader-friendly format and includes a list of references.
Table of Contents
Chapter 1 Acute Respiratory Distress Syndrome (Ards)- Introduction
- Pathophysiology
- Causes Of Ards
- Epidemiology
- Risk Factors
- Symptoms Of Ards
- Diagnosis Of Ards
- Treatment Of Ards
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Shabeer Ahmed N And Ashar Waheed. M. P. Introduction To Coronavirus
- The Emergence Of The Coronavirus
- Structure Of The Coronavirus
- Respiratory Virus Infection In Humans And Its Detection
- Genomic Variations In Sars-Cov-2
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Mohamed Tariq N.P.M., D. Manikandan And S.U. Mohammed Riyaz Introduction
- The Spread Of The Virus
- Overview
- Worst
- Best Memories
- Worst Memories
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- G. Kalaiarasi, E. Saravanakumar, B. Keerthana And B. Prabha Introduction
- Animal Models Of Neurotropic Coronavirus Infections
- Mechanism Of Cns Invasion
- Potential Routes And Mechanisms Of Cns Involvement In Covid-19 33 Principle Mechanisms Of Sars-Cov-2 Cns Infection
- Neuropathology Of Sars-Cov-2
- Hypoxic Brain Injury
- Immune-Mediated Injury
- Neurological Manifestations And Complications Of Covid-19
- Cns Manifestation Associated With Covid-19
- Pns Manifestations Associated With Covid-19
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- R. Nishanthi, S. Malathi, E.G. Jagan, D. Manikandan And S.U.Mohammed Riyaz Role Of Intermediate Host- Place Of Re-Assortment
- Coronavirus
- Natural Reservoirs Of Virus - Bats
- Major Virus Outbreak-Bat As Predominant Intermediate Host
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- K. Priadharsini, D. Manikandan, Sajeer Koolath, G. Rajasekhar Reddy And S.U. Mohammed Riyaz Introduction
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Kailasam Saravana Mani Introduction
- Endocytic Pathway For Sars-Cov2 Entry
- Coronavirus Structural Proteins
- Hydroxychloroquine As Sars-Cov2 Inhibitors
- Clinical Trials With Hydroxychloroquine (Hcq) For Covid-19
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- B. Prabha, G. Kalaiarasi And B. Keerthana Introduction
- Root Of Covid-19
- Immunogenicity
- Corona Viral Genome Structure
- Sars-Cov-2 Virus
- Conventional Coronavirus Vaccines
- Inactivated Vaccine
- Live-Attenuated Vaccine
- Viral Vector Vaccine
- Subunit Vaccine
- Nucleic Acid Vaccine
- The Obstructions In The Development Of Sars-2 Vaccine
- The Current Pipeline For Sars-Cov-2 Vaccines
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Pandurangan Ranjani, Atulbabu Govindaraju, D. Manikandan And S.U.Mohammed Riyaz Introduction
- Vaccine Development Stages
- Pre-Clinical Stage
- Clinical Trial Phase I
- Vaccine Design
- Vaccine Platforms
- Vaccine Candidates For Covid-19
- Vaccine Development In India
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- K. Priadharsini, D. Manikandan, P. Rajesh Babu And S.U. Mohammed Riyaz Spread Of Coronaviruses
- Asymptomatic And Human To Human Transmission Of Sars-Cov-2
- Strengths And Limitations
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Sri Ranjani Sakthinathan, D. Manikandan, Sajeer Koolath, G. Rajasekhar Reddy And Karthic Kumar Balan Introduction
- Mechanism Of Immune System In The Body
- Impact Of Covid-19 On The Human Body
- Effect On Coagulation
- Pulmonary Effects
- Cardiac Effects
- Renal Effects
- Effect On Brain
- Effect On Git
- Psychological Effects
- Pathogenesis Of Covid-19
- Asymptomatic Phase
- Infection Of The Upper Respiratory Tract
- Progression Of The Infection To Lower Respiratory Tract
- Viral Transmission
- Clinical Features
- Clinical Spectrum
- Immune Response Against Covid-19
- Conclusion
- Consent For Publication
- Conflict Of Interest
- Acknowledgements
- References
- Subject Index
Author
- Manikandan Dhayalan
- S.U.Mohammed Riyaz
- S. Parveen