The Eye, Volume Four, the latest release in the Stem Cell Innovation in Health and Disease series, addresses the recent data accumulated on the potential applications of stem cells to treat eye diseases. This volume highlights the recent development of cutting-edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to cure eye diseases.
The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors in the field. This is a timely and fascinating collection of information and new discoveries that provides a contemporary snapshot album on the fast-moving field of regenerative medicine and stem cell therapeutics.
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Table of Contents
Cutting edge Research on the Eye stem cell functions 1. Organoid-based modality of Eye function and cellular processes 2. Organoid culture system in Eye Development and Pathogenesis and genetic screening
Cutting edge Research on stem cell application in the lung diseases (from bench to bed) 3. Stem Cell-Based Organoid Culture 4. Contributions of Stem Cell Engineering to New Therapies of Eye Diseases 5. Preclinical and Clinical Applications of Innovative Gene Editing Technologies iPSCs as an Inexhaustible Source of Disease 6. The Gold Standard Embryonic Stem Cells in Eye Regeneration and Diseases 7. Preclinical and Clinical Applications Mesenchymal Stem/Stromal Cells in Eye Diseases 8. Update on Stem/Progenitor Cell-based Clinical Trials of Eye Disorders
Authors
Eman E. Taher Professor, Department of Microbiology and Clinical Parasitology, Research Institute of Ophthalmology, Cairo, Egypt. Dr. Eman E. Taher is a Professor in the Department of Microbiology and Clinical Parasitology at the Research Institute of Ophthalmology. The institute studies and performs different diagnostic techniques for parasites especially those affecting the eyes.Dr. Taher is the head of the Clinical Parasitology Unit. His extensive work has been on the diagnosis of Acanthamoeba, Toxoplasma, Toxocara and Schistosomiasis, as well as other different parasites, which has yielded over 20 papers, with different faculties, post-doctoral fellows and students. Additionally, Dr. Taher has also completed extensive research on different molecular diagnostic techniques for different parasites including electrophoresis, PCR, Western blot, DNA-extraction, ELISA and dot-ELISA. In addition, to stem cell preparation, characterization being a member of the stem cell laboratory at the Research Institute of Ophthalmology, he earned a six-month scholarship at the Eye and Ear Institute, Pittsburgh University, USA. His research portfolio includes variable papers on different parasites. Mohamed Elalfy Ophthalmologist - Private Practice, UK. Dr. Mohamed Elalfy is a fellow of the Royal College of Ophthalmologists in London, the Royal College of Surgeons in Edinburgh, the Royal College of Physicians and Surgeons in Glasgow, the European Board of Ophthalmology and the International Council of Ophthalmology. He is an active member of the European Society of Cataract and Refractive Surgery, and of The European Cornea Society and Refractive Surgery. Mr Elalfy travels abroad as an invited guest to share his expertise through teaching and live surgeries. He is Fellowship Programme Director in Corneoplastic Unit, Queen Victoria Hospital where he trains four fellows annually. Having obtained two academic qualifications through his career of more than 15 years in ophthalmology and with more than 30 peer-reviewed publications, Mr Elalfy puts evidence-based ophthalmology in the heart of his practice.
